Cryoglobulinemia causes: Difference between revisions

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__NOTOC__
__NOTOC__
{{Cryoglobulinemia}}
{{Cryoglobulinemia}}
{{CMG}} {{AE}} {{LRO}}
{{CMG}} {{AE}} {{FT}}


==Overview==
==Overview==
Common causes of cryoglobulinemia are primarily hematologic, oncologic, and rheumatic. Less commonly, cryoglobulinemia can be caused by infections such as [[HIV]] or [[Hepatitis C]]..
Common causes of cryoglobulinemia are primarily hematologic, oncologic, and rheumatic. Less commonly, cryoglobulinemia can be caused by infections such as [[HIV]] or [[Hepatitis C]].


==Causes==
==Causes==
===Common Causes===
===Common Causes===
The common causes of cryoglobulinemia are as follows:<ref name="pmid16026843">{{cite journal| author=Scotto G, Cibelli DC, Saracino A, Prato R, Palumbo E, Fazio V et al.| title=Cryoglobulinemia in subjects with HCV infection alone, HIV infection and HCV/HIV coinfection. | journal=J Infect | year= 2006 | volume= 52 | issue= 4 | pages= 294-9 | pmid=16026843 | doi=10.1016/j.jinf.2005.05.025 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16026843  }} </ref><ref name="pmid29558353">{{cite journal| author=Suszek D, Majdan M| title=[Cryoglobulins and cryoglobulinemic vasculitis]. | journal=Wiad Lek | year= 2018 | volume= 71 | issue= 1 pt 1 | pages= 59-63 | pmid=29558353 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29558353  }} </ref><ref name="pmid27034078">{{cite journal| author=Blank N, Lorenz HM| title=[Cryoglobulinemic vasculitis]. | journal=Z Rheumatol | year= 2016 | volume= 75 | issue= 3 | pages= 303-15 | pmid=27034078 | doi=10.1007/s00393-016-0076-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27034078  }} </ref><ref name="pmid10787003">{{cite journal| author=Ramos-Casals M, Trejo O, García-Carrasco M, Cervera R, Font J| title=Mixed cryoglobulinemia: new concepts. | journal=Lupus | year= 2000 | volume= 9 | issue= 2 | pages= 83-91 | pmid=10787003 | doi=10.1191/096120300678828127 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10787003  }} </ref>
*[[B-cell hyperactivation ]]
*[[B-cell hyperactivation ]]
*[[B-cell hyperproliferation]]
*[[B-cell hyperproliferation]]
Line 17: Line 18:
*[[Rheumatoid disease]]
*[[Rheumatoid disease]]
*[[Systemic lupus erythematosus]]
*[[Systemic lupus erythematosus]]
*[[Waldenström macroglobulinaemia]]
*[[Waldenström macroglobulinaemia|Waldenstrom macroglobulinaemia]]


===Causes by Organ System===
===Causes by Organ System===
{|style="width:80%; height:100px" border="1"
{| style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Hypersensitivity vasculitis]],  [[Raynaud's phenomenon]]
| style="width:75%" bgcolor="Beige" ; border="1" | [[Hypersensitivity vasculitis]],  [[Raynaud's phenomenon]]
|-
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dental'''
| '''Dental'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| [[Purpura]]
| bgcolor="Beige" | [[Purpura]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
| '''Ear Nose Throat'''
|bgcolor="Beige"| [[Sjögren's syndrome]]
| bgcolor="Beige" | [[Sjögren's syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Environmental'''
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| [[Sjögren's syndrome]]
| bgcolor="Beige" | [[Sjögren's syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| [[B-cell hyperactivation ]],  [[B-cell hyperproliferation]],  [[Leukemia]],  [[Multiple myeloma]],  [[Myeloma]],  [[Primary macroglobulinemia]],  [[Purpura]],  [[Raynaud's phenomenon]]
| bgcolor="Beige" | [[B-cell hyperactivation ]] ,  [[B-cell hyperproliferation]],  [[Leukemia]],  [[Multiple myeloma]],  [[Myeloma]],  [[Primary macroglobulinemia]],  [[Purpura]],  [[Raynaud's phenomenon]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| [[Hepatitis c]],  [[Hiv]],  [[Mycoplasma pneumonia]]
| bgcolor="Beige" | [[Hepatitis c]],  [[Hiv]],  [[Mycoplasma pneumonia]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| [[Leukemia]],  [[Multiple myeloma]],  [[Myeloma]],  [[Primary macroglobulinemia]],  [[Waldenström macroglobulinaemia]]
| bgcolor="Beige" | [[Leukemia]],  [[Multiple myeloma]],  [[Myeloma]],  [[Primary macroglobulinemia]],  [[Waldenström macroglobulinaemia]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
| '''Ophthalmologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
| '''Overdose/Toxicity'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Psychiatric'''
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Pulmonary'''
| '''Pulmonary'''
|bgcolor="Beige"| [[Mycoplasma pneumonia]]
| bgcolor="Beige" | [[Mycoplasma pneumonia]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| '''Renal/Electrolyte'''
|bgcolor="Beige"| [[Glomerulonephritis]]
| bgcolor="Beige" | [[Glomerulonephritis]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| [[Arthropathy]],  [[Rheumatoid arthritis]],  [[Rheumatoid disease]],  [[Systemic lupus erythematosus]]
| bgcolor="Beige" | [[Arthropathy]],  [[Rheumatoid arthritis]],  [[Rheumatoid disease]],  [[Systemic lupus erythematosus]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Sexual'''
| '''Sexual'''
|bgcolor="Beige"| [[Hiv]]
| bgcolor="Beige" | [[Hiv]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Trauma'''
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Urologic'''
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|}
|}


===Causes in Alphabetical Order===
===Causes in Alphabetical Order===
{{columns-list|3|
{{columns-list|
*[[Arthropathy]]
*[[Arthropathy]]
*[[B-cell hyperactivation ]]
*[[B-cell hyperactivation ]]

Latest revision as of 20:41, 10 January 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Feham Tariq, MD [2]

Overview

Common causes of cryoglobulinemia are primarily hematologic, oncologic, and rheumatic. Less commonly, cryoglobulinemia can be caused by infections such as HIV or Hepatitis C.

Causes

Common Causes

The common causes of cryoglobulinemia are as follows:[1][2][3][4]

Causes by Organ System

Cardiovascular Hypersensitivity vasculitis, Raynaud's phenomenon
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic Purpura
Drug Side Effect No underlying causes
Ear Nose Throat Sjögren's syndrome
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic Sjögren's syndrome
Hematologic B-cell hyperactivation  , B-cell hyperproliferation, Leukemia, Multiple myeloma, Myeloma, Primary macroglobulinemia, Purpura, Raynaud's phenomenon
Iatrogenic No underlying causes
Infectious Disease Hepatitis c, Hiv, Mycoplasma pneumonia
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Leukemia, Multiple myeloma, Myeloma, Primary macroglobulinemia, Waldenström macroglobulinaemia
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Mycoplasma pneumonia
Renal/Electrolyte Glomerulonephritis
Rheumatology/Immunology/Allergy Arthropathy, Rheumatoid arthritis, Rheumatoid disease, Systemic lupus erythematosus
Sexual Hiv
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

References

  1. ↑ Scotto G, Cibelli DC, Saracino A, Prato R, Palumbo E, Fazio V; et al. (2006). "Cryoglobulinemia in subjects with HCV infection alone, HIV infection and HCV/HIV coinfection". J Infect. 52 (4): 294–9. doi:10.1016/j.jinf.2005.05.025. PMID 16026843.
  2. ↑ Suszek D, Majdan M (2018). "[Cryoglobulins and cryoglobulinemic vasculitis]". Wiad Lek. 71 (1 pt 1): 59–63. PMID 29558353.
  3. ↑ Blank N, Lorenz HM (2016). "[Cryoglobulinemic vasculitis]". Z Rheumatol. 75 (3): 303–15. doi:10.1007/s00393-016-0076-4. PMID 27034078.
  4. ↑ Ramos-Casals M, Trejo O, García-Carrasco M, Cervera R, Font J (2000). "Mixed cryoglobulinemia: new concepts". Lupus. 9 (2): 83–91. doi:10.1191/096120300678828127. PMID 10787003.


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