Behçet's disease risk factors: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Behçet's disease}} | {{Behçet's disease}} | ||
{{CMG}} | {{CMG}}; {{AE}} {{HQ}} | ||
==Overview== | ==Overview== | ||
Common risk factors in the development of Behcet disease may be occupational, environmental, [[Genetics|genetic]], and [[Virus|viral]]. Behçet's disease can affect people in any [[Ageing|age]], but the most common age is 20~30 years old. Behçet's disease is more common in Middle East and Japan then in other [[race]]. It is rare in America. Researches demonstrate that the presence of the [[gene]] [[Human leukocyte antigen|HLA]]–B51 is a risk factor for Behçet's disease. | |||
==Risk Factors== | ==Risk Factors== | ||
The underlying cause of Behçet’s disease is not clear. | The underlying cause of Behçet’s disease is not clear. It is suggested that the following factors may be associated with the disease: | ||
*Genetic predisposition: Researches demonstrate that the presence of the gene | *[[Genetics|Genetic]] predisposition: Researches demonstrate that the presence of the gene [[Human leukocyte antigen|HLA]]–B51 is a risk factor for Behçet's disease.<ref name="pmid10449951">{{cite journal| author=Treudler R, Orfanos CE, Zouboulis CC| title=Twenty-eight cases of juvenile-onset Adamantiades-Behçet disease in Germany. | journal=Dermatology | year= 1999 | volume= 199 | issue= 1 | pages= 15-9 | pmid=10449951 | doi=10.1159/000018197 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10449951 }} </ref><ref name="pmid11147770">{{cite journal| author=Soy M, Erken E, Konca K, Ozbek S| title=Smoking and Behçet's disease. | journal=Clin Rheumatol | year= 2000 | volume= 19 | issue= 6 | pages= 508-9 | pmid=11147770 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11147770 }} </ref> | ||
*Age: Behçet's disease can affect people in any age, but the most common age is 20~30 years old. | *[[Ageing|Age]]: Behçet's disease can affect people in any [[Ageing|age]], but the most common age is 20~30 years old. | ||
*Gender: Behçet's disease most commonly affects men than women. | *Gender: Behçet's disease most commonly affects men than women. | ||
*Race: Behçet's disease is more common in Middle East and Japan then in other race. It is rare in America. | *[[Race]]: Behçet's disease is more common in Middle East and Japan then in other [[race]]. It is rare in America.<ref name="pmid17334337">{{cite journal| author=Yazici H, Fresko I, Yurdakul S| title=Behçet's syndrome: disease manifestations, management, and advances in treatment. | journal=Nat Clin Pract Rheumatol | year= 2007 | volume= 3 | issue= 3 | pages= 148-55 | pmid=17334337 | doi=10.1038/ncprheum0436 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17334337 }} </ref> | ||
==References== | ==References== | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
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[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Rheumatology]] | [[Category:Rheumatology]] | ||
Latest revision as of 20:36, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
Common risk factors in the development of Behcet disease may be occupational, environmental, genetic, and viral. Behçet's disease can affect people in any age, but the most common age is 20~30 years old. Behçet's disease is more common in Middle East and Japan then in other race. It is rare in America. Researches demonstrate that the presence of the gene HLA–B51 is a risk factor for Behçet's disease.
Risk Factors
The underlying cause of Behçet’s disease is not clear. It is suggested that the following factors may be associated with the disease:
- Genetic predisposition: Researches demonstrate that the presence of the gene HLA–B51 is a risk factor for Behçet's disease.[1][2]
- Age: Behçet's disease can affect people in any age, but the most common age is 20~30 years old.
- Gender: Behçet's disease most commonly affects men than women.
- Race: Behçet's disease is more common in Middle East and Japan then in other race. It is rare in America.[3]
References
- ↑ Treudler R, Orfanos CE, Zouboulis CC (1999). "Twenty-eight cases of juvenile-onset Adamantiades-Behçet disease in Germany". Dermatology. 199 (1): 15–9. doi:10.1159/000018197. PMID 10449951.
- ↑ Soy M, Erken E, Konca K, Ozbek S (2000). "Smoking and Behçet's disease". Clin Rheumatol. 19 (6): 508–9. PMID 11147770.
- ↑ Yazici H, Fresko I, Yurdakul S (2007). "Behçet's syndrome: disease manifestations, management, and advances in treatment". Nat Clin Pract Rheumatol. 3 (3): 148–55. doi:10.1038/ncprheum0436. PMID 17334337.