Paroxysmal nocturnal hemoglobinuria screening: Difference between revisions
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{{Paroxysmal nocturnal hemoglobinuria}} | {{Paroxysmal nocturnal hemoglobinuria}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{AEL}} | ||
==Overview== | ==Overview== | ||
According to the American society of hematology, screening for paroxysmal nocturnal hemolglobinuria is recommended among patients with [[hemoglobinuria]], cytopenia, suspected myelodysplasia, negative direct coombs test intravascular hemolytic anemia, refractory anemia, and aplastic anemia with no apparent sign of intravascular hemolysis. | |||
==Screening== | ==Screening== | ||
* According to the American society of hematology, screening for paroxysmal nocturnal hemolglobinuria is recommended among patients with:<ref name="pmid16051736">{{cite journal| author=Parker C, Omine M, Richards S, Nishimura J, Bessler M, Ware R et al.| title=Diagnosis and management of paroxysmal nocturnal hemoglobinuria. | journal=Blood | year= 2005 | volume= 106 | issue= 12 | pages= 3699-709 | pmid=16051736 | doi=10.1182/blood-2005-04-1717 | pmc=1895106 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16051736 }}</ref> | |||
** Hemoglobinuria | |||
** Cytopenia | |||
** Suspected Myelodysplasia | |||
According to the | ** Negative direct coombs test intravascular hemolytic anemia | ||
** Refractory anemia | |||
** Aplastic anemia with no apparent sign of intravascular hemolysis | |||
** Unexplained thrombosis especially in unusual sites as: | |||
*** Budd-Chiari syndrome | |||
* | *** Other intra-abdominal sites (eg, mesenteric or portal veins) | ||
* | *** Cerebral veins | ||
* | *** Dermal veins | ||
==References== | ==References== | ||
Latest revision as of 23:27, 31 October 2018
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Paroxysmal nocturnal hemoglobinuria Microchapters |
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Differentiating Paroxysmal nocturnal hemoglobinuria from other Diseases |
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Paroxysmal nocturnal hemoglobinuria screening On the Web |
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Risk calculators and risk factors for Paroxysmal nocturnal hemoglobinuria screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
According to the American society of hematology, screening for paroxysmal nocturnal hemolglobinuria is recommended among patients with hemoglobinuria, cytopenia, suspected myelodysplasia, negative direct coombs test intravascular hemolytic anemia, refractory anemia, and aplastic anemia with no apparent sign of intravascular hemolysis.
Screening
- According to the American society of hematology, screening for paroxysmal nocturnal hemolglobinuria is recommended among patients with:[1]
- Hemoglobinuria
- Cytopenia
- Suspected Myelodysplasia
- Negative direct coombs test intravascular hemolytic anemia
- Refractory anemia
- Aplastic anemia with no apparent sign of intravascular hemolysis
- Unexplained thrombosis especially in unusual sites as:
- Budd-Chiari syndrome
- Other intra-abdominal sites (eg, mesenteric or portal veins)
- Cerebral veins
- Dermal veins
References
- ↑ Parker C, Omine M, Richards S, Nishimura J, Bessler M, Ware R; et al. (2005). "Diagnosis and management of paroxysmal nocturnal hemoglobinuria". Blood. 106 (12): 3699–709. doi:10.1182/blood-2005-04-1717. PMC 1895106. PMID 16051736.