Hamartoma CT: Difference between revisions
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{{Hamartoma}} | {{Hamartoma}} | ||
{{CMG}}{{AE}}{{MV}} | {{CMG}}{{AE}}{{MV}} {{VKG}} | ||
==Overview== | ==Overview== | ||
CT scan is the imaging modality of choice for the diagnosis of hamartoma. On CT scan, hamartoma is characterized by focal collections of fat, a lesion with a smooth edge, and collections of fat alternating with foci of calcification. | [[CT-scans|CT]] scan is the imaging modality of choice for the diagnosis of [[hamartoma]]. On [[Computed tomography|CT scan]], [[hamartoma]] is characterized by focal collections of [[fat]], a lesion with a smooth edge, and collections of fat alternating with foci of [[calcification]]. | ||
==CT== | ==CT scan== | ||
=== Pulmonary Hamartoma === | |||
Chest [[Computed tomography|CT]] scan may be helpful in the diagnosis of [[pulmonary]] [[hamartoma]]. Findings on [[Computed tomography|CT]] scan suggestive of hamartoma include:<ref name="pmid12376601">{{cite journal |vauthors=Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ |title=Fat-containing lesions of the chest |journal=Radiographics |volume=22 Spec No |issue= |pages=S61–78 |year=2002 |pmid=12376601 |doi=10.1148/radiographics.22.suppl_1.g02oc08s61 |url=}}</ref><ref name="hbook">Brant WE, Helms CA.(2007) Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins.ISBN:0781765188</ref><ref name="SiegelmanKhouri1986">{{cite journal|last1=Siegelman|first1=S S|last2=Khouri|first2=N F|last3=Scott|first3=W W|last4=Leo|first4=F P|last5=Hamper|first5=U M|last6=Fishman|first6=E K|last7=Zerhouni|first7=E A|title=Pulmonary hamartoma: CT findings.|journal=Radiology|volume=160|issue=2|year=1986|pages=313–317|issn=0033-8419|doi=10.1148/radiology.160.2.3726106}}</ref><ref name="GaerteMeyer2002">{{cite journal|last1=Gaerte|first1=Scott C.|last2=Meyer|first2=Cristopher A.|last3=Winer-Muram|first3=Helen T.|last4=Tarver|first4=Robert D.|last5=Conces|first5=Dewey J.|title=Fat-containing Lesions of the Chest|journal=RadioGraphics|volume=22|issue=suppl_1|year=2002|pages=S61–S78|issn=0271-5333|doi=10.1148/radiographics.22.suppl_1.g02oc08s61}}</ref><ref name="pmid24119266">{{cite journal |vauthors=Gleeson T, Thiessen R, Hannigan A, Murphy D, English JC, Mayo JR |title=Pulmonary hamartomas: CT pixel analysis for fat attenuation using radiologic-pathologic correlation |journal=J Med Imaging Radiat Oncol |volume=57 |issue=5 |pages=534–43 |date=October 2013 |pmid=24119266 |doi=10.1111/1754-9485.12083 |url=}}</ref><ref name="pmid28775580">{{cite journal |vauthors=Singh H, Khanna SK, Chandran V, Jetley RK |title=PULMONARY HAMARTOMA |journal=Med J Armed Forces India |volume=55 |issue=1 |pages=79–80 |date=January 1999 |pmid=28775580 |pmc=5531795 |doi=10.1016/S0377-1237(17)30328-3 |url=}}</ref> | |||
:* Isodense or hypodense solid [[Mass|masses]] | |||
:* [[Heterogeneous]] contrast enhancement relative to adjacent normal [[parenchyma]] | |||
:*Presence of [[fat]] in a well circumscribed [[solitary pulmonary nodule]] which does not demonstrate significant growth | |||
:*The fat components may be localized or generalized within the nodule and will typically have a Hounsfield measurement of -40 to -120 HU | |||
:*[[Calcification]] is typically dispersed in the form of multiple [[Lump|lumps]] throughout the lesion in a [[popcorn]] configuration | |||
=== Spleen Hamartoma === | |||
[[Abdominal]] [[Computed tomography|CT]] scan may be helpful in the diagnosis of [[Spleen|splenic]] [[hamartoma]]. Findings on [[abdominal]] [[Computed tomography|CT]] scan suggestive of [[Spleen|splenic]] [[hamartoma]] include:<ref name="pmid25238476">{{cite journal |vauthors=Soto-Medina CA, Mier-Escurra EA, Treviño-Garza F, Ripa-Galván P |title=[Splenic hamartoma. Case report] |language=Spanish; Castilian |journal=Cirugía Y Cirujanos |volume=82 |issue=3 |pages=328–31 |year=2014 |pmid=25238476 |doi= |url=}}</ref> | |||
* Isodense or hypodense solid masses | |||
* | * [[Heterogeneous]] contrast enhancement relative to adjacent normal [[parenchyma]] | ||
=== Renal Hamartoma === | |||
:*Lesions involve the cortex and demonstrate macroscopic fat (less than -20 HU) | [[Abdominal]] CT scan may be helpful in the diagnosis of [[renal]] hamartoma. Findings on abdominal CT scan suggestive of renal hamartoma include:<ref name="pmid25238476" /><ref name="pmid9503504">{{cite journal |vauthors=Eble JN |title=Angiomyolipoma of kidney |journal=Seminars in Diagnostic Pathology |volume=15 |issue=1 |pages=21–40 |year=1998 |pmid=9503504 |doi= |url=}}</ref> | ||
:*Small renal hamartomas volume averaging may make differentiation from a small cyst difficult | :*[[Lesion|Lesions]] involve the [[cortex]] and demonstrate macroscopic fat (less than -20 HU) | ||
:*Renal hamartomas are | :*Small renal [[hamartomas]] volume averaging may make differentiation from a small [[cyst]] difficult | ||
:*Calcification is rare | :*[[Renal]] hamartomas are [[fat]]-poor | ||
:*[[Calcification]] is rare | |||
=== Hypothalamic Hamartoma === | |||
:* Iso-attenuating nodule of soft tissue | Head CT scan may be helpful in the diagnosis of [[hypothalamic]] [[hamartoma]]. Findings on head CT scan suggestive of [[hypothalamic]] [[hamartoma]] include:<ref name="pmid252384762">{{cite journal |vauthors=Soto-Medina CA, Mier-Escurra EA, Treviño-Garza F, Ripa-Galván P |title=[Splenic hamartoma. Case report] |language=Spanish; Castilian |journal=Cirugía Y Cirujanos |volume=82 |issue=3 |pages=328–31 |year=2014 |pmid=25238476 |doi= |url=}}</ref><ref name="pmid27936889">{{cite journal |vauthors=Leiter Herrán F, Restrepo CS, Alvarez Gómez DI, Suby-Long T, Ocazionez D, Vargas D |title=Hamartomas from head to toe: an imaging overview |journal=Br J Radiol |volume=90 |issue=1071 |pages=20160607 |date=March 2017 |pmid=27936889 |pmc=5601532 |doi=10.1259/bjr.20160607 |url=}}</ref><ref name="pmid2501981">{{cite journal |vauthors=Burton EM, Ball WS, Crone K, Dolan LM |title=Hamartoma of the tuber cinereum: a comparison of MR and CT findings in four cases |journal=AJNR Am J Neuroradiol |volume=10 |issue=3 |pages=497–501 |date=1989 |pmid=2501981 |doi= |url=}}</ref> | ||
:* Iso-attenuating [[nodule]] of soft-[[tissue]] | |||
:* Calcification is rare | :* Calcification is rare | ||
:* There is no contrast enhancement | :* There is no contrast [[enhancement]] | ||
==References== | ==References== | ||
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American Roentgen Ray Society Images of Hamartoma CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Vamsikrishna Gunnam M.B.B.S [3]
Overview
CT scan is the imaging modality of choice for the diagnosis of hamartoma. On CT scan, hamartoma is characterized by focal collections of fat, a lesion with a smooth edge, and collections of fat alternating with foci of calcification.
CT scan
Pulmonary Hamartoma
Chest CT scan may be helpful in the diagnosis of pulmonary hamartoma. Findings on CT scan suggestive of hamartoma include:[1][2][3][4][5][6]
- Isodense or hypodense solid masses
- Heterogeneous contrast enhancement relative to adjacent normal parenchyma
- Presence of fat in a well circumscribed solitary pulmonary nodule which does not demonstrate significant growth
- The fat components may be localized or generalized within the nodule and will typically have a Hounsfield measurement of -40 to -120 HU
- Calcification is typically dispersed in the form of multiple lumps throughout the lesion in a popcorn configuration
Spleen Hamartoma
Abdominal CT scan may be helpful in the diagnosis of splenic hamartoma. Findings on abdominal CT scan suggestive of splenic hamartoma include:[7]
- Isodense or hypodense solid masses
- Heterogeneous contrast enhancement relative to adjacent normal parenchyma
Renal Hamartoma
Abdominal CT scan may be helpful in the diagnosis of renal hamartoma. Findings on abdominal CT scan suggestive of renal hamartoma include:[7][8]
- Lesions involve the cortex and demonstrate macroscopic fat (less than -20 HU)
- Small renal hamartomas volume averaging may make differentiation from a small cyst difficult
- Renal hamartomas are fat-poor
- Calcification is rare
Hypothalamic Hamartoma
Head CT scan may be helpful in the diagnosis of hypothalamic hamartoma. Findings on head CT scan suggestive of hypothalamic hamartoma include:[9][10][11]
- Iso-attenuating nodule of soft-tissue
- Calcification is rare
- There is no contrast enhancement
References
- ↑ Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ (2002). "Fat-containing lesions of the chest". Radiographics. 22 Spec No: S61–78. doi:10.1148/radiographics.22.suppl_1.g02oc08s61. PMID 12376601.
- ↑ Brant WE, Helms CA.(2007) Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins.ISBN:0781765188
- ↑ Siegelman, S S; Khouri, N F; Scott, W W; Leo, F P; Hamper, U M; Fishman, E K; Zerhouni, E A (1986). "Pulmonary hamartoma: CT findings". Radiology. 160 (2): 313–317. doi:10.1148/radiology.160.2.3726106. ISSN 0033-8419.
- ↑ Gaerte, Scott C.; Meyer, Cristopher A.; Winer-Muram, Helen T.; Tarver, Robert D.; Conces, Dewey J. (2002). "Fat-containing Lesions of the Chest". RadioGraphics. 22 (suppl_1): S61–S78. doi:10.1148/radiographics.22.suppl_1.g02oc08s61. ISSN 0271-5333.
- ↑ Gleeson T, Thiessen R, Hannigan A, Murphy D, English JC, Mayo JR (October 2013). "Pulmonary hamartomas: CT pixel analysis for fat attenuation using radiologic-pathologic correlation". J Med Imaging Radiat Oncol. 57 (5): 534–43. doi:10.1111/1754-9485.12083. PMID 24119266.
- ↑ Singh H, Khanna SK, Chandran V, Jetley RK (January 1999). "PULMONARY HAMARTOMA". Med J Armed Forces India. 55 (1): 79–80. doi:10.1016/S0377-1237(17)30328-3. PMC 5531795. PMID 28775580.
- ↑ 7.0 7.1 Soto-Medina CA, Mier-Escurra EA, Treviño-Garza F, Ripa-Galván P (2014). "[Splenic hamartoma. Case report]". Cirugía Y Cirujanos (in Spanish; Castilian). 82 (3): 328–31. PMID 25238476.
- ↑ Eble JN (1998). "Angiomyolipoma of kidney". Seminars in Diagnostic Pathology. 15 (1): 21–40. PMID 9503504.
- ↑ Soto-Medina CA, Mier-Escurra EA, Treviño-Garza F, Ripa-Galván P (2014). "[Splenic hamartoma. Case report]". Cirugía Y Cirujanos (in Spanish; Castilian). 82 (3): 328–31. PMID 25238476.
- ↑ Leiter Herrán F, Restrepo CS, Alvarez Gómez DI, Suby-Long T, Ocazionez D, Vargas D (March 2017). "Hamartomas from head to toe: an imaging overview". Br J Radiol. 90 (1071): 20160607. doi:10.1259/bjr.20160607. PMC 5601532. PMID 27936889.
- ↑ Burton EM, Ball WS, Crone K, Dolan LM (1989). "Hamartoma of the tuber cinereum: a comparison of MR and CT findings in four cases". AJNR Am J Neuroradiol. 10 (3): 497–501. PMID 2501981.