Paroxysmal nocturnal hemoglobinuria classification: Difference between revisions
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==Classification== | ==Classification== | ||
Paroxysmal nocturnal hemoglobinuria may be classified according to diagnosis results into three subtypes:<ref name="pmid1895106">{{cite journal| author=Mok WM, Herschkowitz S, Krieger NR| title=In vivo studies identify 5 alpha-pregnan-3 alpha-ol-20-one as an active anesthetic agent. | journal=J Neurochem | year= 1991 | volume= 57 | issue= 4 | pages= 1296-301 | pmid=1895106 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1895106 }}</ref> | Paroxysmal nocturnal hemoglobinuria may be classified according to diagnosis results into three subtypes:<ref name="pmid1895106">{{cite journal| author=Mok WM, Herschkowitz S, Krieger NR| title=In vivo studies identify 5 alpha-pregnan-3 alpha-ol-20-one as an active anesthetic agent. | journal=J Neurochem | year= 1991 | volume= 57 | issue= 4 | pages= 1296-301 | pmid=1895106 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1895106 }}</ref><ref name="pmid16051736">{{cite journal| author=Parker C, Omine M, Richards S, Nishimura J, Bessler M, Ware R et al.| title=Diagnosis and management of paroxysmal nocturnal hemoglobinuria. | journal=Blood | year= 2005 | volume= 106 | issue= 12 | pages= 3699-709 | pmid=16051736 | doi=10.1182/blood-2005-04-1717 | pmc=1895106 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16051736 }}</ref> | ||
* Classic PNH: Other bone marrow disorders with a confirmed diagnosis of PNH. | * Classic PNH: Other [[bone marrow]] disorders with a confirmed diagnosis of PNH. | ||
* Secondary PNH: When PNH is due to other bone marrow disorder as aplastic anemia or myelodysplastic syndrome. | * Secondary PNH: When PNH is due to other bone marrow disorder as [[aplastic anemia]] or [[myelodysplastic syndrome]]. | ||
* Subclinical PNH: No signs or symptoms of PNH, however, flow cytometry shows results of PNH. | * Subclinical PNH: No signs or symptoms of PNH, however, [[flow cytometry]] shows results of PNH. | ||
==References== | ==References== | ||
Latest revision as of 23:02, 31 October 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Paroxysmal nocturnal hemoglobinuria may be classified according to the diagnosis results into three subtypes. The subtypes of PNH include classic PNH, secondary PNH, or subclinical PNH.
Classification
Paroxysmal nocturnal hemoglobinuria may be classified according to diagnosis results into three subtypes:[1][2]
- Classic PNH: Other bone marrow disorders with a confirmed diagnosis of PNH.
- Secondary PNH: When PNH is due to other bone marrow disorder as aplastic anemia or myelodysplastic syndrome.
- Subclinical PNH: No signs or symptoms of PNH, however, flow cytometry shows results of PNH.
References
- ↑ Mok WM, Herschkowitz S, Krieger NR (1991). "In vivo studies identify 5 alpha-pregnan-3 alpha-ol-20-one as an active anesthetic agent". J Neurochem. 57 (4): 1296–301. PMID 1895106 Check
|pmid=value (help). - ↑ Parker C, Omine M, Richards S, Nishimura J, Bessler M, Ware R; et al. (2005). "Diagnosis and management of paroxysmal nocturnal hemoglobinuria". Blood. 106 (12): 3699–709. doi:10.1182/blood-2005-04-1717. PMC 1895106. PMID 16051736.