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==Overview==
==Overview==
Cretinism was first described by ancient Roman writers. In the 19th century, cretinism was described by [[Physician|physicians]] and travelers and some areas in Europe and North America were named as "[[goiter]] belts".


==Historical Perspective==
==Historical Perspective==


===Discovery===
===Discovery===
*[Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
*Cretinism was described by ancient Roman writers and they declared Southern Europe around the Alps as endemic areas.<ref name="pmid14023685">{{cite journal| author=CRANEFIELD PF| title=The discovery of cretinism. | journal=Bull Hist Med | year= 1962 | volume= 36 | issue=  | pages= 489-511 | pmid=14023685 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14023685  }}</ref>
 
*In 1848, the first study of [[goiter]] and cretinism was held in Italy to detect the [[goiter]] cases in the population.  
*The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
*In the 19th century, cretinism was described by [[physicians]] and travelers. They did not know the cause of cretinism and linked it to polluted air and water in the Alps mountains.
*In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
*In the 19th century, some areas in Europe and North America were named as "[[goiter]] belts".  
*In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
*In the 20th century, the relationships of sporadic cretinism with congenital hypothyroidism and of endemic cretinism with [[hypothyroidism]] due to [[Iodine deficiency|iodine deficienc]]<nowiki/>y were discovered.
 
==Outbreaks==
*There have been several outbreaks of [disease name], which are summarized below:
 
==Landmark Events in the Development of Treatment Strategies==
*In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
 
==Impact on Cultural History==
 
 
==Famous Cases==
*The following are a few famous cases of [[disease name]]:
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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[[Category:Medicine]]
[[Category:Endocrinology]]
[[Category:Up-To-Date]]
[[Category:Pediatrics]]

Latest revision as of 14:21, 30 October 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Cretinism was first described by ancient Roman writers. In the 19th century, cretinism was described by physicians and travelers and some areas in Europe and North America were named as "goiter belts".

Historical Perspective

Discovery

  • Cretinism was described by ancient Roman writers and they declared Southern Europe around the Alps as endemic areas.[1]
  • In 1848, the first study of goiter and cretinism was held in Italy to detect the goiter cases in the population.
  • In the 19th century, cretinism was described by physicians and travelers. They did not know the cause of cretinism and linked it to polluted air and water in the Alps mountains.
  • In the 19th century, some areas in Europe and North America were named as "goiter belts".
  • In the 20th century, the relationships of sporadic cretinism with congenital hypothyroidism and of endemic cretinism with hypothyroidism due to iodine deficiency were discovered.

References

  1. CRANEFIELD PF (1962). "The discovery of cretinism". Bull Hist Med. 36: 489–511. PMID 14023685.

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