Fibromuscular dysplasia natural history, complications and prognosis: Difference between revisions

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{{Fibromuscular dysplasia}}
{{Fibromuscular dysplasia}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}}{{M.B}}


==Overview==
== Overview ==
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Current knowledge about natural history, the efficacy of medical therapies, complications and prognosis of FMD, are really restricted; however the natural history of FMD is benign, and the long-term prognosis of patients with FMD is good, and its existence alone is not an indication for preventive intervention or surgery.


OR
[[Renal]] or cervival artery [[dissection]] and [[Intracranial]] [[aneurysms]] [[rupture]] and [[SAH]] are the most common complications of FMD.


Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
==Natural History, Complications, and Prognosis==
==Natural History, Complications, and Prognosis==


===Natural History===
===Natural History===
*The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.  
Current knowledge about natural history, the efficacy of medical therapies, complications and prognosis of FMD, are really restricted; however the natural history of FMD is benign.
*The symptoms of (disease name) typically develop ___ years after exposure to ___.
 
*If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
There are numerous top research priorities in determination of the natural history of FMD in the asymptomatic and symptomatic patient, progression, [[vascular]] events, [[complications]], and many unanswered aspects of FMD.


===Complications===
===Complications===
*Common complications of [disease name] include:
*Common complications of FMD include:
**[Complication 1]
**[[Renal]] or cervival artery [[dissection]]
**[Complication 2]
**[[Intracranial]] [[aneurysms]] [[rupture]] and [[SAH]]
**[Complication 3]
**[[Carotid-cavernous]] [[fistula]]
**[[Vertebral]] [[arteriovenous]] [[fistula]]
Cervical artery dissection is a classical complication of cervicocranial FMD
In the US FMD registry, about 20% of patients suffered from carotid arteries [[dissection]].<ref>{{Cite journal
| author = [[Jeffrey W. Olin]], [[James Froehlich]], [[Xiaokui Gu]], [[J. Michael Bacharach]], [[Kim Eagle]], [[Bruce H. Gray]], [[Michael R. Jaff]], [[Esther S. H. Kim]], [[Pam Mace]], [[Alan H. Matsumoto]], [[Robert D. McBane]], [[Eva Kline-Rogers]], [[Christopher J. White]] & [[Heather L. Gornik]]
| title = The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients
| journal = [[Circulation]]
| volume = 125
| issue = 25
| pages = 3182–3190
| year = 2012
| month = June
| doi = 10.1161/CIRCULATIONAHA.112.091223
| pmid = 22615343
}}</ref>


===Prognosis===
===Prognosis===
*Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
*The long-term prognosis of patients with the cervico-cranial FMD is good, and its existence alone is not an indication for preventive surgery.
*Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
*The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
*[Subtype of disease/malignancy] is associated with the most favorable prognosis.
*The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.


==References==
==References==

Latest revision as of 16:25, 1 August 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohsen Basiri M.D.

Overview

Current knowledge about natural history, the efficacy of medical therapies, complications and prognosis of FMD, are really restricted; however the natural history of FMD is benign, and the long-term prognosis of patients with FMD is good, and its existence alone is not an indication for preventive intervention or surgery.

Renal or cervival artery dissection and Intracranial aneurysms rupture and SAH are the most common complications of FMD.

Natural History, Complications, and Prognosis

Natural History

Current knowledge about natural history, the efficacy of medical therapies, complications and prognosis of FMD, are really restricted; however the natural history of FMD is benign.

There are numerous top research priorities in determination of the natural history of FMD in the asymptomatic and symptomatic patient, progression, vascular events, complications, and many unanswered aspects of FMD.

Complications

Cervical artery dissection is a classical complication of cervicocranial FMD In the US FMD registry, about 20% of patients suffered from carotid arteries dissection.[1]

Prognosis

  • The long-term prognosis of patients with the cervico-cranial FMD is good, and its existence alone is not an indication for preventive surgery.

References

  1. Jeffrey W. Olin, James Froehlich, Xiaokui Gu, J. Michael Bacharach, Kim Eagle, Bruce H. Gray, Michael R. Jaff, Esther S. H. Kim, Pam Mace, Alan H. Matsumoto, Robert D. McBane, Eva Kline-Rogers, Christopher J. White & Heather L. Gornik (2012). "The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients". Circulation. 125 (25): 3182–3190. doi:10.1161/CIRCULATIONAHA.112.091223. PMID 22615343. Unknown parameter |month= ignored (help)

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