Delayed puberty classification: Difference between revisions
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==Overview== | ==Overview== | ||
Delayed puberty is almost always due to [[physiologic]] | Delayed puberty is almost always due to [[physiologic]] exaggeration of the prolongation of [[puberty]] timing; a condition called [[Constitutional delay of puberty|constitutional delay of growth and puberty (CDGP)]]. Other forms of delayed puberty include hypergonadotropic [[hypogonadism]], permanent [[hypogonadotropic hypogonadism]], and functional [[hypogonadotropic hypogonadism]]. | ||
==Classification== | ==Classification== | ||
* Delayed puberty may be classified according to etiology into 4 subtypes | * Delayed puberty may be classified according to etiology into 4 subtypes which includes:<ref name="PalmertDunkel2012">{{cite journal|last1=Palmert|first1=Mark R.|last2=Dunkel|first2=Leo|title=Delayed Puberty|journal=New England Journal of Medicine|volume=366|issue=5|year=2012|pages=443–453|issn=0028-4793|doi=10.1056/NEJMcp1109290}}</ref> | ||
**[[Constitutional delay of puberty|Constitutional delay of growth and puberty (CDGP)]] | |||
**Hypergonadotropic [[hypogonadism]] | |||
**Permanent [[hypogonadotropic hypogonadism]] | |||
**Functional [[hypogonadotropic hypogonadism]] | |||
* The most common subtype of delayed puberty, [[Constitutional delay of puberty|constitutional delay of growth and puberty (CDGP)]], has no pathological etiology and is completely physiologic. | * The most common subtype of delayed puberty, [[Constitutional delay of puberty|constitutional delay of growth and puberty (CDGP)]], has no pathological etiology and is completely physiologic. | ||
* Other subtypes of delayed puberty are classified upon the serum levels of [[sex hormones]] and also [[gonadotropins]]. | * Other subtypes of delayed puberty are classified upon the serum levels of [[sex hormones]] and also [[gonadotropins]]. | ||
* The complete classification of delayed puberty is as follows: | * The complete classification of delayed puberty is as follows: | ||
{{Family tree/start}} | {{Family tree/start}} | ||
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{{Family tree | | | |!| | | | E01 | | | E02 | | | E03 | | | |E01= Hypergonadotropic [[hypogonadism]]<br>(primary [[hypogonadism]])|E02=Permanent [[hypogonadotropic hypogonadism]]<br>(secondary [[hypogonadism]])|E03=Transient [[hypogonadotropic hypogonadism]]<br>(functional [[hypogonadism]])}} | {{Family tree | | | |!| | | | E01 | | | E02 | | | E03 | | | |E01= Hypergonadotropic [[hypogonadism]]<br>(primary [[hypogonadism]])|E02=Permanent [[hypogonadotropic hypogonadism]]<br>(secondary [[hypogonadism]])|E03=Transient [[hypogonadotropic hypogonadism]]<br>(functional [[hypogonadism]])}} | ||
{{Family tree | | | |!| | | | |`|-|-|-|-|+|-|-|-|-|'| | | | | |}} | {{Family tree | | | |!| | | | |`|-|-|-|-|+|-|-|-|-|'| | | | | |}} | ||
{{Family tree | | | C01 | | | | | | | | C02 | | | | | | |C01= [[image:Flow diagram showing normal hormonal control of puberty.gif|thumb|Diagram showing normal hormonal control of puberty, via Wikimedia.org - By Neil Smith <ref name="http://creativecommons.org/licenses/by-sa/3.0">CC BY-SA 3.0> "https://commons.wikimedia.org/wiki/File%3AFlow_diagram_showing_normal_hormonal_control_of_puberty.gif">via Wikimedia Commons</ref>]]| C02=[[image:Diagram showing the disruption of the hormonal pathways of puberty due to the failure of GnRH release seen in KS and HH.gif|thumb|Diagram showing the disruption of the hormonal pathways of puberty, via Wikimedia.org - By Neil Smith <ref name="http://creativecommons.org/licenses/by-sa/3.0">CC BY-SA 3.0>"https://commons.wikimedia.org/wiki/File%3ADiagram_showing_the_disruption_of_the_hormonal_pathways_of_puberty_due_to_the_failure_of_GnRH_release_seen_in_KS_and_HH.gif">via Wikimedia Commons</ref>]]}} | {{Family tree | | | C01 | | | | | | | | C02 | | | | | | |C01= [[image:Flow diagram showing normal hormonal control of puberty.gif|thumb|Diagram showing normal hormonal control of puberty, via Wikimedia.org - By Neil Smith, via Wikimedia Commons<ref name="http://creativecommons.org/licenses/by-sa/3.0">CC BY-SA 3.0> "https://commons.wikimedia.org/wiki/File%3AFlow_diagram_showing_normal_hormonal_control_of_puberty.gif">via Wikimedia Commons</ref>]]| C02=[[image:Diagram showing the disruption of the hormonal pathways of puberty due to the failure of GnRH release seen in KS and HH.gif|thumb|Diagram showing the disruption of the hormonal pathways of puberty, via Wikimedia.org - By Neil Smith, via Wikimedia Commons<ref name="http://creativecommons.org/licenses/by-sa/3.0">CC BY-SA 3.0>"https://commons.wikimedia.org/wiki/File%3ADiagram_showing_the_disruption_of_the_hormonal_pathways_of_puberty_due_to_the_failure_of_GnRH_release_seen_in_KS_and_HH.gif">via Wikimedia Commons</ref>]]}} | ||
{{Family tree/end}} | {{Family tree/end}} | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
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{{WH}} | |||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Medicine]] | |||
[[Category:Pediatrics]] | |||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Mature chapter]] | |||
[[Category:Developmental biology]] | |||
[[Category:Sexuality and age]] | |||
[[Category:Sexual health]] | |||
[[Category:Growth disorders]] | |||
[[Category:Congenital disorders]] | |||
[[Category:Up-To-Date]] | |||
Latest revision as of 21:15, 29 July 2020
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Delayed puberty Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Delayed puberty classification On the Web |
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American Roentgen Ray Society Images of Delayed puberty classification |
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Risk calculators and risk factors for Delayed puberty classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]
Overview
Delayed puberty is almost always due to physiologic exaggeration of the prolongation of puberty timing; a condition called constitutional delay of growth and puberty (CDGP). Other forms of delayed puberty include hypergonadotropic hypogonadism, permanent hypogonadotropic hypogonadism, and functional hypogonadotropic hypogonadism.
Classification
- Delayed puberty may be classified according to etiology into 4 subtypes which includes:[1]
- Constitutional delay of growth and puberty (CDGP)
- Hypergonadotropic hypogonadism
- Permanent hypogonadotropic hypogonadism
- Functional hypogonadotropic hypogonadism
- The most common subtype of delayed puberty, constitutional delay of growth and puberty (CDGP), has no pathological etiology and is completely physiologic.
- Other subtypes of delayed puberty are classified upon the serum levels of sex hormones and also gonadotropins.
- The complete classification of delayed puberty is as follows:
| Delayed puberty classification | |||||||||||||||||||||||||||||||||||||||||||||||||
| LH, FSH, and GnRH plasma level | |||||||||||||||||||||||||||||||||||||||||||||||||
| Normal | Abnormal | ||||||||||||||||||||||||||||||||||||||||||||||||
| Constitutional delay of growth and puberty (CDGP) | LH and FSH increased GnRH increased | LH and FSH decreased GnRH decreased | LH and FSH decreased GnRH decreased (transient) | ||||||||||||||||||||||||||||||||||||||||||||||
| Hypergonadotropic hypogonadism (primary hypogonadism) | Permanent hypogonadotropic hypogonadism (secondary hypogonadism) | Transient hypogonadotropic hypogonadism (functional hypogonadism) | |||||||||||||||||||||||||||||||||||||||||||||||
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References
- ↑ Palmert, Mark R.; Dunkel, Leo (2012). "Delayed Puberty". New England Journal of Medicine. 366 (5): 443–453. doi:10.1056/NEJMcp1109290. ISSN 0028-4793.
- ↑ 2.0 2.1 CC BY-SA 3.0> "https://commons.wikimedia.org/wiki/File%3AFlow_diagram_showing_normal_hormonal_control_of_puberty.gif">via Wikimedia Commons
