Fibromuscular dysplasia causes: Difference between revisions

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{{CMG}}; {{AE}} {{M.B}}
{{CMG}}; {{AE}} {{M.B}}
==Overview==
==Overview==
The cause of fibromuscular dysplasia has not been identified. To review risk factors for the development of FMD, click [[Pericarditis causes#Overview|here]].
The cause of fibromuscular dysplasia has not been identified.


== Cause ==
The cause of fibromuscular dysplasia has not been identified. A variety of factors have been implicated. These include:


*[Disease name] is caused by an infection with [pathogen name].
* [[Genetics|Genetic]] predisposition with a reported autosomal mode of [[inheritance]] in some families<ref>Perdu J, Boutouyrie P, Bourgain C, et al. Inheritance of arterial lesions in
*[Pathogen name] is caused by [pathogen name].
renal 􀉹bromuscular dysplasia. J Hum Hypertens 2007; 21:393</ref><ref>Ganesh SK, Morissette R, Xu Z, et al. Clinical and biochemical pro􀉹les
 
suggest 􀉹bromuscular dysplasia is a systemic disease with altered TGF-β
===Less Common Causes===
expression and connective tissue features. FASEB J 2014; 28:3313</ref>
Less common causes of [[disease name]] include:
* Hormonal influence, given the predominance in women of childbearing age
*[Cause1]
* Mechanical factors such as stretching of smooth muscle cells and [[trauma]] to the blood vessel wall
*[Cause2]
* [[Ischemia]] of the blood vessel wall due to fibrotic occlusion of the vasavasorum
*[Cause3]
 
===Genetic Causes===
*[Disease name] is caused by a mutation in the [gene name] gene.
 
===Causes by Organ System===
 
{| style="width:80%; height:100px" border="1"
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular'''
| style="width:75%" bgcolor="Beige" ; border="1" | No underlying causes
|-
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Dental'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Dermatologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Endocrine'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Environmental'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Genetic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Hematologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Neurologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Oncologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Psychiatric'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Pulmonary'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Sexual'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Trauma'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Urologic'''
| bgcolor="Beige" | No underlying causes
|-
|- bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| bgcolor="Beige" | No underlying causes
|-
|}
 
===Causes in Alphabetical Order===
List the causes of the disease in alphabetical order.
{{columns-list|3|
* Cause 1
* Cause 2
* Cause 3
* Cause 4
* Cause 5
* Cause 6
* Cause 7
* Cause 8
* Cause 9
* Cause 10
}}


==References==
==References==

Latest revision as of 22:23, 19 August 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohsen Basiri M.D.

Overview

The cause of fibromuscular dysplasia has not been identified.

Cause

The cause of fibromuscular dysplasia has not been identified. A variety of factors have been implicated. These include:

  • Genetic predisposition with a reported autosomal mode of inheritance in some families[1][2]
  • Hormonal influence, given the predominance in women of childbearing age
  • Mechanical factors such as stretching of smooth muscle cells and trauma to the blood vessel wall
  • Ischemia of the blood vessel wall due to fibrotic occlusion of the vasavasorum

References

  1. ↑ Perdu J, Boutouyrie P, Bourgain C, et al. Inheritance of arterial lesions in renal 􀉹bromuscular dysplasia. J Hum Hypertens 2007; 21:393
  2. ↑ Ganesh SK, Morissette R, Xu Z, et al. Clinical and biochemical pro􀉹les suggest 􀉹bromuscular dysplasia is a systemic disease with altered TGF-β expression and connective tissue features. FASEB J 2014; 28:3313

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