Paroxysmal nocturnal hemoglobinuria other diagnostic studies: Difference between revisions
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{{Paroxysmal nocturnal hemoglobinuria}} | {{Paroxysmal nocturnal hemoglobinuria}} | ||
{{CMG}}; {{AE}} | {{CMG}} {{shyam}}; {{AE}} | ||
==Overview== | ==Overview== | ||
There are no other diagnostic studies associated with | Fluorescent aerolysin (FLAER) can be used to diagnose There are no other diagnostic studies associated with paroxysmal nocturnal hemoglobinuria. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
Fluorescent aerolysin (FLAER) can be used to diagnose paroxysmal nocturnal hemoglobinuria.<ref name="pmid18063459">{{cite journal| author=Brodsky RA| title=Advances in the diagnosis and therapy of paroxysmal nocturnal hemoglobinuria. | journal=Blood Rev | year= 2008 | volume= 22 | issue= 2 | pages= 65-74 | pmid=18063459 | doi=10.1016/j.blre.2007.10.002 | pmc=2290854 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18063459 }} </ref> This test is based on the idea that FLAER binds to GPI anchors. In the absence of GPI anchors on the cell membrane, FLAER will not bind, so PNH cells are negative for FLAER. | |||
==References== | ==References== | ||
Latest revision as of 22:28, 18 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief:
Overview
Fluorescent aerolysin (FLAER) can be used to diagnose There are no other diagnostic studies associated with paroxysmal nocturnal hemoglobinuria.
Other Diagnostic Studies
Fluorescent aerolysin (FLAER) can be used to diagnose paroxysmal nocturnal hemoglobinuria.[1] This test is based on the idea that FLAER binds to GPI anchors. In the absence of GPI anchors on the cell membrane, FLAER will not bind, so PNH cells are negative for FLAER.
References
- ↑ Brodsky RA (2008). "Advances in the diagnosis and therapy of paroxysmal nocturnal hemoglobinuria". Blood Rev. 22 (2): 65–74. doi:10.1016/j.blre.2007.10.002. PMC 2290854. PMID 18063459.