Parathyroid cancer medical therapy: Difference between revisions

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Latest revision as of 20:54, 8 January 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

The predominant therapy for parathyroid cancer is surgical resection. Adjunctive supportive therapy, chemotherapy, and radiation may be required. Supportive therapy for parathyroid cancer includes IV fluids, diuretics, and calcimimetic agents.

Medical Therapy

There are different types of treatment for patients with parathyroid cancer.
Treatment includes the control of hypercalcemia among patients who have an overactive parathyroid gland.

Standard Therapy

Four types of standard treatment are used:

Surgery
Radiation therapy
Chemotherapy
Supportive care
Follow-up tests may be needed

Supportive Care

Supportive care is given to lessen the problems caused by the disease or its treatment. Supportive care for hypercalcemia caused by parathyroid cancer may include the following:

Intravenous (IV) fluids
Diuretics
Antiresorptive agents such as biphosphonates, gallium, or mithramycin

Calcimimetic agents that directly block secretion of the parathyroid hormone from the glands

Gallium nitrate to reduce the calcium levels
Calcitonin to control the calcium levels^[1]

References

↑ Parathyroid cancer. Cancer.gov (2015). http://www.cancer.gov/types/parathyroid/hp Accessed on December 29, 2015

Template:WikiDoc Sources

[1] Parathyroid cancer. Cancer.gov (2015). http://www.cancer.gov/types/parathyroid/hp Accessed on December 29, 2015

[1]

@@ Line 3: / Line 3: @@
 {{CMG}}; {{AE}} {{Ammu}}
 ==Overview==
+The predominant therapy for parathyroid cancer is [[surgery|surgical resection]]. Adjunctive supportive therapy, [[chemotherapy]], and [[radiation]] may be required. Supportive therapy for parathyroid cancer includes [[IV fluids]], [[diuretics]], and calcimimetic agents.
 ==Medical Therapy==
-There are different types of treatment for patients with parathyroid cancer.
+* There are different types of treatment for patients with parathyroid cancer.
-Treatment includes control of hypercalcemia (too much calcium in the blood) in patients who have an overactive parathyroid gland.
+* Treatment includes the control of [[hypercalcemia]] among patients who have an overactive parathyroid gland.
-* Conventional treatment with intravenous fluids, diuretics, and antiresorptive agents such as biphosphonates, gallium, or mithramycin may help control the hypercalcemia.  Calcimimetic agents that directly block secretion of the parathyroid hormone from the glands may offer an important new approach to medical therapy of primary HPT associated with parathyroid cancer.
+===Standard Therapy===
-Four types of standard treatment are used:
+* Four types of standard treatment are used:
-Surgery
+:* [[Surgery]]
-Radiation therapy
+:* [[Radiation therapy]]
-Chemotherapy
+:* [[Chemotherapy]]
-Supportive care
+:* [[Supportive care]]
-Follow-up tests may be needed.
+:* Follow-up tests may be needed
-* Gallium nitrate is used to reduce the calcium levels.
+====Supportive Care====
-* Calcitonin is used to control the calcium levels
+* Supportive care is given to lessen the problems caused by the disease or its treatment. Supportive care for hypercalcemia caused by parathyroid cancer may include the following:
-Radiation therapy
+:* Intravenous (IV) fluids
+:* [[Diuretics]]
-Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells or stop them from growing. There are two types of radiation therapy. External radiation therapy uses a machine outside the body to send radiation toward the cancer. Internal rad iation therapy uses a radioactive substance sealed in needles, seeds, wires, or catheters that are placed directly into or near the cancer. The way the radiation therapy is given depends on the type and stage of the cancer being treated.
+:* Antiresorptive agents such as [[biphosphonates]], [[gallium]], or [[mithramycin]]
+* Calcimimetic agents that directly block secretion of the parathyroid hormone from the glands
-Chemotherapy
+:* [[Gallium nitrate]] to reduce the calcium levels
+:* [[Calcitonin]] to control the calcium levels<ref> Parathyroid cancer. Cancer.gov (2015). http://www.cancer.gov/types/parathyroid/hp  Accessed on December 29, 2015</ref>
-Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). The way the chemotherapy is given depends on the type and stage of the cancer being treated.
-Supportive care
-Supportive care is given to lessen the problems caused by the disease or its treatment. Supportive care for hypercalcemia caused by parathyroid cancer may include the following:
-Intravenous (IV) fluids.
-Drugs that increase how much urine the body makes.
-Drugs that stop the body from absorbing calcium from the food we eat.
-Drugs that stop the parathyroid gland from making parathyroid hormone.
 ==References==
 {{Reflist|2}}
+[[Category:Endocrine system]]
-[[Category:Templates]]
+[[Category:Endocrinology]]
+[[Category:Otolaryngology]]
+[[Category:Disease]]
+[[Category:Genetic disorders]]
+[[Category:Types of cancer]]
+[[Category:Hereditary cancers]]
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