Methemoglobinemia screening: Difference between revisions
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{{Methemoglobinemia}} | {{Methemoglobinemia}} | ||
{{CMG}} {{AE}} | {{CMG}}; {{AE}}{{AKS}} | ||
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==Overview== | ==Overview== | ||
[[Methemoglobinemia]] screening is not routinely done in the United States. | |||
==Screening== | ==Screening== | ||
Currently we have a screening test for G6PD deficiency. It is called methemoglobin reduction test (MRT), it is not expensive and it uses cord blood of neonates to check for the enzyme deficiency. Even though it has low sensitivity around 65%, it does have acceptable specificity | *Methemoglobinemia screening in the United States is not routinely done. | ||
*Newborn screening for G6PD is also not routinely done in the United States. It is performed only in neonates presenting with jaundice. <ref name="pmid10916676">{{cite journal| author=Mehta A, Mason PJ, Vulliamy TJ| title=Glucose-6-phosphate dehydrogenase deficiency. | journal=Baillieres Best Pract Res Clin Haematol | year= 2000 | volume= 13 | issue= 1 | pages= 21-38 | pmid=10916676 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10916676 }} </ref> | |||
*Currently we have a screening test for [[G6PD deficiency]] that has been tested in Thai population, since [[G6PD]] is very common in this patient population. It is called [[methemoglobin reduction test]] (MRT), it is not expensive and it uses cord blood of neonates to check for the [[enzyme deficiency]]. Even though it has low sensitivity around 65%, it does have acceptable specificity close to 90%. <ref name="pmid11529386">{{cite journal| author=Sanpavat S, Nuchprayoon I, Kittikalayawong A, Ungbumnet W| title=The value of methemoglobin reduction test as a screening test for neonatal glucose 6-phosphate dehydrogenase deficiency. | journal=J Med Assoc Thai | year= 2001 | volume= 84 Suppl 1 | issue= | pages= S91-8 | pmid=11529386 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11529386 }} </ref> | |||
==Referrences== | |||
{{ | {{Reflist|2}} | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
Latest revision as of 21:16, 31 July 2018
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Methemoglobinemia Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Methemoglobinemia screening On the Web |
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American Roentgen Ray Society Images of Methemoglobinemia screening |
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Risk calculators and risk factors for Methemoglobinemia screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aksiniya Stevasarova, M.D.
Overview
Methemoglobinemia screening is not routinely done in the United States.
Screening
- Methemoglobinemia screening in the United States is not routinely done.
- Newborn screening for G6PD is also not routinely done in the United States. It is performed only in neonates presenting with jaundice. [1]
- Currently we have a screening test for G6PD deficiency that has been tested in Thai population, since G6PD is very common in this patient population. It is called methemoglobin reduction test (MRT), it is not expensive and it uses cord blood of neonates to check for the enzyme deficiency. Even though it has low sensitivity around 65%, it does have acceptable specificity close to 90%. [2]
Referrences
- ↑ Mehta A, Mason PJ, Vulliamy TJ (2000). "Glucose-6-phosphate dehydrogenase deficiency". Baillieres Best Pract Res Clin Haematol. 13 (1): 21–38. PMID 10916676.
- ↑ Sanpavat S, Nuchprayoon I, Kittikalayawong A, Ungbumnet W (2001). "The value of methemoglobin reduction test as a screening test for neonatal glucose 6-phosphate dehydrogenase deficiency". J Med Assoc Thai. 84 Suppl 1: S91–8. PMID 11529386.