Congenital rubella syndrome differential diagnosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{ | [[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Congenital_rubella_syndrome]] | ||
{{ | {{CMG}}; {{AE}} {{DN}} | ||
==Overview== | ==Overview== | ||
The most important congenital infections, which can be transmitted vertically from mother to fetus are the [[TORCH infections]]. These infections have overlapping features and hence, must be differentiated from CRS.<ref name="pmid25677998">{{cite journal |vauthors=Neu N, Duchon J, Zachariah P |title=TORCH infections |journal=Clin Perinatol |volume=42 |issue=1 |pages=77–103, viii |year=2015 |pmid=25677998 |doi=10.1016/j.clp.2014.11.001 |url=}}</ref><ref name="pmid25654000">{{cite journal |vauthors=Ajij M, Nangia S, Dubey BS |title=Congenital rubella syndrome with blueberry muffin lesions and extensive metaphysitis |journal=J Clin Diagn Res |volume=8 |issue=12 |pages=PD03–4 |year=2014 |pmid=25654000 |pmc=4316306 |doi=10.7860/JCDR/2014/10271.5293 |url=}}</ref> | |||
==Differentiating Congenital Rubella Syndrome from other Diseases== | ==Differentiating Congenital Rubella Syndrome from other Diseases== | ||
The most important congenital infections, which can be transmitted vertically from mother to fetus are the TORCH infections. These infections have overlapping features and hence, must be differentiated from CRS: | The most important congenital infections, which can be transmitted vertically from mother to fetus are the [[TORCH infections]]. These infections have overlapping features and hence, must be differentiated from CRS:<ref name="pmid25677998">{{cite journal |vauthors=Neu N, Duchon J, Zachariah P |title=TORCH infections |journal=Clin Perinatol |volume=42 |issue=1 |pages=77–103, viii |year=2015 |pmid=25677998 |doi=10.1016/j.clp.2014.11.001 |url=}}</ref><ref name="pmid25654000">{{cite journal |vauthors=Ajij M, Nangia S, Dubey BS |title=Congenital rubella syndrome with blueberry muffin lesions and extensive metaphysitis |journal=J Clin Diagn Res |volume=8 |issue=12 |pages=PD03–4 |year=2014 |pmid=25654000 |pmc=4316306 |doi=10.7860/JCDR/2014/10271.5293 |url=}}</ref> | ||
<SMALL> | |||
{| class="wikitable" | {| class="wikitable" | ||
!Congenital Infection | !Congenital Infection | ||
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|- | |- | ||
!Toxoplasmosis | !Toxoplasmosis | ||
| | |— | ||
| | | | ||
* [[Petechiae]] | * [[Petechiae]] | ||
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|✔ | |✔ | ||
|Diffuse intracranial calcifications | |Diffuse intracranial calcifications | ||
| | |— | ||
|- | |- | ||
!Treponema pallidum | !Treponema pallidum | ||
| | |— | ||
| | | | ||
* [[Petechiae]] | * [[Petechiae]] | ||
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* [[Glaucoma]] | * [[Glaucoma]] | ||
|✔ | |✔ | ||
| | |— | ||
| | |— | ||
| | |— | ||
| | |— | ||
|- | |- | ||
!Rubella | !Rubella | ||
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* [[Patent ductus arteriosus (PDA)]] | * [[Patent ductus arteriosus (PDA)]] | ||
* [[Pulmonary artery stenosis]] | * [[Pulmonary artery stenosis]] | ||
* [[Coarctation of the aorta]] | |||
* [[Myocarditis]] | * [[Myocarditis]] | ||
| | | | ||
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* [[Chorioretinitis]] | * [[Chorioretinitis]] | ||
* [[Cataracts]] | * [[Cataracts]] | ||
* [[Glaucoma]] | |||
* [[Microphthalmia]] | * [[Microphthalmia]] | ||
|✔ | |✔ | ||
|✔ | |✔ | ||
| | |✔ | ||
| | |— | ||
|✔ | |✔ | ||
|- | |- | ||
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* [[Chorioretinitis]] | * [[Chorioretinitis]] | ||
|✔ | |✔ | ||
| | |— | ||
|✔ | |✔ | ||
|Periventricular calcifications | |Periventricular calcifications | ||
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|✔ | |✔ | ||
|✔ | |✔ | ||
| | |— | ||
|✔ | |✔ | ||
|- | |- | ||
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* [[Cataracts]] | * [[Cataracts]] | ||
|✔ | |✔ | ||
| | |— | ||
| | |— | ||
| | |— | ||
| | |— | ||
|} | |} | ||
</SMALL> | |||
==References== | ==References== | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Emergency medicine]] | |||
[[Category:Disease]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Infectious disease]] | |||
[[Category:Pediatrics]] | |||
[[Category:Obstetrics]] |
Latest revision as of 21:03, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
The most important congenital infections, which can be transmitted vertically from mother to fetus are the TORCH infections. These infections have overlapping features and hence, must be differentiated from CRS.[1][2]
Differentiating Congenital Rubella Syndrome from other Diseases
The most important congenital infections, which can be transmitted vertically from mother to fetus are the TORCH infections. These infections have overlapping features and hence, must be differentiated from CRS:[1][2]
Congenital Infection | Cardiac Findings | Skin Findings | Ocular Findings | Hepatosplenomegaly | Hydrocephaly | Microcephaly | Intracranial Calcifications | Hearing deficits |
---|---|---|---|---|---|---|---|---|
Toxoplasmosis | — | ✔ | ✔ | ✔ | Diffuse intracranial calcifications | — | ||
Treponema pallidum | — | ✔ | — | — | — | — | ||
Rubella | ✔ | ✔ | ✔ | — | ✔ | |||
Cytomegalovirus (CMV) | ✔ | ✔ | — | ✔ | Periventricular calcifications | ✔ | ||
Herpes simplex virus (HSV) | ✔ | ✔ | ✔ | — | ✔ | |||
Parvovirus B19 | ✔ | — | — | — | — |
References
- ↑ 1.0 1.1 Neu N, Duchon J, Zachariah P (2015). "TORCH infections". Clin Perinatol. 42 (1): 77–103, viii. doi:10.1016/j.clp.2014.11.001. PMID 25677998.
- ↑ 2.0 2.1 Ajij M, Nangia S, Dubey BS (2014). "Congenital rubella syndrome with blueberry muffin lesions and extensive metaphysitis". J Clin Diagn Res. 8 (12): PD03–4. doi:10.7860/JCDR/2014/10271.5293. PMC 4316306. PMID 25654000.