Microsporidiosis natural history, complications and prognosis: Difference between revisions
Ochuko Ajari (talk | contribs) No edit summary |
m (Changes made per Mahshid's request) |
||
| (12 intermediate revisions by 5 users not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Microsporidiosis}} | {{Microsporidiosis}} | ||
{{CMG}} | {{CMG}}; {{AE}}{{AY}} | ||
==Overview== | ==Overview== | ||
If left untreated, [[immunocompetent]] patients resolve the disease completely within 2 weeks while [[immunocompromised]] patients might develop [[chronic diarrhea]]. Common complications of microsporidiosis include [[weight loss]], [[dehydration]], and [[acalculous cholecystitis]]. Prognosis is generally excellent in [[immunocompetent]] patients while [[Immunocompromised|immunocompromised patients]] are more vulnerable to developing [[chronic disease]] and complications. | |||
==Natural History, Complications and | ==Natural History== | ||
If left untreated, microsporidiosis is self-resolving with complete recovery within 14 days in [[immunocompetent]] patients. While in [[immunocompromised]] patients, the disease is more prolonged and patients are more vulnerable to complications such as [[malnutrition]] and [[vitamin deficiencies]].<ref name="pmid17662322">{{cite journal |vauthors=van Hal SJ, Muthiah K, Matthews G, Harkness J, Stark D, Cooper D, Marriott D |title=Declining incidence of intestinal microsporidiosis and reduction in AIDS-related mortality following introduction of HAART in Sydney, Australia |journal=Trans. R. Soc. Trop. Med. Hyg. |volume=101 |issue=11 |pages=1096–100 |year=2007 |pmid=17662322 |doi=10.1016/j.trstmh.2007.06.003 |url=}}</ref> | |||
==Complications== | |||
Complications might arise in [[immunocompromised]] patients due to [[chronic diarrhea]]:<ref name="pmid24829239">{{cite journal |vauthors=Ramanan P, Pritt BS |title=Extraintestinal microsporidiosis |journal=J. Clin. Microbiol. |volume=52 |issue=11 |pages=3839–44 |year=2014 |pmid=24829239 |pmc=4313212 |doi=10.1128/JCM.00971-14 |url=}}</ref><ref name="pmid17662322">{{cite journal |vauthors=van Hal SJ, Muthiah K, Matthews G, Harkness J, Stark D, Cooper D, Marriott D |title=Declining incidence of intestinal microsporidiosis and reduction in AIDS-related mortality following introduction of HAART in Sydney, Australia |journal=Trans. R. Soc. Trop. Med. Hyg. |volume=101 |issue=11 |pages=1096–100 |year=2007 |pmid=17662322 |doi=10.1016/j.trstmh.2007.06.003 |url=}}</ref> | |||
*[[Dehydration]] | |||
*[[Weight loss]] | |||
*[[Nutritional deficiencies]] | |||
*[[Acalculous cholecystitis]] | |||
*Systemic spread to the [[brain]], [[respiratory tract]], [[urinary tract]], etc. | |||
== | ==Prognosis== | ||
*The prognosis is excellent among [[immunocompetent]] patients and the disease is self-limited within 2 weeks. | |||
*In [[immunocompromised]] patients, the prognosis is less favorable with more vulnerability to develop systemic spread of the disease and complications. | |||
*[[Mortality]] due to microsporidiosis is mostly associated with systemic disease and in [[AIDS]] patients not receiving [[HIV AIDS medical therapy|HAART]]. | |||
==References== | ==References== | ||
| Line 17: | Line 26: | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Digestive diseases]] | [[Category:Digestive diseases]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Needs content]] | [[Category:Needs content]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Latest revision as of 18:04, 18 September 2017
|
Microsporidiosis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Microsporidiosis natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Microsporidiosis natural history, complications and prognosis |
|
FDA on Microsporidiosis natural history, complications and prognosis |
|
CDC on Microsporidiosis natural history, complications and prognosis |
|
Microsporidiosis natural history, complications and prognosis in the news |
|
Blogs on Microsporidiosis natural history, complications and prognosis |
|
Risk calculators and risk factors for Microsporidiosis natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
If left untreated, immunocompetent patients resolve the disease completely within 2 weeks while immunocompromised patients might develop chronic diarrhea. Common complications of microsporidiosis include weight loss, dehydration, and acalculous cholecystitis. Prognosis is generally excellent in immunocompetent patients while immunocompromised patients are more vulnerable to developing chronic disease and complications.
Natural History
If left untreated, microsporidiosis is self-resolving with complete recovery within 14 days in immunocompetent patients. While in immunocompromised patients, the disease is more prolonged and patients are more vulnerable to complications such as malnutrition and vitamin deficiencies.[1]
Complications
Complications might arise in immunocompromised patients due to chronic diarrhea:[2][1]
- Dehydration
- Weight loss
- Nutritional deficiencies
- Acalculous cholecystitis
- Systemic spread to the brain, respiratory tract, urinary tract, etc.
Prognosis
- The prognosis is excellent among immunocompetent patients and the disease is self-limited within 2 weeks.
- In immunocompromised patients, the prognosis is less favorable with more vulnerability to develop systemic spread of the disease and complications.
- Mortality due to microsporidiosis is mostly associated with systemic disease and in AIDS patients not receiving HAART.
References
- ↑ 1.0 1.1 van Hal SJ, Muthiah K, Matthews G, Harkness J, Stark D, Cooper D, Marriott D (2007). "Declining incidence of intestinal microsporidiosis and reduction in AIDS-related mortality following introduction of HAART in Sydney, Australia". Trans. R. Soc. Trop. Med. Hyg. 101 (11): 1096–100. doi:10.1016/j.trstmh.2007.06.003. PMID 17662322.
- ↑ Ramanan P, Pritt BS (2014). "Extraintestinal microsporidiosis". J. Clin. Microbiol. 52 (11): 3839–44. doi:10.1128/JCM.00971-14. PMC 4313212. PMID 24829239.