Esophageal cancer secondary prevention: Difference between revisions

Jump to navigation Jump to search
No edit summary
 
(7 intermediate revisions by 3 users not shown)
Line 1: Line 1:
{{Esophageal cancer}}
{{Esophageal cancer}}
{{CMG}};{{AE}} {{HM}}
{{CMG}}; {{AE}} {{HM}}


==Overview==
==Overview==
Secondary prevention may be effective in reducing the incidence of esophageal cancer, if treated early at the dysplasia stage with monoclonal antibody therapy. At present, there is no particular program in place to reduce the incidence of esophageal cancer.
Secondary prevention may be effective in reducing the [[incidence]] of esophageal cancer, if treated early at the [[dysplasia]] stage with [[Monoclonal antibodies|monoclonal antibody]] therapy. At present, there is no particular program in place to reduce the incidence of esophageal cancer.


==Secondary Prevention==
==Secondary Prevention==
*Secondary prevention can be effective in high risk groups whom frequently smoke and drink alcohol if they are treated early enough in the dysplastic change before cancer occurs.<ref name="pmid3219974">{{cite journal |vauthors=Lin PZ, Zhang JS, Cao SG, Rong ZP, Gao RQ, Han R, Shu SP |title=[Secondary prevention of esophageal cancer--intervention on precancerous lesions of the esophagus] |language=Chinese |journal=Zhonghua Zhong Liu Za Zhi |volume=10 |issue=3 |pages=161–6 |year=1988 |pmid=3219974 |doi= |url=}}</ref>
Secondary prevention can be effective in high risk groups with advanced [[dysplasia]] if they are treated (with monoclonal antibodies) early enough in the dysplastic phase before cancer occurs.<ref name="pmid3219974">{{cite journal |vauthors=Lin PZ, Zhang JS, Cao SG, Rong ZP, Gao RQ, Han R, Shu SP |title=[Secondary prevention of esophageal cancer--intervention on precancerous lesions of the esophagus] |language=Chinese |journal=Zhonghua Zhong Liu Za Zhi |volume=10 |issue=3 |pages=161–6 |year=1988 |pmid=3219974 |doi= |url=}}</ref>
*A study was carried out in Hishun village, China.  
*A high risk group who frequently smoke and drink alcohol were identified in Hishun village, China.
*Due to different dietary factors, the incidence of esophageal cancer amongst these people was particularly high.
*They were examined by esophageal exfoliative cytology.
*Subjects were examined by esophageal exfoliative cytology
*One third of the participants were found to have advanced esophageal [[dysplasia]].  
*One thrid of the participants had marked dysplasia  
*They were placed on an antitumor B regimen for 3 years.
* antitumor B (Chinese herbs); retinamide (4-Ethoxycarbophenylretinamide) and placebo.
*Patients who were treated with monoclonal antibodies subsequently showed a reduction in the incidence of esophageal cancer by 53%.
*The subjects with mild dysplasia were randomly divided  into 2 groups for treatment with riboflavin and placebo.  
*These results demonstrate the effectiveness of secondary prevention in the prevention of esophageal cancer.
*They were placed on antitumor B for 3 years  
*The incidence of esophageal cancer in the antitumor B group was reduced by 53% as compared with that of the placebo group (8.3%).  
*These results demonstrated that the secondary prevention of esophageal cancer is effective in the prevention of esophageal cancer.


==References==
==References==

Latest revision as of 16:48, 5 January 2018

Esophageal cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Differentiating Esophageal cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Esophageal cancer secondary prevention On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Esophageal cancer secondary prevention

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Esophageal cancer secondary prevention

CDC on Esophageal cancer secondary prevention

Esophageal cancer secondary prevention in the news

Blogs on Esophageal cancer secondary prevention

Directions to Hospitals Treating Esophageal cancer

Risk calculators and risk factors for Esophageal cancer secondary prevention

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

Secondary prevention may be effective in reducing the incidence of esophageal cancer, if treated early at the dysplasia stage with monoclonal antibody therapy. At present, there is no particular program in place to reduce the incidence of esophageal cancer.

Secondary Prevention

Secondary prevention can be effective in high risk groups with advanced dysplasia if they are treated (with monoclonal antibodies) early enough in the dysplastic phase before cancer occurs.[1]

  • A high risk group who frequently smoke and drink alcohol were identified in Hishun village, China.
  • They were examined by esophageal exfoliative cytology.
  • One third of the participants were found to have advanced esophageal dysplasia.
  • They were placed on an antitumor B regimen for 3 years.
  • Patients who were treated with monoclonal antibodies subsequently showed a reduction in the incidence of esophageal cancer by 53%.
  • These results demonstrate the effectiveness of secondary prevention in the prevention of esophageal cancer.

References

  1. Lin PZ, Zhang JS, Cao SG, Rong ZP, Gao RQ, Han R, Shu SP (1988). "[Secondary prevention of esophageal cancer--intervention on precancerous lesions of the esophagus]". Zhonghua Zhong Liu Za Zhi (in Chinese). 10 (3): 161–6. PMID 3219974.


Template:WikiDoc Sources