Cryoglobulinemia natural history, complications and prognosis: Difference between revisions

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==Complications==
==Complications==
The complications of cryoglobulinemia are as follows:
The complications of cryoglobulinemia are as follows:
*Rapidly progressive neuropathy
*Rapidly progressive [[neuropathy]]
* Heart failure
* [[Congestive heart failure|Heart failure]]
* Digital ischemia threatening amputation
* Digital [[ischemia]] threatening amputation
* Diffuse alveolar hemorrhage resulting in hemoptysis
* Diffuse [[Alveolus|alveolar]] [[Bleeding|hemorrhage]] resulting in [[hemoptysis]]
* Respiratory failure
* [[Respiratory failure]]
* Stroke
* [[Stroke]]
* End stage renal disease
* [[Chronic renal failure|End stage renal disease]]


==Prognosis==
==Prognosis==
Patients having severe manifestations of the disease such as pulmonary vasculitis, end-stage renal disease, cardiac vasculitis and central nervous system vascultitis have generally poor prognosis of the disease. The prognosis of cryoglobulinemia depends on the organ system involved and varies accordingly.
Patients having severe manifestations of the disease such as pulmonary vasculitis, end-stage renal disease, cardiac vasculitis and central nervous system vasculitis have generally poor prognosis of the disease. The prognosis of cryoglobulinemia depends on the organ system involved and varies accordingly.


{| class="wikitable"
{| class="wikitable"
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!Survival rate
!Survival rate
|-
|-
|Glomerulonephritis
|[[Glomerular disease|Glomerulonephritis]]
|79%
|79%
|-
|-
|Pulmonary vasculitis
|Pulmonary [[vasculitis]]
|22%
|22%
|-
|-
|Central nervous system vasculitis
|Central nervous system [[vasculitis]]
|66%
|66%
|-
|-

Latest revision as of 23:29, 30 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Feham Tariq, MD [2]

Overview

Natural History

Complications

The complications of cryoglobulinemia are as follows:

Prognosis

Patients having severe manifestations of the disease such as pulmonary vasculitis, end-stage renal disease, cardiac vasculitis and central nervous system vasculitis have generally poor prognosis of the disease. The prognosis of cryoglobulinemia depends on the organ system involved and varies accordingly.

Organ system involved Survival rate
Glomerulonephritis 79%
Pulmonary vasculitis 22%
Central nervous system vasculitis 66%
Gastrointestinal vasculitis 67%
Cardiac vasculitis 100%

References


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