Hyperparathyroidism ultrasound: Difference between revisions
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{{Hyperparathyroidism}} | {{Hyperparathyroidism}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{Anmol}} | ||
==Overview== | ==Overview== | ||
Neck ultrasound is used for preoperative localization of hyper-functioning [[parathyroid gland]]. Neck ultrasound alone is not a [[Sensitivity (tests)|sensitive]] investigation for this purpose. Neck ultrasound along with [[Tc-99m sestamibi scintigraphy]] is most common used diagnostic modality for preoperative localization of hyper-functioning [[parathyroid gland]]. | |||
* | ==Ultrasound== | ||
*Neck ultrasound is used for preoperative localization of hyper-functioning [[parathyroid gland]]. Neck ultrasound alone is not a [[Sensitivity (tests)|sensitive]] investigation for this purpose. <ref name="pmid12153604">{{cite journal |vauthors=Haber RS, Kim CK, Inabnet WB |title=Ultrasonography for preoperative localization of enlarged parathyroid glands in primary hyperparathyroidism: comparison with (99m)technetium sestamibi scintigraphy |journal=Clin. Endocrinol. (Oxf) |volume=57 |issue=2 |pages=241–9 |year=2002 |pmid=12153604 |doi= |url=}}</ref> | |||
* | *Neck ultrasound is an operator dependent method. | ||
*Neck ultrasound along with [[Tc-99m sestamibi scintigraphy]] is most common used diagnostic modality for preoperative localization of hyper-functioning [[parathyroid gland]].<ref name="pmid20566979">{{cite journal |vauthors=Elaraj DM, Sippel RS, Lindsay S, Sansano I, Duh QY, Clark OH, Kebebew E |title=Are additional localization studies and referral indicated for patients with primary hyperparathyroidism who have negative sestamibi scan results? |journal=Arch Surg |volume=145 |issue=6 |pages=578–81 |year=2010 |pmid=20566979 |doi=10.1001/archsurg.2010.108 |url=}}</ref> | |||
* | *Presence of [[thyroid nodule]] may lead to false positive results.<ref name="pmid19563934">{{cite journal |vauthors=Barbaros U, Erbil Y, Salmashoğlu A, Işsever H, Aral F, Tunaci M, Ozarmağan S |title=The characteristics of concomitant thyroid nodules cause false-positive ultrasonography results in primary hyperparathyroidism |journal=Am J Otolaryngol |volume=30 |issue=4 |pages=239–43 |year=2009 |pmid=19563934 |doi=10.1016/j.amjoto.2008.06.007 |url=}}</ref> | ||
*Ultrasound is the single most cost-effective method used for preoperative localization of hyper-functioning parathyroid gland followed by [[Hyperparathyroidism CT|4-dimentional CT]].<ref name="pmid22825773">{{cite journal |vauthors=Lubitz CC, Stephen AE, Hodin RA, Pandharipande P |title=Preoperative localization strategies for primary hyperparathyroidism: an economic analysis |journal=Ann. Surg. Oncol. |volume=19 |issue=13 |pages=4202–9 |year=2012 |pmid=22825773 |pmc=3680347 |doi=10.1245/s10434-012-2512-2 |url=}}</ref> | |||
*Surgeon performed ultrasound has a [[Sensitivity (tests)|sensitivity]] of 69% to 92.5%.<ref name="pmid16377493">{{cite journal |vauthors=Solorzano CC, Carneiro-Pla DM, Irvin GL |title=Surgeon-performed ultrasonography as the initial and only localizing study in sporadic primary hyperparathyroidism |journal=J. Am. Coll. Surg. |volume=202 |issue=1 |pages=18–24 |year=2006 |pmid=16377493 |doi=10.1016/j.jamcollsurg.2005.08.014 |url=}}</ref><ref name="pmid17685957">{{cite journal |vauthors=Prasannan S, Davies G, Bochner M, Kollias J, Malycha P |title=Minimally invasive parathyroidectomy using surgeon-performed ultrasound and sestamibi |journal=ANZ J Surg |volume=77 |issue=9 |pages=774–7 |year=2007 |pmid=17685957 |doi=10.1111/j.1445-2197.2007.04227.x |url=}}</ref><ref name="pmid8678959">{{cite journal |vauthors=Chapuis Y, Fulla Y, Bonnichon P, Tarla E, Abboud B, Pitre J, Richard B |title=Values of ultrasonography, sestamibi scintigraphy, and intraoperative measurement of 1-84 PTH for unilateral neck exploration of primary hyperparathyroidism |journal=World J Surg |volume=20 |issue=7 |pages=835–9; discussion 839–40 |year=1996 |pmid=8678959 |doi= |url=}}</ref><ref name="pmid8214295">{{cite journal |vauthors=Casas AT, Burke GJ, Sathyanarayana, Mansberger AR, Wei JP |title=Prospective comparison of technetium-99m-sestamibi/iodine-123 radionuclide scan versus high-resolution ultrasonography for the preoperative localization of abnormal parathyroid glands in patients with previously unoperated primary hyperparathyroidism |journal=Am. J. Surg. |volume=166 |issue=4 |pages=369–73 |year=1993 |pmid=8214295 |doi= |url=}}</ref> | |||
[[image:Parathyroid adenoma gif.gif|thumb|600px|center|Neck ultrasound showing parathyroid adenoma - [https://commons.wikimedia.org/wiki/File:Nebenschilddruesenadenom_Sonographie_rechts_transversal.jpg Source:By Hellerhoff (Own work), via Wikimedia Commons]]] | |||
==References== | ==References== | ||
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[[Category:Disease]] | |||
[[Category:Medicine]] | |||
[[Category:Endocrinology]] | |||
[[Category:Parathyroid disorders]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Radiology]] |
Latest revision as of 22:16, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]
Overview
Neck ultrasound is used for preoperative localization of hyper-functioning parathyroid gland. Neck ultrasound alone is not a sensitive investigation for this purpose. Neck ultrasound along with Tc-99m sestamibi scintigraphy is most common used diagnostic modality for preoperative localization of hyper-functioning parathyroid gland.
Ultrasound
- Neck ultrasound is used for preoperative localization of hyper-functioning parathyroid gland. Neck ultrasound alone is not a sensitive investigation for this purpose. [1]
- Neck ultrasound is an operator dependent method.
- Neck ultrasound along with Tc-99m sestamibi scintigraphy is most common used diagnostic modality for preoperative localization of hyper-functioning parathyroid gland.[2]
- Presence of thyroid nodule may lead to false positive results.[3]
- Ultrasound is the single most cost-effective method used for preoperative localization of hyper-functioning parathyroid gland followed by 4-dimentional CT.[4]
- Surgeon performed ultrasound has a sensitivity of 69% to 92.5%.[5][6][7][8]
![](/images/3/33/Parathyroid_adenoma_gif.gif)
References
- ↑ Haber RS, Kim CK, Inabnet WB (2002). "Ultrasonography for preoperative localization of enlarged parathyroid glands in primary hyperparathyroidism: comparison with (99m)technetium sestamibi scintigraphy". Clin. Endocrinol. (Oxf). 57 (2): 241–9. PMID 12153604.
- ↑ Elaraj DM, Sippel RS, Lindsay S, Sansano I, Duh QY, Clark OH, Kebebew E (2010). "Are additional localization studies and referral indicated for patients with primary hyperparathyroidism who have negative sestamibi scan results?". Arch Surg. 145 (6): 578–81. doi:10.1001/archsurg.2010.108. PMID 20566979.
- ↑ Barbaros U, Erbil Y, Salmashoğlu A, Işsever H, Aral F, Tunaci M, Ozarmağan S (2009). "The characteristics of concomitant thyroid nodules cause false-positive ultrasonography results in primary hyperparathyroidism". Am J Otolaryngol. 30 (4): 239–43. doi:10.1016/j.amjoto.2008.06.007. PMID 19563934.
- ↑ Lubitz CC, Stephen AE, Hodin RA, Pandharipande P (2012). "Preoperative localization strategies for primary hyperparathyroidism: an economic analysis". Ann. Surg. Oncol. 19 (13): 4202–9. doi:10.1245/s10434-012-2512-2. PMC 3680347. PMID 22825773.
- ↑ Solorzano CC, Carneiro-Pla DM, Irvin GL (2006). "Surgeon-performed ultrasonography as the initial and only localizing study in sporadic primary hyperparathyroidism". J. Am. Coll. Surg. 202 (1): 18–24. doi:10.1016/j.jamcollsurg.2005.08.014. PMID 16377493.
- ↑ Prasannan S, Davies G, Bochner M, Kollias J, Malycha P (2007). "Minimally invasive parathyroidectomy using surgeon-performed ultrasound and sestamibi". ANZ J Surg. 77 (9): 774–7. doi:10.1111/j.1445-2197.2007.04227.x. PMID 17685957.
- ↑ Chapuis Y, Fulla Y, Bonnichon P, Tarla E, Abboud B, Pitre J, Richard B (1996). "Values of ultrasonography, sestamibi scintigraphy, and intraoperative measurement of 1-84 PTH for unilateral neck exploration of primary hyperparathyroidism". World J Surg. 20 (7): 835–9, discussion 839–40. PMID 8678959.
- ↑ Casas AT, Burke GJ, Sathyanarayana, Mansberger AR, Wei JP (1993). "Prospective comparison of technetium-99m-sestamibi/iodine-123 radionuclide scan versus high-resolution ultrasonography for the preoperative localization of abnormal parathyroid glands in patients with previously unoperated primary hyperparathyroidism". Am. J. Surg. 166 (4): 369–73. PMID 8214295.