Q fever natural history, complications, and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
Acute Q fever has a good prognosis even without treatment. [[Chronic]] Q fever has a less favorable prognosis. | |||
==Natural history== | ==Natural history== | ||
===Acute Q fever=== | ===Acute Q fever=== | ||
If left untreated, most patients will recover within several months.<ref name="pmid88923">{{cite journal |vauthors=Ishikawa H, Maeda H, Takamatsu H, Saito Y |title=Systemic hyalinosis (juvenile hyaline fibromatosis). Ultrastructure of the hyaline with particular reference to the cross-banded structure |journal=Arch. Dermatol. Res. |volume=265 |issue=2 |pages=195–206 |year=1979 |pmid=88923 |doi= |url=}}</ref> | |||
===Chronic Q fever=== | ===Chronic Q fever=== | ||
If left untreated, chronic Q fever is usually deadly. However, with appropriate treatment, the case fatality rate is around 10%.<ref name="pmid88923">{{cite journal |vauthors=Ishikawa H, Maeda H, Takamatsu H, Saito Y |title=Systemic hyalinosis (juvenile hyaline fibromatosis). Ultrastructure of the hyaline with particular reference to the cross-banded structure |journal=Arch. Dermatol. Res. |volume=265 |issue=2 |pages=195–206 |year=1979 |pmid=88923 |doi= |url=}}</ref> | |||
==Complications== | ==Complications== | ||
===Pulmonary | ===Pulmonary === | ||
*[[Atypical pneumonia]] | *[[Atypical pneumonia]] | ||
*[[Acute respiratory distress syndrome]] [[Acute respiratory distress syndrome|ARDS]] in rare cases | *[[Acute respiratory distress syndrome]] [[Acute respiratory distress syndrome|(ARDS)]] in rare cases | ||
===Cardiac | ===Cardiac === | ||
*[[Endocarditis]] | *[[Endocarditis]] | ||
*[[Pericarditis]] or [[myocarditis]] | *[[Pericarditis]] or [[myocarditis]] | ||
*[[Pericardial effusion]] | *[[Pericardial effusion]] | ||
===Hepatic | ===Hepatic === | ||
*[[Hepatic fibrosis]] and [[cirrhosis]] | *[[Hepatic fibrosis]] and [[cirrhosis]] | ||
===Musculoskeletal | ===Musculoskeletal === | ||
*[[Osteomyelitis]] | *[[Osteomyelitis]] | ||
*[[Arthritis]] | *[[Arthritis]] | ||
===Obstetric | ===Obstetric === | ||
*[[Abortion]] | *[[Abortion]] | ||
*[[IUGR]] | *[[IUGR]] | ||
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==Prognosis== | ==Prognosis== | ||
===Acute Q fever=== | ===Acute Q fever=== | ||
* Acute Q fever is responsive to treatment and even without treatment, [[mortality rate]] is 1-2% | * Acute Q fever is responsive to treatment and even without treatment, [[mortality rate]] is 1-2%. | ||
===Chronic Q fever=== | ===Chronic Q fever=== | ||
* Chronic Q fever is more serious with | * Chronic Q fever is more serious, with a case fatality rate of 10% after treatment.<ref name="pmid18452690">{{cite journal |vauthors=Hartzell JD, Wood-Morris RN, Martinez LJ, Trotta RF |title=Q fever: epidemiology, diagnosis, and treatment |journal=Mayo Clin. Proc. |volume=83 |issue=5 |pages=574–9 |year=2008 |pmid=18452690 |doi=10.4065/83.5.574 |url=}}</ref> | ||
==References== | ==References== | ||
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[[Category:Needs content]] | [[Category:Needs content]] | ||
[[Category:Bacterial diseases]] | [[Category:Bacterial diseases]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Acute Q fever has a good prognosis even without treatment. Chronic Q fever has a less favorable prognosis.
Natural history
Acute Q fever
If left untreated, most patients will recover within several months.[1]
Chronic Q fever
If left untreated, chronic Q fever is usually deadly. However, with appropriate treatment, the case fatality rate is around 10%.[1]
Complications
Pulmonary
- Atypical pneumonia
- Acute respiratory distress syndrome (ARDS) in rare cases
Cardiac
Hepatic
Musculoskeletal
Obstetric
Prognosis
Acute Q fever
- Acute Q fever is responsive to treatment and even without treatment, mortality rate is 1-2%.
Chronic Q fever
- Chronic Q fever is more serious, with a case fatality rate of 10% after treatment.[2]
References
- ↑ 1.0 1.1 Ishikawa H, Maeda H, Takamatsu H, Saito Y (1979). "Systemic hyalinosis (juvenile hyaline fibromatosis). Ultrastructure of the hyaline with particular reference to the cross-banded structure". Arch. Dermatol. Res. 265 (2): 195–206. PMID 88923.
- ↑ Hartzell JD, Wood-Morris RN, Martinez LJ, Trotta RF (2008). "Q fever: epidemiology, diagnosis, and treatment". Mayo Clin. Proc. 83 (5): 574–9. doi:10.4065/83.5.574. PMID 18452690.