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{{Minimal change disease}}
{{CMG}}; {{AE}} {{VKG}}
== Overview ==
== Overview ==
The cause of minimal change disease has not been identified or idiopathic.Nephrotic syndrome is most commonly as a result of damage to the clusters of tiny blood vessels (glomeruli) .But secondary causes may be due to Drugs,Toxins,Infection and Tumor .
The cause of [[minimal change disease]] has not been identified or [[idiopathic]]. [[Nephrotic syndrome]] is most commonly as a result of damage to the clusters of tiny blood vessels (glomeruli).But secondary causes may be due to Drugs, Toxins, [[Infection]], and [[Tumor]].


=== Common Causes ===
== Common Causes ==
Common risk factors in the development of minimal change disease include:<ref name="IijimaHamahira2002">{{cite journal|last1=Iijima|first1=Kazumoto|last2=Hamahira|first2=Kiyoshi|last3=Tanaka|first3=Ryojiro|last4=Kobayashi|first4=Akiko|last5=Nozu|first5=Kandai|last6=Nakamura|first6=Hajime|last7=Yoshikawa|first7=Norishige|title=Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome|journal=Kidney International|volume=61|issue=5|year=2002|pages=1801–1805|issn=00852538|doi=10.1046/j.1523-1755.2002.00303.x}}</ref>
Common [[Risk factor|risk factors]] in the development of [[minimal change disease]] include:<ref name="IijimaHamahira2002">{{cite journal|last1=Iijima|first1=Kazumoto|last2=Hamahira|first2=Kiyoshi|last3=Tanaka|first3=Ryojiro|last4=Kobayashi|first4=Akiko|last5=Nozu|first5=Kandai|last6=Nakamura|first6=Hajime|last7=Yoshikawa|first7=Norishige|title=Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome|journal=Kidney International|volume=61|issue=5|year=2002|pages=1801–1805|issn=00852538|doi=10.1046/j.1523-1755.2002.00303.x}}</ref>
*Children within the Age >1 year but <8 years
 
*[[Null|Hodgkin lymphoma]]
=== Common Risk Factors ===
*[[Null|leukemia]]
*Children within the Age >1 year and <8 years
*[[Null|Recent viral illness]]
*[[Hodgkin's lymphoma|Hodgkin lymphoma]]
*Toxins like  Mercury, bee stings, fire coral exposure are one of the causes for minimal change disease.
*[[leukemia]]
*Drugs like<ref name="pmid279404603">{{cite journal |vauthors=Vivarelli M, Massella L, Ruggiero B, Emma F |title=Minimal Change Disease |journal=Clin J Am Soc Nephrol |volume=12 |issue=2 |pages=332–345 |date=February 2017 |pmid=27940460 |pmc=5293332 |doi=10.2215/CJN.05000516 |url=}}</ref>  
*Recent [[viral]] illness
*Toxins such as [[Mercury]], [[bee]] stings, fire coral exposure are one of the causes for minimal change disease.
*[[Medication|Medications]] such as:<ref name="pmid279404603">{{cite journal |vauthors=Vivarelli M, Massella L, Ruggiero B, Emma F |title=Minimal Change Disease |journal=Clin J Am Soc Nephrol |volume=12 |issue=2 |pages=332–345 |date=February 2017 |pmid=27940460 |pmc=5293332 |doi=10.2215/CJN.05000516 |url=}}</ref>  
**Salazopyrin   
**Salazopyrin   
**Mercury   
**[[Mercury]]  
**Tiopronin   
**[[Tiopronin]]  
**Lithium   
**[[Lithium]]  
**D-penicillamine   
**[[D-penicillamine]]  
**Gold  
**[[Gold]]
**Tyrosine-kinase inhibitor  
**[[Tyrosine kinase inhibitor|Tyrosine-kinase inhibitor]]


=== Less Common Causes ===
=== Less Common Causes ===
Less common causes of  minimal change disease include:<ref name="pmid279404602">{{cite journal |vauthors=Vivarelli M, Massella L, Ruggiero B, Emma F |title=Minimal Change Disease |journal=Clin J Am Soc Nephrol |volume=12 |issue=2 |pages=332–345 |date=February 2017 |pmid=27940460 |pmc=5293332 |doi=10.2215/CJN.05000516 |url=}}</ref>
Less common causes of minimal change disease include:<ref name="pmid279404602">{{cite journal |vauthors=Vivarelli M, Massella L, Ruggiero B, Emma F |title=Minimal Change Disease |journal=Clin J Am Soc Nephrol |volume=12 |issue=2 |pages=332–345 |date=February 2017 |pmid=27940460 |pmc=5293332 |doi=10.2215/CJN.05000516 |url=}}</ref><ref name="VivarelliMassella20172">{{cite journal|last1=Vivarelli|first1=Marina|last2=Massella|first2=Laura|last3=Ruggiero|first3=Barbara|last4=Emma|first4=Francesco|title=Minimal Change Disease|journal=Clinical Journal of the American Society of Nephrology|volume=12|issue=2|year=2017|pages=332–345|issn=1555-9041|doi=10.2215/CJN.05000516}}</ref>
* Hepatitis B or C infection
* [[Hepatitis B]] or [[Hepatitis C|HCV]] infection
* low birth weight (LBW)
* L[[Low birth weight|ow birth weigh]]<nowiki/>t (LBW)
* Hematopoietic stem cell transplantation
* [[Hematopoietic]] stem cell transplantation
{{Minimal change disease}}
{{Minimal change disease}}



Latest revision as of 14:21, 13 June 2018

Minimal Change Disease Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Minimal Change Disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Immunohistology

Electron Microscopy

Electrocardiogram

X-ray

Echocardiorgaphy or Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Minimal change disease risk factors On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Minimal change disease risk factors

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Minimal change disease risk factors

CDC on Minimal change disease risk factors

Minimal change disease risk factors in the news

Blogs on Minimal change disease risk factors

Directions to Hospitals Treating Minimal change disease

Risk calculators and risk factors for Minimal change disease risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

The cause of minimal change disease has not been identified or idiopathic. Nephrotic syndrome is most commonly as a result of damage to the clusters of tiny blood vessels (glomeruli).But secondary causes may be due to Drugs, Toxins, Infection, and Tumor.

Common Causes

Common risk factors in the development of minimal change disease include:[1]

Common Risk Factors

Less Common Causes

Less common causes of minimal change disease include:[3][4]

Minimal Change Disease Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Minimal Change Disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Immunohistology

Electron Microscopy

Electrocardiogram

X-ray

Echocardiorgaphy or Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Minimal change disease risk factors On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Minimal change disease risk factors

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Minimal change disease risk factors

CDC on Minimal change disease risk factors

Minimal change disease risk factors in the news

Blogs on Minimal change disease risk factors

Directions to Hospitals Treating Minimal change disease

Risk calculators and risk factors for Minimal change disease risk factors

References

  1. Iijima, Kazumoto; Hamahira, Kiyoshi; Tanaka, Ryojiro; Kobayashi, Akiko; Nozu, Kandai; Nakamura, Hajime; Yoshikawa, Norishige (2002). "Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome". Kidney International. 61 (5): 1801–1805. doi:10.1046/j.1523-1755.2002.00303.x. ISSN 0085-2538.
  2. Vivarelli M, Massella L, Ruggiero B, Emma F (February 2017). "Minimal Change Disease". Clin J Am Soc Nephrol. 12 (2): 332–345. doi:10.2215/CJN.05000516. PMC 5293332. PMID 27940460.
  3. Vivarelli M, Massella L, Ruggiero B, Emma F (February 2017). "Minimal Change Disease". Clin J Am Soc Nephrol. 12 (2): 332–345. doi:10.2215/CJN.05000516. PMC 5293332. PMID 27940460.
  4. Vivarelli, Marina; Massella, Laura; Ruggiero, Barbara; Emma, Francesco (2017). "Minimal Change Disease". Clinical Journal of the American Society of Nephrology. 12 (2): 332–345. doi:10.2215/CJN.05000516. ISSN 1555-9041.

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