Fibromuscular dysplasia natural history, complications and prognosis: Difference between revisions
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== Overview == | |||
Current knowledge about natural history, the efficacy of medical therapies, complications and prognosis of FMD, are really restricted; however the natural history of FMD is benign, and the long-term prognosis of patients with FMD is good, and its existence alone is not an indication for preventive intervention or surgery. | |||
[[Renal]] or cervival artery [[dissection]] and [[Intracranial]] [[aneurysms]] [[rupture]] and [[SAH]] are the most common complications of FMD. | |||
==Natural History, Complications, and Prognosis== | ==Natural History, Complications, and Prognosis== | ||
===Natural History=== | ===Natural History=== | ||
Current knowledge about natural history, the efficacy of medical therapies, complications and prognosis of FMD, are really restricted; however the natural history of FMD is benign. | |||
There are numerous top research priorities in determination of the natural history of FMD in the asymptomatic and symptomatic patient, progression, [[vascular]] events, [[complications]], and many unanswered aspects of FMD. | |||
===Complications=== | ===Complications=== | ||
*Common complications of | *Common complications of FMD include: | ||
**[ | **[[Renal]] or cervival artery [[dissection]] | ||
**[ | **[[Intracranial]] [[aneurysms]] [[rupture]] and [[SAH]] | ||
**[ | **[[Carotid-cavernous]] [[fistula]] | ||
**[[Vertebral]] [[arteriovenous]] [[fistula]] | |||
Cervical artery dissection is a classical complication of cervicocranial FMD | |||
In the US FMD registry, about 20% of patients suffered from carotid arteries [[dissection]].<ref>{{Cite journal | |||
| author = [[Jeffrey W. Olin]], [[James Froehlich]], [[Xiaokui Gu]], [[J. Michael Bacharach]], [[Kim Eagle]], [[Bruce H. Gray]], [[Michael R. Jaff]], [[Esther S. H. Kim]], [[Pam Mace]], [[Alan H. Matsumoto]], [[Robert D. McBane]], [[Eva Kline-Rogers]], [[Christopher J. White]] & [[Heather L. Gornik]] | |||
| title = The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients | |||
| journal = [[Circulation]] | |||
| volume = 125 | |||
| issue = 25 | |||
| pages = 3182–3190 | |||
| year = 2012 | |||
| month = June | |||
| doi = 10.1161/CIRCULATIONAHA.112.091223 | |||
| pmid = 22615343 | |||
}}</ref> | |||
===Prognosis=== | ===Prognosis=== | ||
* | *The long-term prognosis of patients with the cervico-cranial FMD is good, and its existence alone is not an indication for preventive surgery. | ||
==References== | ==References== |
Latest revision as of 16:25, 1 August 2018
Fibromuscular dysplasia Microchapters |
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ASA/ACCF/AHA Guideline Recommendations |
Management of Patients With Fibromuscular Dysplasia of the Extracranial Carotid Arteries |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohsen Basiri M.D.
Overview
Current knowledge about natural history, the efficacy of medical therapies, complications and prognosis of FMD, are really restricted; however the natural history of FMD is benign, and the long-term prognosis of patients with FMD is good, and its existence alone is not an indication for preventive intervention or surgery.
Renal or cervival artery dissection and Intracranial aneurysms rupture and SAH are the most common complications of FMD.
Natural History, Complications, and Prognosis
Natural History
Current knowledge about natural history, the efficacy of medical therapies, complications and prognosis of FMD, are really restricted; however the natural history of FMD is benign.
There are numerous top research priorities in determination of the natural history of FMD in the asymptomatic and symptomatic patient, progression, vascular events, complications, and many unanswered aspects of FMD.
Complications
- Common complications of FMD include:
- Renal or cervival artery dissection
- Intracranial aneurysms rupture and SAH
- Carotid-cavernous fistula
- Vertebral arteriovenous fistula
Cervical artery dissection is a classical complication of cervicocranial FMD In the US FMD registry, about 20% of patients suffered from carotid arteries dissection.[1]
Prognosis
- The long-term prognosis of patients with the cervico-cranial FMD is good, and its existence alone is not an indication for preventive surgery.
References
- ↑ Jeffrey W. Olin, James Froehlich, Xiaokui Gu, J. Michael Bacharach, Kim Eagle, Bruce H. Gray, Michael R. Jaff, Esther S. H. Kim, Pam Mace, Alan H. Matsumoto, Robert D. McBane, Eva Kline-Rogers, Christopher J. White & Heather L. Gornik (2012). "The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients". Circulation. 125 (25): 3182–3190. doi:10.1161/CIRCULATIONAHA.112.091223. PMID 22615343. Unknown parameter
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