Kaposi's sarcoma laboratory findings: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{CMG}} {{AE}} {{HL}}{{ADS}} | |||
{{CMG}} {{AE}} {{HL}} | |||
{{Kaposi's sarcoma}} | {{Kaposi's sarcoma}} | ||
==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of Kaposi's sarcoma include decreased [[hemoglobin]] level, positive [[HIV]] tests, and positive [[HHV-8]] [[antigen]] on immunohistochemistry. | Laboratory findings consistent with the diagnosis of Kaposi's sarcoma include decreased [[hemoglobin]] level, positive [[HIV]] tests, and positive [[HHV-8]] [[antigen]] on immunohistochemistry. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory findings consistent with the diagnosis of kaposi's sarcoma include: | Laboratory findings consistent with the diagnosis of kaposi's sarcoma include:<ref name="cancer">Sarcoma- Kaposi Guide. Cancer.Net (2015) http://www.cancer.net/cancer-types/sarcoma-kaposi/risk-factors-and-prevention Accessed on January, 20 2015</ref> | ||
====Complete blood count==== | ====Complete blood count==== | ||
* Decreased [[hemoglobin]] level | * Decreased [[hemoglobin]] level | ||
====Electrophoresis==== | ====Electrophoresis==== | ||
* Detect [[antibodies]] against KSHV | * Detect [[antibodies]] against Kaposi sarcoma herpes virus (KSHV) (also known as HHV-8) | ||
====ELISA==== | ====ELISA==== | ||
* Screens for [[HIV]] infection among Kaposi's sarcoma patients | * Screens for [[HIV]] infection among Kaposi's sarcoma patients | ||
| Line 17: | Line 16: | ||
* Confirms HIV infection among Kaposi's sarcoma patients | * Confirms HIV infection among Kaposi's sarcoma patients | ||
====Immunohistochemistry==== | ====Immunohistochemistry==== | ||
* Kaposi's sarcoma cells are typically CD34, [[HHV-8]], and D2-40 positive | * Kaposi's sarcoma cells are typically CD34, [[HHV-8]], LANA-1, and D2-40 positive. CD31 and CD34 testing may be useful to assess for vascular origin. | ||
==References== | ==References== | ||
Latest revision as of 14:25, 27 March 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]Amandeep Singh M.D.[3]
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Kaposi's sarcoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Kaposi's sarcoma laboratory findings On the Web |
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American Roentgen Ray Society Images of Kaposi's sarcoma laboratory findings |
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Risk calculators and risk factors for Kaposi's sarcoma laboratory findings |
Overview
Laboratory findings consistent with the diagnosis of Kaposi's sarcoma include decreased hemoglobin level, positive HIV tests, and positive HHV-8 antigen on immunohistochemistry.
Laboratory Findings
Laboratory findings consistent with the diagnosis of kaposi's sarcoma include:[1]
Complete blood count
- Decreased hemoglobin level
Electrophoresis
- Detect antibodies against Kaposi sarcoma herpes virus (KSHV) (also known as HHV-8)
ELISA
- Screens for HIV infection among Kaposi's sarcoma patients
Western Blot
- Confirms HIV infection among Kaposi's sarcoma patients
Immunohistochemistry
- Kaposi's sarcoma cells are typically CD34, HHV-8, LANA-1, and D2-40 positive. CD31 and CD34 testing may be useful to assess for vascular origin.
References
- ↑ Sarcoma- Kaposi Guide. Cancer.Net (2015) http://www.cancer.net/cancer-types/sarcoma-kaposi/risk-factors-and-prevention Accessed on January, 20 2015