Goiter physical examination: Difference between revisions

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{{Goiter}}
{{Goiter}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{ARK}}


==Overview==
==Overview==
Physical examination of patients with Goiter is usually remarkable for swelling at the base of the neck.
[[Physical examination]] of patients with goiter is usually remarkable for [[swelling]] at the base of the [[neck]].


==Physical Examination==
==Physical Examination==
*Physical examination of patients with Goiter is usually remarkable for swelling at the base of the neck
[[Physical examination]] of patients with goiter is usually remarkable for [[swelling]] at the base of the [[neck]].<ref name="pmid18664541">{{cite journal| author=Bonnema SJ, Nielsen VE, Boel-Jørgensen H, Grupe P, Andersen PB, Bastholt L et al.| title=Recombinant human thyrotropin-stimulated radioiodine therapy of large nodular goiters facilitates tracheal decompression and improves inspiration. | journal=J Clin Endocrinol Metab | year= 2008 | volume= 93 | issue= 10 | pages= 3981-4 | pmid=18664541 | doi=10.1210/jc.2008-0485 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18664541  }} </ref><ref name="pmid20823469">{{cite journal| author=Jukić T, Kusić Z| title=Image in endocrinology. Pemberton's sign in patient with substernal goiter. | journal=J Clin Endocrinol Metab | year= 2010 | volume= 95 | issue= 9 | pages= 4175 | pmid=20823469 | doi=10.1210/jc.2010-0944 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20823469  }} </ref>


===Appearance of the Patient===
===Appearance of the patient===
*Patients with Goiter usually appear with a cosmetic distortion of the neck along with a lump at the base of the neck and are asymptomatic in general.
*Patients with goiter usually appear with a cosmetic distortion of the [[neck]] along with a [[lump]] at the base of the [[neck]] and are [[asymptomatic]] in general.


===Vital Signs===
===Vital signs===
*[[Tachycardia]]
*[[Tachycardia]]


===Skin===
===Skin===
*Moist skin
*[[Moist skin]]


===HEENT===
===HEENT===
*Exophthalmosis
*[[Exophthalmos]]


===Neck===
===Neck===
*[[Jugular vein compression]] or [[thrombosis]] (Rare) <ref name="pmid4913941">{{cite journal |vauthors=Siderys H, Rowe GA |title=Superior vena caval syndrome caused by intrathoracic goiter |journal=Am Surg |volume=36 |issue=7 |pages=446–50 |year=1970 |pmid=4913941 |doi= |url=}}</ref>
*[[Jugular vein]] compression or [[thrombosis]] (rare) <ref name="pmid4913941">{{cite journal |vauthors=Siderys H, Rowe GA |title=Superior vena caval syndrome caused by intrathoracic goiter |journal=Am Surg |volume=36 |issue=7 |pages=446–50 |year=1970 |pmid=4913941 |doi= |url=}}</ref>
*[[Superior vena cava syndrome]] (Rare) <ref name="pmid4913941">{{cite journal |vauthors=Siderys H, Rowe GA |title=Superior vena caval syndrome caused by intrathoracic goiter |journal=Am Surg |volume=36 |issue=7 |pages=446–50 |year=1970 |pmid=4913941 |doi= |url=}}</ref>
*[[Superior vena cava syndrome]] (rare) <ref name="pmid4913941">{{cite journal |vauthors=Siderys H, Rowe GA |title=Superior vena caval syndrome caused by intrathoracic goiter |journal=Am Surg |volume=36 |issue=7 |pages=446–50 |year=1970 |pmid=4913941 |doi= |url=}}</ref>


===Lungs===
===Lungs===
*Normal vesicular breath sounds
*Normal [[Vesicular breathing|vesicular]] [[breath sounds]]
*[[Wheeze]] may be present as a result of compression of the gland over the trachea
*[[Wheeze]] may be present as a result of compression of the [[thyroid gland]] over the [[trachea]]
*[[Tracheal deviation]] or compression may be seen in some cases
*[[Tracheal deviation]] or compression may be seen in some cases
*[[Stridor]] may be seen in some cases
*[[Stridor]] may be seen in some cases


===Heart===
===Heart===
*Normal S1 and S2.
*Normal [[S1]] and [[S2]]
*No rubs or gallop


===Abdomen===
===Abdomen===
*Normal abdominal findings.
*Normal [[abdominal]] findings


===Back===
===Back===
Line 51: Line 52:


====Pemberton's sign====
====Pemberton's sign====
*While clinically evaluating an enlarged thyroid gland, pemberton's sign is observed. <ref name="pmid24646105">{{cite journal| author=De Filippis EA, Sabet A, Sun MR, Garber JR| title=Pemberton's sign: explained nearly 70 years later. | journal=J Clin Endocrinol Metab | year= 2014 | volume= 99 | issue= 6 | pages= 1949-54 | pmid=24646105 | doi=10.1210/jc.2013-4240 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24646105  }} </ref> <ref name="pmid24646105">{{cite journal| author=De Filippis EA, Sabet A, Sun MR, Garber JR| title=Pemberton's sign: explained nearly 70 years later. | journal=J Clin Endocrinol Metab | year= 2014 | volume= 99 | issue= 6 | pages= 1949-54 | pmid=24646105 | doi=10.1210/jc.2013-4240 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24646105 }} </ref> <ref name="pmid15044645">{{cite journal| author=Basaria S, Salvatori R| title=Images in clinical medicine. Pemberton's sign. | journal=N Engl J Med | year= 2004 | volume= 350 | issue= 13 | pages= 1338 | pmid=15044645 | doi=10.1056/NEJMicm990287 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15044645 }} </ref>  
*While clinically evaluating an [[enlarged thyroid gland]], [[Pemberton's sign]] is observed.<ref name="pmid24646105">{{cite journal| author=De Filippis EA, Sabet A, Sun MR, Garber JR| title=Pemberton's sign: explained nearly 70 years later. | journal=J Clin Endocrinol Metab | year= 2014 | volume= 99 | issue= 6 | pages= 1949-54 | pmid=24646105 | doi=10.1210/jc.2013-4240 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24646105  }} </ref><ref name="pmid15044645">{{cite journal| author=Basaria S, Salvatori R| title=Images in clinical medicine. Pemberton's sign. | journal=N Engl J Med | year= 2004 | volume= 350 | issue= 13 | pages= 1338 | pmid=15044645 | doi=10.1056/NEJMicm990287 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15044645 }} </ref><ref name="pmid9385120">{{cite journal| author=Anders H, Keller C| title=Pemberton's maneuver - a clinical test for latent superior vena cava syndrome caused by a substernal mass. | journal=Eur J Med Res | year= 1997 | volume= 2 | issue= 11 | pages= 488-90 | pmid=9385120 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9385120 }} </ref>
*Pemberton's sign is observed when both arms are elevated until the arms align with the side of the head. Usually in a minute of doing so, this elicits:
*[[Pemberton's sign]] is observed when both arms are elevated until the arms align with the side of the head. Usually in a minute of doing so, this elicits:
**Congestion of face
**Congestion of [[face]]
**Cyanosis
**[[Cyanosis]]
**Distress
**[[Distress]]
*Vascular engorgement and facial congestion imply the impaired venous outflow from the head and neck
*[[Vascular]] engorgement and facial [[congestion]] imply the impaired [[venous]] outflow from the [[head]] and [[neck]]
*Tracheal compromise may also be observed
*[[Trachea|Tracheal]] compression may also be observed
*Venous thrombosis has also been seen in few cases
*[[Venous thrombosis]] has also been seen in few cases


==References==
==References==

Latest revision as of 18:44, 17 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]

Overview

Physical examination of patients with goiter is usually remarkable for swelling at the base of the neck.

Physical Examination

Physical examination of patients with goiter is usually remarkable for swelling at the base of the neck.[1][2]

Appearance of the patient

  • Patients with goiter usually appear with a cosmetic distortion of the neck along with a lump at the base of the neck and are asymptomatic in general.

Vital signs

Skin

HEENT

Neck

Lungs

Heart

  • Normal S1 and S2
  • No rubs or gallop

Abdomen

Back

  • Normal findings observed

Genitourinary

  • Normal findings observed

Neuromuscular

Extremities

  • Normal findings observed

Pemberton's sign

References

  1. Bonnema SJ, Nielsen VE, Boel-Jørgensen H, Grupe P, Andersen PB, Bastholt L; et al. (2008). "Recombinant human thyrotropin-stimulated radioiodine therapy of large nodular goiters facilitates tracheal decompression and improves inspiration". J Clin Endocrinol Metab. 93 (10): 3981–4. doi:10.1210/jc.2008-0485. PMID 18664541.
  2. Jukić T, Kusić Z (2010). "Image in endocrinology. Pemberton's sign in patient with substernal goiter". J Clin Endocrinol Metab. 95 (9): 4175. doi:10.1210/jc.2010-0944. PMID 20823469.
  3. 3.0 3.1 Siderys H, Rowe GA (1970). "Superior vena caval syndrome caused by intrathoracic goiter". Am Surg. 36 (7): 446–50. PMID 4913941.
  4. De Filippis EA, Sabet A, Sun MR, Garber JR (2014). "Pemberton's sign: explained nearly 70 years later". J Clin Endocrinol Metab. 99 (6): 1949–54. doi:10.1210/jc.2013-4240. PMID 24646105.
  5. Basaria S, Salvatori R (2004). "Images in clinical medicine. Pemberton's sign". N Engl J Med. 350 (13): 1338. doi:10.1056/NEJMicm990287. PMID 15044645.
  6. Anders H, Keller C (1997). "Pemberton's maneuver - a clinical test for latent superior vena cava syndrome caused by a substernal mass". Eur J Med Res. 2 (11): 488–90. PMID 9385120.

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