Endometrial cancer classification: Difference between revisions
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{{Endometrial cancer}} | {{Endometrial cancer}} | ||
{{CMG}}{{AE}}{{ | {{CMG}}{{AE}}{{RAK}} | ||
==Overview== | ==Overview== | ||
Endometrial cancer may be classified according to histology into | Endometrial cancer may be classified according to histology into either type I comprising 80% of endometrial cancers or type II accounting for around 20%. | ||
==Classification== | ==Classification== | ||
Endometrial cancer may be classified according to histology into 2 types:<ref name="pmid6822361">{{cite journal| author=Bokhman JV| title=Two pathogenetic types of endometrial carcinoma. | journal=Gynecol Oncol | year= 1983 | volume= 15 | issue= 1 | pages= 10-7 | pmid=6822361 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6822361 }} </ref> | |||
{| class="wikitable" | |||
: | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Type | ||
: | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Histology | ||
=== | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Prognosis | ||
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Pathogenesis | |||
: | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Prevalence | ||
:: | |- | ||
:: | | style="background:#DCDCDC;" align="center" + |Type I | ||
| style="background:#F5F5F5;" align="center" + |Endometroid (adenocarcinoma) | |||
: | | style="background:#F5F5F5;" align="center" + |Favorable (estrogen-responsive) | ||
: | | style="background:#F5F5F5;" align="left" + |• May arise from atypical hyperplasia <br> • Linked to unopposed estrogen stimulation | ||
: | | style="background:#F5F5F5;" align="center" + |80% | ||
: | |- | ||
: | | style="background:#DCDCDC;" align="center" + |Type II | ||
: | | style="background:#F5F5F5;" align="left" + |• Endometroid <br>• Serous <br>• Clear cell <br>• Mucinous <br>• Squamous <br>• Mesonephric <br>• Undifferentiated | ||
: | | style="background:#F5F5F5;" align="center" + |Typically bad prognosis | ||
: | | style="background:#F5F5F5;" align="left" + |• Develops from atrophic endometrium <br>• Not linked to hormonally driven pathogenesis | ||
| style="background:#F5F5F5;" align="center" + |15-20% | |||
|} | |||
==References== | ==References== | ||
Latest revision as of 18:41, 26 November 2018
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Endometrial cancer classification On the Web |
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Risk calculators and risk factors for Endometrial cancer classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Roukoz A. Karam, M.D.[2]
Overview
Endometrial cancer may be classified according to histology into either type I comprising 80% of endometrial cancers or type II accounting for around 20%.
Classification
Endometrial cancer may be classified according to histology into 2 types:[1]
| Type | Histology | Prognosis | Pathogenesis | Prevalence |
|---|---|---|---|---|
| Type I | Endometroid (adenocarcinoma) | Favorable (estrogen-responsive) | • May arise from atypical hyperplasia • Linked to unopposed estrogen stimulation |
80% |
| Type II | • Endometroid • Serous • Clear cell • Mucinous • Squamous • Mesonephric • Undifferentiated |
Typically bad prognosis | • Develops from atrophic endometrium • Not linked to hormonally driven pathogenesis |
15-20% |
References
- ↑ Bokhman JV (1983). "Two pathogenetic types of endometrial carcinoma". Gynecol Oncol. 15 (1): 10–7. PMID 6822361.