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==Overview==
==Overview==
Most women with GDM will return to their pre-pregnancy glycemic status after delivery, but there is an increased chance of developing overt diabetes or prediabetes during the next 5 years. Recurrent GDM is another subject that physicians should be aware of.


==Natural History==
==Natural History==
 
*If GDM is left untreated, serious fetal complications can develop during pregnancy, and progression to overt diabetes  can also occur in the long term.
==Complications==
Unlike pre-gestational diabetes, gestational diabetes generally does not cause birth defects. Birth defects usually originate sometime during the first [[trimester]] (before the 13th week) of pregnancy. Additionally, poor control of diabetes can lead to a variety of birth defects involving the heart, kidneys, eyes, and central nervous system, as well as increased risk of [[miscarriage]].
 
Infants of mothers with gestational diabetes are vulnerable to several chemical imbalances, such as low serum calcium and low serum magnesium levels, but in general, there are two major problems of gestational diabetes: macrosomia and hypoglycemia.<ref name=UMM>{{cite web | Content was last reviewed by a University of Maryland Medicine expert | title =Gestational Diabetes | publisher=University of Maryland Medicine | work =An overview of gestational diabetes, including risk factors and treatment | url=http://www.umm.edu/diabetes-info/gesta.htm | year = 2003 | month= May 14 | accessdate=2006-11-29}}</ref>
 
'''For Mother'''
* [[Hypertension]]
* [[Preeclampsia]]
* Increased risk for developing type 2 diabetes. High blood sugar (glucose) levels often go back to normal after delivery. However, women with gestational diabetes should be watched closely after giving birth and at regular doctor's appointments to screen for signs of diabetes. '''Many women with gestational diabetes develop diabetes within 5 - 10 years after delivery'''. The risk may be increased in [[Obesity|obese women]].
 
'''For Baby'''
* [[Macrosomia]] (macrosomia can also increase the likelihood of a caesarean-section delivery)
* [[Hypoglycemia]]
* [[Jaundice]]
* Low [[calcium]] and [[magnesium]]
* [[Respiratory distress syndrome]] (RDS)
* Increased risk for childhood and adult obesity
* Increased risk of type 2 diabetes later in life
 
==Prognosis==
==Prognosis==
Gestational diabetes generally resolves once the baby is born. However, women diagnosed with gestational diabetes have an increased risk of developing [[diabetes mellitus]] in the future. Women requiring insulin to manage gestational diabetes have a 50% risk of developing diabetes within the next five years. <ref name=AMN>{{cite web | Carla Janzen, MD, Jeffrey S. Greenspoon, MD | title =Gestational Diabetes | publisher=Armenian Medical Network | work =Diabetes Mellitus & Pregnancy - Gestational Diabetes | url=http://www.health.am/pregnancymore/diabetes-intrapartum-postpartum-management/ | year = 2006 | accessdate=2007-02-28}}</ref>
*Most of women with GDM return to their pre pregnancy glycemic status after delivery.
*Women diagnosed with gestational diabetes have an increased risk of developing overt [[diabetes mellitus]] in the future. Women requiring insulin to manage gestational diabetes have a 50% risk of developing diabetes within the next five years.<ref name=AMN>{{cite web | Carla Janzen, MD, Jeffrey S. Greenspoon, MD | title =Gestational Diabetes | publisher=Armenian Medical Network | work =Diabetes Mellitus & Pregnancy - Gestational Diabetes | url=http://www.health.am/pregnancymore/diabetes-intrapartum-postpartum-management/ | year = 2006 | accessdate=2007-02-28}}</ref>
*One-third to two-thirds of women will re-experience GDM in subsequent pregnancies.<ref name="pmid20630491">{{cite journal |vauthors=Getahun D, Fassett MJ, Jacobsen SJ |title=Gestational diabetes: risk of recurrence in subsequent pregnancies |journal=Am. J. Obstet. Gynecol. |volume=203 |issue=5 |pages=467.e1–6 |year=2010 |pmid=20630491 |doi=10.1016/j.ajog.2010.05.032 |url=}}</ref><ref name="pmid11315827">{{cite journal |vauthors=MacNeill S, Dodds L, Hamilton DC, Armson BA, VandenHof M |title=Rates and risk factors for recurrence of gestational diabetes |journal=Diabetes Care |volume=24 |issue=4 |pages=659–62 |year=2001 |pmid=11315827 |doi= |url=}}</ref>
*Risk factors for the recurrence of GDM include older age, multiparity, higher maternal weight in the index pregnancy, and weight gain between pregnancies.<ref name="pmid8941462">{{cite journal |vauthors=Moses RG |title=The recurrence rate of gestational diabetes in subsequent pregnancies |journal=Diabetes Care |volume=19 |issue=12 |pages=1348–50 |year=1996 |pmid=8941462 |doi= |url=}}</ref><ref name="pmid11315827">{{cite journal |vauthors=MacNeill S, Dodds L, Hamilton DC, Armson BA, VandenHof M |title=Rates and risk factors for recurrence of gestational diabetes |journal=Diabetes Care |volume=24 |issue=4 |pages=659–62 |year=2001 |pmid=11315827 |doi= |url=}}</ref>


==References==
==References==
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[[Category:Obstetrics]]
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[[Category:Endocrinology]]
[[Category:Endocrinology]]
[[Category:Emergency medicine]]
[[Category:Emergency medicine]]
[[Category:Primary care]]
[[Category:Needs content]]
[[Category:Needs overview]]

Latest revision as of 21:51, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]


Overview

Most women with GDM will return to their pre-pregnancy glycemic status after delivery, but there is an increased chance of developing overt diabetes or prediabetes during the next 5 years. Recurrent GDM is another subject that physicians should be aware of.

Natural History

  • If GDM is left untreated, serious fetal complications can develop during pregnancy, and progression to overt diabetes can also occur in the long term.

Prognosis

  • Most of women with GDM return to their pre pregnancy glycemic status after delivery.
  • Women diagnosed with gestational diabetes have an increased risk of developing overt diabetes mellitus in the future. Women requiring insulin to manage gestational diabetes have a 50% risk of developing diabetes within the next five years.[1]
  • One-third to two-thirds of women will re-experience GDM in subsequent pregnancies.[2][3]
  • Risk factors for the recurrence of GDM include older age, multiparity, higher maternal weight in the index pregnancy, and weight gain between pregnancies.[4][3]

References

  1. "Gestational Diabetes". Diabetes Mellitus & Pregnancy - Gestational Diabetes. Armenian Medical Network. 2006. Retrieved 2007-02-28. Text " Carla Janzen, MD, Jeffrey S. Greenspoon, MD " ignored (help)
  2. Getahun D, Fassett MJ, Jacobsen SJ (2010). "Gestational diabetes: risk of recurrence in subsequent pregnancies". Am. J. Obstet. Gynecol. 203 (5): 467.e1–6. doi:10.1016/j.ajog.2010.05.032. PMID 20630491.
  3. 3.0 3.1 MacNeill S, Dodds L, Hamilton DC, Armson BA, VandenHof M (2001). "Rates and risk factors for recurrence of gestational diabetes". Diabetes Care. 24 (4): 659–62. PMID 11315827.
  4. Moses RG (1996). "The recurrence rate of gestational diabetes in subsequent pregnancies". Diabetes Care. 19 (12): 1348–50. PMID 8941462.

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