Hamman-Rich syndrome medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
There is no effective treatment for acute interstitial pneumonitis, includes supportive therapy and glucocorticosteroids. | There is no effective treatment for [[Hamman-Rich syndrome|acute interstitial pneumonitis]], Management in general includes supportive therapy and administration of glucocorticosteroids and Immunosuppressive agents. | ||
==Supportive care== | ==Supportive care== | ||
*Patients with acute interstitial pneumonitis receive supportive care alongside the medical therapy: | *Patients with [[Hamman-Rich syndrome|acute interstitial pneumonitis]] receive supportive care alongside the medical therapy<ref name="pmid16537878">{{cite journal |vauthors=Suh GY, Kang EH, Chung MP, Lee KS, Han J, Kitaichi M, Kwon OJ |title=Early intervention can improve clinical outcome of acute interstitial pneumonia |journal=Chest |volume=129 |issue=3 |pages=753–61 |date=March 2006 |pmid=16537878 |doi=10.1378/chest.129.3.753 |url=}}</ref>: | ||
**Supplemental oxygen | **Supplemental [[oxygen]] | ||
**Mechanical ventilation | **[[Mechanical ventilation]] | ||
**Measures to be taken to relieve [[Symptom|symptoms]] (eg, [[dyspnea]], [[anxiety]], [[cough]]) | |||
**Prevention of complications | **Prevention of complications | ||
***Venous thromboembolism | ***[[Venous thromboembolism]] | ||
***Gastrointestinal bleeding | ***[[Gastrointestinal bleeding]] | ||
*** Hospital-acquired pneumonia | *** [[Hospital-acquired pneumonia]] | ||
***Sepsis | *** Secondary [[pulmonary hypertension]] | ||
*Pulmonary rehabilitation | *** [[Anemia]] | ||
*Vaccination against possible causes of pulmonary inflammation as influenza and pneumococcal | ***[[Sepsis]] | ||
*Pulmonary rehabilitation (eg, patient education, optimal exercise program) | |||
*Maintain ideal body-mass index | |||
**Reduction of weight if obese | |||
**Nutritional support if the patient is cachectic | |||
*[[Vaccination]] against possible causes of pulmonary inflammation as [[influenza]] and [[Streptococcus pneumoniae|pneumococca]]<nowiki/>l vaccines.<ref name="pmid25233284">{{cite journal |vauthors=Tomczyk S, Bennett NM, Stoecker C, Gierke R, Moore MR, Whitney CG, Hadler S, Pilishvili T |title=Use of 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine among adults aged ≥65 years: recommendations of the Advisory Committee on Immunization Practices (ACIP) |journal=MMWR Morb. Mortal. Wkly. Rep. |volume=63 |issue=37 |pages=822–5 |date=September 2014 |pmid=25233284 |pmc=5779453 |doi= |url=}}</ref> | |||
==Medical Therapy== | ==Medical Therapy== | ||
*Corticosteroid therapy: | *Corticosteroid therapy:<ref name="pmid19095855">{{cite journal |vauthors=Avnon LS, Pikovsky O, Sion-Vardy N, Almog Y |title=Acute interstitial pneumonia-Hamman-Rich syndrome: clinical characteristics and diagnostic and therapeutic considerations |journal=Anesth. Analg. |volume=108 |issue=1 |pages=232–7 |date=January 2009 |pmid=19095855 |doi=10.1213/ane.0b013e318188af7a |url=}}</ref> | ||
**Once the diagnosis of acute interstitial pneumonitis is confirmed, high doses of glucocorticosteroids (eg, methylprednisolone) should be administered. | **Once the [[diagnosis]] of [[Hamman-Rich syndrome|acute interstitial pneumonitis]] is confirmed, high doses of [[Steroid|glucocorticosteroids]] (eg, [[methylprednisolone]]) should be administered. | ||
**Monitor the patient for glucocorticosteroid-induced side effects (eg, hyperglycemia, increased susceptibility to infection, gastritis). | **Monitor the patient for glucocorticosteroid-induced side effects (eg, [[hyperglycemia]], increased susceptibility to [[infection]], [[gastritis]]). | ||
*Immunosuppressive therapy | *Immunosuppressive therapy | ||
==References== | |||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Pulmonology]] | [[Category:Pulmonology]] | ||
Latest revision as of 17:04, 23 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]
Overview
There is no effective treatment for acute interstitial pneumonitis, Management in general includes supportive therapy and administration of glucocorticosteroids and Immunosuppressive agents.
Supportive care
- Patients with acute interstitial pneumonitis receive supportive care alongside the medical therapy[1]:
- Pulmonary rehabilitation (eg, patient education, optimal exercise program)
- Maintain ideal body-mass index
- Reduction of weight if obese
- Nutritional support if the patient is cachectic
- Vaccination against possible causes of pulmonary inflammation as influenza and pneumococcal vaccines.[2]
Medical Therapy
- Corticosteroid therapy:[3]
- Once the diagnosis of acute interstitial pneumonitis is confirmed, high doses of glucocorticosteroids (eg, methylprednisolone) should be administered.
- Monitor the patient for glucocorticosteroid-induced side effects (eg, hyperglycemia, increased susceptibility to infection, gastritis).
- Immunosuppressive therapy
References
- ↑ Suh GY, Kang EH, Chung MP, Lee KS, Han J, Kitaichi M, Kwon OJ (March 2006). "Early intervention can improve clinical outcome of acute interstitial pneumonia". Chest. 129 (3): 753–61. doi:10.1378/chest.129.3.753. PMID 16537878.
- ↑ Tomczyk S, Bennett NM, Stoecker C, Gierke R, Moore MR, Whitney CG, Hadler S, Pilishvili T (September 2014). "Use of 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine among adults aged ≥65 years: recommendations of the Advisory Committee on Immunization Practices (ACIP)". MMWR Morb. Mortal. Wkly. Rep. 63 (37): 822–5. PMC 5779453. PMID 25233284.
- ↑ Avnon LS, Pikovsky O, Sion-Vardy N, Almog Y (January 2009). "Acute interstitial pneumonia-Hamman-Rich syndrome: clinical characteristics and diagnostic and therapeutic considerations". Anesth. Analg. 108 (1): 232–7. doi:10.1213/ane.0b013e318188af7a. PMID 19095855.