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__NOTOC__
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{{Gastric dumping syndrome}}
{{Gastric dumping syndrome}}
{{CMG}}
{{CMG}}; {{AE}} {{UA}}


==Overview==
==Overview==
The majority of patients with [disease name] are asymptomatic.
The history of [[Gastric dumping syndrome|dumping syndrome]] has to do with [[Surgery|surgeries]] or [[Disease|diseases]] that alter the [[motility]] or capacity of the [[stomach]]. The most common history of dumping syndrome is a [[bariatric surgery]] history. The most common [[Symptom|symptoms]] of [[Gastric dumping syndrome|dumping syndrome]] are [[diarrhea|diarrhea,]] [[Syncope|fainting]], [[syncope]], [[unconsciousness]], [[desire]] to lay down or sit down, [[Dyspnea|breathlessness]], [[dyspnea]], weakness, [[Fatigue|exhaustion]], [[Somnolence|sleepiness]], [[Somnolence|drowsiness]], [[apathy]], falling  asleep, [[palpitation]], [[Agitation (emotion)|restlessness]], [[dizziness]] and [[shock]].


OR
==History ==
The common surgical, medical and social history findings associated with dumping syndrome include:<ref name="pmid17643905">{{cite journal |vauthors=Tack J |title=Gastric motor disorders |journal=Best Pract Res Clin Gastroenterol |volume=21 |issue=4 |pages=633–44 |year=2007 |pmid=17643905 |doi=10.1016/j.bpg.2007.04.001 |url=}}</ref><ref name="pmid830568">{{cite journal |vauthors=MacGregor I, Parent J, Meyer JH |title=Gastric emptying of liquid meals and pancreatic and biliary secretion after subtotal gastrectomy or truncal vagotomy and pyloroplasty in man |journal=Gastroenterology |volume=72 |issue=2 |pages=195–205 |year=1977 |pmid=830568 |doi= |url=}}</ref><ref name="pmid6919504">{{cite journal |vauthors=Mayer EA, Thompson JB, Jehn D, Reedy T, Elashoff J, Meyer JH |title=Gastric emptying and sieving of solid food and pancreatic and biliary secretion after solid meals in patients with truncal vagotomy and antrectomy |journal=Gastroenterology |volume=83 |issue=1 Pt 2 |pages=184–92 |year=1982 |pmid=6919504 |doi= |url=}}</ref><ref name="pmid9200302">{{cite journal |vauthors=Vecht J, Masclee AA, Lamers CB |title=The dumping syndrome. Current insights into pathophysiology, diagnosis and treatment |journal=Scand. J. Gastroenterol. Suppl. |volume=223 |issue= |pages=21–7 |year=1997 |pmid=9200302 |doi= |url=}}</ref>


The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
===='''Surgical history'''====
The following [[Surgery|surgical]] procedures are associated with an increased risk of developing dumping syndrome:
*[[Gastrectomy]] (partial and total)
*[[Esophagectomy]]
*Billroth I [[gastroduodenostomy]]
*Billroth II [[gastrojejunostomy]]
*[[Roux-en-Y]] [[gastric bypass surgery]]
*Antiulcer [[surgery]] ([[vagotomy]])
*Antireflux [[surgery]] ([[Nissen fundoplication]], especially in [[Pediatrics|pediatric]] patients)
*[[Cholecystectomy]]
*[[Pyloromyotomy]]
*[[Esophageal]] repair of [[esophageal atresia]]
*[[Laparoscopic surgery|Laparoscopic]] sleeve [[gastrectomy]] (LSG)


==History and Symptoms==
====Medical History====
*The majority of patients with [disease name] are asymptomatic.
Patients suffering from the following diseases are more prone to develop dumping syndrome:
OR
*[[Diabetes mellitus|Diabetes Mellitus]]
*The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
*[[Zollinger-Ellison syndrome]]
*Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 
*[[Ehlers-Danlos syndrome]]
*[[Peptic ulcer|Duodenal ulcer]]
*[[Exocrine gland|Exocrine]] [[Pancreatic insufficiency]]
====Social History====
The following post-surgical diet is associated with dumping syndrome:
*High [[carbohydrate]] ([[sugar]]) intake
== Symptoms ==
[[Symptom|Symptoms]] of [[Gastric dumping syndrome|dumping syndrome]] include [[diarrhea]], [[Syncope|fainting]], [[Palpitation|palpitations]], [[fatigue]], [[bloating]] as well as many others. The [[Symptom|symptoms]] can be subdivided as follows:<ref name="urlPhase II Study Evaluating Efficacy, Safety and Pharmacokinetics of Pasireotide in Patients With Dumping Syndrome - Full Text View - ClinicalTrials.gov">{{cite web |url=https://www.clinicaltrials.gov/ct2/show/NCT01637272?term=NCT01637272 |title=Phase II Study Evaluating Efficacy, Safety and Pharmacokinetics of Pasireotide in Patients With Dumping Syndrome - Full Text View - ClinicalTrials.gov |format= |work= |accessdate=}}</ref><ref name="pmid5507449">{{cite journal |vauthors=Sigstad H |title=A clinical diagnostic index in the diagnosis of the dumping syndrome. Changes in plasma volume and blood sugar after a test meal |journal=Acta Med Scand |volume=188 |issue=6 |pages=479–86 |year=1970 |pmid=5507449 |doi= |url=}}</ref><ref name="pmid20829078">{{cite journal |vauthors=Mine S, Sano T, Tsutsumi K, Murakami Y, Ehara K, Saka M, Hara K, Fukagawa T, Udagawa H, Katai H |title=Large-scale investigation into dumping syndrome after gastrectomy for gastric cancer |journal=J. Am. Coll. Surg. |volume=211 |issue=5 |pages=628–36 |year=2010 |pmid=20829078 |doi=10.1016/j.jamcollsurg.2010.07.003 |url=}}</ref>


===History===
{| class="wikitable" style="margin: 1em auto 1em auto"
Patients with dumping syndrome may have a prior history of surgery.
|+ '''Symptom classification by Early Dumping or Late Dumping'''
! colspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" + | Early dumping
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Late dumping
|-
|'''Abdominal'''
|'''Vasomotor/Systemic'''
| rowspan="2" valign="top" |
* [[Tremor]]
* [[Hunger]]
* [[Perspiration]]
* Difficulty [[Concentration|concentrating]]
* Decreased [[consciousness]]
|-
| valign="top" |
* [[Nausea and vomiting|Nausea]]
* [[Diarrhea]]
* [[Nausea and vomiting|Vomiting]]
* [[Bloating]]
* [[Borborygmus|Borborygmi]]
* [[Epigastric]] [[Satiety|fullness]]
| valign="top" |
* [[Pallor]]
* [[Fatigue]]
* [[Flushing]]
* [[Syncope]]
* [[Headache]]
* [[Diaphoresis]]
* [[Palpitation|Palpitations]]
* [[Lightheadedness and vertigo|Lightheadedness]]
* [[Desire]] to lie down
|}


===Common Symptoms===
{| class="wikitable" style="margin: 1em auto 1em auto"
According to Sigstad's score, common symptoms of dumping syndrome include:
|+ '''Symptom classification by Sigstad's Score'''
*Shock
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Most common
*Fainting
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Less common
*Syncope
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Least common
*Unconsciousness
|-
*Desire to lay down or sit down
|
*Breathlessness
*[[Shock]]
*Dyspnea
*[[Syncope|Fainting]]
*[[Syncope]]
*[[Unconsciousness]]
*[[Desire]] to lay down or sit down
*[[Dyspnea|Breathlessness]]
*[[Dyspnea]]
*Weakness
*Weakness
*Exhaustion
*[[Fatigue|Exhaustion]]
*Sleepiness
*[[Somnolence|Sleepiness]]
*Drowsiness
*[[Somnolence|Drowsiness]]
*Apathy
*[[Apathy]]
*Falling asleep
*Falling asleep
*Palpation
*[[Palpitation]]
*Restlessness
*[[Agitation (emotion)|Restlessness]]
*Dizziness
*[[Dizziness]]
 
| valign="top" |
===Less Common Symptoms===
*[[Headache|Headaches]]
According to Sigstad's score, less common symptoms of dumping syndrome include:
*Headaches
*Feeling of warmth
*Feeling of warmth
*Sweating
*[[Perspiration|Sweating]]
*Pallor
*[[Pallor]]
*Clammy skin
*[[Clammy]] [[skin]]
*Nausea
*[[Nausea and vomiting|Nausea]]
*Abdominal fullness
*[[Abdomen|Abdominal]] [[Satiety|fullness]]
*Meteorism
*[[Tympanites|Meteorism]]
*Borborygmus
*[[Borborygmus]]
 
| valign="top" |
===Least common symptoms===
*[[Burping|Eructation]]
*Eructation
*[[Nausea and vomiting|Vomiting]]
*Vomiting
|}


==References==
==References==

Latest revision as of 16:55, 18 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Umar Ahmad, M.D.[2]

Overview

The history of dumping syndrome has to do with surgeries or diseases that alter the motility or capacity of the stomach. The most common history of dumping syndrome is a bariatric surgery history. The most common symptoms of dumping syndrome are diarrhea, fainting, syncope, unconsciousness, desire to lay down or sit down, breathlessness, dyspnea, weakness, exhaustion, sleepiness, drowsiness, apathy, falling asleep, palpitation, restlessness, dizziness and shock.

History

The common surgical, medical and social history findings associated with dumping syndrome include:[1][2][3][4]

Surgical history

The following surgical procedures are associated with an increased risk of developing dumping syndrome:

Medical History

Patients suffering from the following diseases are more prone to develop dumping syndrome:

Social History

The following post-surgical diet is associated with dumping syndrome:

Symptoms

Symptoms of dumping syndrome include diarrhea, fainting, palpitations, fatigue, bloating as well as many others. The symptoms can be subdivided as follows:[5][6][7]

Symptom classification by Early Dumping or Late Dumping
Early dumping Late dumping
Abdominal Vasomotor/Systemic
Symptom classification by Sigstad's Score
Most common Less common Least common

References

  1. ↑ Tack J (2007). "Gastric motor disorders". Best Pract Res Clin Gastroenterol. 21 (4): 633–44. doi:10.1016/j.bpg.2007.04.001. PMID 17643905.
  2. ↑ MacGregor I, Parent J, Meyer JH (1977). "Gastric emptying of liquid meals and pancreatic and biliary secretion after subtotal gastrectomy or truncal vagotomy and pyloroplasty in man". Gastroenterology. 72 (2): 195–205. PMID 830568.
  3. ↑ Mayer EA, Thompson JB, Jehn D, Reedy T, Elashoff J, Meyer JH (1982). "Gastric emptying and sieving of solid food and pancreatic and biliary secretion after solid meals in patients with truncal vagotomy and antrectomy". Gastroenterology. 83 (1 Pt 2): 184–92. PMID 6919504.
  4. ↑ Vecht J, Masclee AA, Lamers CB (1997). "The dumping syndrome. Current insights into pathophysiology, diagnosis and treatment". Scand. J. Gastroenterol. Suppl. 223: 21–7. PMID 9200302.
  5. ↑ "Phase II Study Evaluating Efficacy, Safety and Pharmacokinetics of Pasireotide in Patients With Dumping Syndrome - Full Text View - ClinicalTrials.gov".
  6. ↑ Sigstad H (1970). "A clinical diagnostic index in the diagnosis of the dumping syndrome. Changes in plasma volume and blood sugar after a test meal". Acta Med Scand. 188 (6): 479–86. PMID 5507449.
  7. ↑ Mine S, Sano T, Tsutsumi K, Murakami Y, Ehara K, Saka M, Hara K, Fukagawa T, Udagawa H, Katai H (2010). "Large-scale investigation into dumping syndrome after gastrectomy for gastric cancer". J. Am. Coll. Surg. 211 (5): 628–36. doi:10.1016/j.jamcollsurg.2010.07.003. PMID 20829078.

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