Toxic shock syndrome surgery: Difference between revisions

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==Overview:==
==Overview:==
Surgery is not the first-line treatment option for patients with toxic shock syndrome(TSS). Surgical debridement is usually reserved for patients with either necrotizing fasciitis(NF), and patients with deep-seeded pyogenic infection.
[[Surgery]] is not the first-line treatment option for patients with [[toxic shock syndrome]](TSS). Surgical [[debridement]] is usually reserved for patients with either [[necrotizing fasciitis]](NF), and patients with deep-seeded [[pyogenic]] infection. [[Urgent care|Urgent]] surgical [[debridement]] was recommended for all patients who develop [[Necrotizing fasciitis|NF]] earlier, but is under questioning nowadays.
 
Urgent surgical debridement was recommended for all patients who develop NF earlier, but is under questioning nowadays.
 
ne of the symptoms of streptococcal toxic shock syndrome is extreme infection of the skin and deeper parts is called [[fasciitis necroticans|necrotizing fasciitis]]. This often requires prompt surgical treatment.
* Although every medical reference continously announce that early surgical debridement in STSS patients can lead to better management of the disease, there are no enough studies to suggest this idea.
* 9560122
 
*
 
*
The recommendation of immediate radical excision of necrotic tissue in patients with STSS NF is not supported by clinical studies and should be reconsidered.M. Kotb. Bacterial pyrogenic exotoxins as superantigens. Clin Microbiol Rev, 8 (1995), pp. 411–426
 
Early and immediate surgical debridement should be considered in most patients with suspected streptococcal toxic shock syndrome (i.e., those who present with fever, pain, soft-tissue swelling, and/or vesicle and bullae formation).
 
Aggressive surgical debridement of infected tissue including fascia is imperative and mandatory if a site of potential infection is identified. Repeated and sequential operative and bedside debridements of infected tissue are often needed, particularly if necrotizing fasciitis is present in streptococcal disease. [null <nowiki>[19]</nowiki>]
<ref name="pmid1989">{{cite journal |vauthors=Polna I, Aleksandrowicz J |title=Effect of adsorbents on IgM and IgG measles antibodies |journal=Acta Virol. |volume=19 |issue=6 |pages=449–56 |year=1975 |pmid=1989 |doi= |url=}}</ref>
In addition to surgical debridements, fasciotomy or amputation may be needed to halt the progression of the disease.Stevens DL, Tanner MH, Winship J, et al. Severe group A streptococcal infections associated with a shock-like syndrome. N Engl J Med. 1989;321:1-7
<ref name="urlChapter 125. Infections of the Skin, Muscles, and Soft Tissues | Harrisons Principles of Internal Medicine, 18e | AccessMedicine | McGraw-Hill Medical">{{cite web |url=http://accessmedicine.mhmedical.com/content.aspx?bookid=331&sectionid=40726869 |title=Chapter 125. Infections of the Skin, Muscles, and Soft Tissues &#124; Harrison's Principles of Internal Medicine, 18e &#124; AccessMedicine &#124; McGraw-Hill Medical |format= |work= |accessdate=}}</ref>


==Surgery==
==Surgery==
Prompt, aggressive, immediate exploration and debridement of patients thought to have deep tissue localized infection was believed to be a surgical emergency . Surgical exploration of the susceptible infected tissue may help with the early and definitive diagnosis of NF. In NF related TSS patients, infection usually is more extensive than is apparent from external examination. Although the necessity of surgical debridement, the recommendation of immediate radical excision of necrotic tissue in patients with streptococcal TSS NF is not supported by clinical studies and should be reconsidered as an emergency treatment in TSS management.
Prompt, aggressive, immediate exploration and [[debridement]] of patients thought to have deep tissue localized [[infection]] was believed to be a [[surgical emergency]] <ref name="pmid9560122">{{cite journal |vauthors=Schurr M, Engelhardt S, Helgerson R |title=Limb salvage for streptococcal gangrene of the extremity |journal=Am. J. Surg. |volume=175 |issue=3 |pages=213–7 |year=1998 |pmid=9560122 |doi= |url=}}</ref>. Surgical [[exploration]] of the susceptible infected tissue may help with the early and definitive diagnosis of NF. In NF related [[Toxic shock syndrome|TSS]] patients, infection usually is more extensive than is apparent from external examination. Although the necessity of surgical [[debridement]], the recommendation of immediate radical excision of [[necrotic tissue]] in patients with [[Streptococcus|streptococcal]] TSS NF is not supported by clinical studies and should be reconsidered as an emergency treatment in TSS management<ref name="pmid7553574">{{cite journal |vauthors=Kotb M |title=Bacterial pyrogenic exotoxins as superantigens |journal=Clin. Microbiol. Rev. |volume=8 |issue=3 |pages=411–26 |year=1995 |pmid=7553574 |pmc=174633 |doi= |url=}}</ref>.


==Indications==
==Indications==
Surgical debridement of body tissues should be considered in these patients:
Surgical [[debridement]] of body tissues should be considered in these patients:
* Localized source of infection is diagnosed
* [[Localized disease|Localized]] source of [[infection]] is diagnosed
* Streptococcal NF-related TSS patients
* [[Streptococcus|Streptococcal]] [[Necrotizing fasciitis|NF]]-related [[Toxic shock syndrome|TSS]] patients<ref name="urlChapter 125. Infections of the Skin, Muscles, and Soft Tissues | Harrisons Principles of Internal Medicine, 18e | AccessMedicine | McGraw-Hill Medical">{{cite web |url=http://accessmedicine.mhmedical.com/content.aspx?bookid=331&sectionid=40726869 |title=Chapter 125. Infections of the Skin, Muscles, and Soft Tissues &#124; Harrison's Principles of Internal Medicine, 18e &#124; AccessMedicine &#124; McGraw-Hill Medical |format= |work= |accessdate=}}</ref>


==References==
==References==
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Latest revision as of 00:27, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview:

Surgery is not the first-line treatment option for patients with toxic shock syndrome(TSS). Surgical debridement is usually reserved for patients with either necrotizing fasciitis(NF), and patients with deep-seeded pyogenic infection. Urgent surgical debridement was recommended for all patients who develop NF earlier, but is under questioning nowadays.

Surgery

Prompt, aggressive, immediate exploration and debridement of patients thought to have deep tissue localized infection was believed to be a surgical emergency [1]. Surgical exploration of the susceptible infected tissue may help with the early and definitive diagnosis of NF. In NF related TSS patients, infection usually is more extensive than is apparent from external examination. Although the necessity of surgical debridement, the recommendation of immediate radical excision of necrotic tissue in patients with streptococcal TSS NF is not supported by clinical studies and should be reconsidered as an emergency treatment in TSS management[2].

Indications

Surgical debridement of body tissues should be considered in these patients:

References

  1. Schurr M, Engelhardt S, Helgerson R (1998). "Limb salvage for streptococcal gangrene of the extremity". Am. J. Surg. 175 (3): 213–7. PMID 9560122.
  2. Kotb M (1995). "Bacterial pyrogenic exotoxins as superantigens". Clin. Microbiol. Rev. 8 (3): 411–26. PMC 174633. PMID 7553574.
  3. "Chapter 125. Infections of the Skin, Muscles, and Soft Tissues | Harrison's Principles of Internal Medicine, 18e | AccessMedicine | McGraw-Hill Medical".


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