Differential diagnosis project

Differential diagnosis project
Introduction
Guide
Template
Topics
Alphabetic Order

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Differential diagnosis is the process of distinguishing a particular disease or condition from others that present with similar clinical features.

A differential diagnostic procedure is generally a systematic diagnostic method used in each individual patient based on their specific condition to identify the presence of a disease entity where multiple alternatives are possible. This method is essentially a process of elimination or at least a process of obtaining information that shrinks the "probabilities" of candidate conditions to negligible levels, by using evidence such as symptoms, patient history, and medical knowledge.

The Differential Diagnosis Project aims to integrate the current body of medical literature in the new era of differential diagnosis into conjoined, systematic pages where the availability of comparing between different possibilities be possible for diagnostician, in conformity with practice guidelines, consensus statements, systematic reviews, and expert opinions.

Educational content provided herein is not intended to supplant but supplement clinical judgment. In light of the variability in epidemiological contexts and resources available to diagnose a disease, adjustment in diagnostic approach may be required to optimize patient care.

Disclaimer

All information is provided for educational purposes only. The content provided herein is not intended to supplant but supplement clinical judgment.

A

Abdominal pain

• Abdominal pain

• Abdominal pain and fever

• Abdominal pain, nausea and vomiting

• Abdominal pain and jaundice

• Abdominal pain and weight loss

• Abdominal pain and constipation

• Abdominal pain and diarrhea

• Abdominal pain and GI bleeding

• Abdominal pain, fever, and jaundice

• Abdominal pain, fever, nausea and vomiting

• Abdominal pain, fever, and diarrhea

• Abdominal pain, fever and constipation

• Abdominal pain, fever and weight loss

• Abdominal pain, fever and GI bleeding

• Abdominal pain, nausea,vomiting and jaundice

• Abdominal pain, nausea,vomiting and weight loss

• Abdominal pain, nausea,vomiting and constipation

• Abdominal pain, nausea,vomiting and diarrhea

• Abdominal pain, nausea, vomiting and GI bleeding

• Abdominal pain, jaundice and weight loss

• Abdominal pain, jaundice and diarrhea

• Abdominal pain, jaundice and GI bleeding

• Abdominal pain,weight loss and constipation

• Abdominal pain,weight loss and diarrhea

• Abdominal pain, weight loss and GI bleeding

• Abdominal pain, constipation and diarrhea

• Abdominal pain, constipation and GI bleeding

• Abdominal pain, diarrhea and GI bleeding

Abnormalities in micturition

• Abnormalities in micturition

Abscess

• Abscess

Acidosis

• Metabolic acidosis

• High anion gap metabolic acidosis

• High osmolar gap metabolic acidosis

• Metabolic acidosis and lactic acidosis

• Respiratory acidosis

Alkalosis

• Metabolic alkalosis

• Respiratory alkalosis

Anemia

• Anemia

• Microcytic anemia

• Normocytic anemia

• Macrocytic anemia

• Hypochromic anemia

• Normochromic anemia

• Anisochromic anemia

• Hemolytic anemia

• Anemia with intrinsic hemolysis

• Anemia with extrinsic hemolysis

• Anemia with low reticulocytosis

• Anemia with normal reticulocytosis

• Anemia with high reticulocytosis

Ankylosing spondylitis

• Ankylosing spondylitis

Arthritis

Polyarthritis

• Polyarthritis

• Polyarthritis with joint swelling

• Polyarthritis with fever

• Polyarthritis with weight loss

• Polyarthritis with claudication

• Polyarthritis with morning stiffness

• Polyarthritis with local erythema

• Polyarthritis with joint swelling and fever

• Polyarthritis with joint swelling, fever, and weight loss

Monoarthritis

• Monoarthritis

• Monoarthritis with joint swelling

• Monoarthritis with fever

• Monoarthritis with weight loss

• Monoarthritis with claudication

• Monoarthritis with morning stiffness

• Monoarthritis with local erythema

• Monoarthritis with joint swelling and fever

• Monoarthritis with joint swelling, fever, and weight loss

Ascites

• Ascites

B

Back pain

• Back pain

• Back pain and bowel or bladder dysfunction

• Back pain, bowel or bladder dysfunction and horner's syndrome

• Back pain and fever

• Back pain, fever and stiffness

• Back pain and heart murmur

• Back pain and headache

• Back pain and horner's syndrome

• Back pain and motor weakness

• Back pain, motor weakness and sensory deficit

• Back pain and nausea and vomiting

• Back pain and pulse deficit

• Back pain and sensory deficit

• Back pain and stiffness

• Back pain and syncopy

• Back pain and weight loss

• Back pain exhibiting "red flags"

Bleeding diathesis

• Bleeding diathesis

Bronchitis

• Bronchitis

• Fever, cough, dyspnea, and wheezing

C

Chest pain

• Chest pain

• Chest pain and cough

• Chest pain and fever

• Chest pain and dyspnea

• Chest pain and weight loss

• Chest pain, cough, and fever

• Chest pain, cough, and dyspnea

• Chest pain, cough, and weight loss

• Chest pain, fever, and dyspnea

• Chest pain, fever, and weight loss

• Chest pain, dyspnea, and weight loss

Cholestasis

• Cholestasis

Chronic watery diarrhea

• Chronic watery diarrhea

Coagulopathy

• Coagulopathy

Constipation

• Constipation

• Constipation and abdominal pain

• Constipation and anal pain

• Constipation and rectal bleeding

• Constipation and weight loss

• Constipation and tremor

Cough

• Productive cough

• Acute cough

• Chronic cough

• Cough and hemoptysis

• Cough and weight loss

• Cough and fever

• Cough and wheeze

• Cough, fever, and hemoptysis

• Cough, fever, and weight loss

• Cough, hemoptysis, and weight loss

Cyanosis

Central Cyanosis

• Central cyanosis

• Central cyanosis and dyspnea

• Central cyanosis and fever

• Central cyanosis and chest pain

• Central cyanosis and clubbing

• Central cyanosis, dyspnea, and fever

• Central cyanosis, dyspnea, and chest pain

• Central cyanosis, dyspnea, and clubbing

• Central cyanosis, fever, and chest pain

• Central cyanosis, fever, and clubbing

• Central cyanosis, chest pain, and clubbing

• Central cyanosis, dyspnea, fever, and chest pain

• Central cyanosis, fever, chest pain, and clubbing

• Central cyanosis, dyspnea, fever, and clubbing

• Central cyanosis, dyspnea, fever, chest pain, and clubbing

Peripheral Cyanosis

• Peripheral cyanosis

• Peripheral cyanosis and dyspnea

• Peripheral cyanosis and fever

• Peripheral cyanosis and chest pain

• Peripheral cyanosis and clubbing

• Peripheral cyanosis, dyspnea, and fever

• Peripheral cyanosis, dyspnea, and chest pain

• Peripheral cyanosis, dyspnea, and clubbing

• Peripheral cyanosis, fever, and chest pain

• Peripheral cyanosis, fever, and clubbing

• Peripheral cyanosis, chest pain, and clubbing

• Peripheral cyanosis, dyspnea, fever, and chest pain

• Peripheral cyanosis, fever, chest pain, and clubbing

• Peripheral cyanosis, dyspnea, fever, and clubbing

• Peripheral cyanosis, dyspnea, fever, chest pain, and clubbing

D

Diabetes insipidus

• Diabetes insipidus

Diarrhea

• Diarrhea

• Acute diarrhea

• Chronic diarrhea

• Traveler's diarrhea

• Acute watery diarrhea

• Acute bloody diarrhea

• Acute fatty diarrhea

• Chronic watery diarrhea

• Chronic bloody diarrhea

• Chronic fatty diarrhea

• Acute diarrhea and fever

• Chronic diarrhea and fever

• Acute diarrhea and abdominal pain

• Chronic diarrhea and abdominal pain

• Acute diarrhea and weight loss

• Chronic diarrhea and weight loss

• Acute diarrhea, fever, and abdominal pain

• Chronic diarrhea, fever, and abdominal pain

• Acute diarrhea, abdominal pain, and weight loss

• Chronic diarrhea, abdominal pain, and weight loss

Dumping syndrome

• Nausea, vomiting, diarrhea, fatigue and abdominal pain

• Post-vagotomy complications

• Early dumping syndrome symptoms

• Late dumping syndrome symptoms

Dyspnea

• Dyspnea and fever

• Dyspnea and chest pain

• Dyspnea and cough

• Dyspnea and jugular vein distention

• Dyspnea and cyanosis or clubbing

• Dyspnea and loss of consciousness or agitation

• Dyspnea with normal auscultation

• Dyspnea with stridor

• Dyspnea with wheezing

• Dyspnea with crackle

• Dyspnea with rhonchi

• Dyspnea, fever, and cough

• Dyspnea, fever, and chest pain

• Dyspnea, cough, and cyanosis or clubbing

• Dyspnea, fever, chest pain, cough, and cyanosis or clubbing

Dyspepsia

• Dyspepsia

• Chronic nausea and vomiting

Dysphagia

• Dysphagia

• Dysphagia and weight loss

• Dysphagia and heartburn

• Dysphagia, weight loss and heartburn

E

Electrolyte imbalance

• Hyperkalemia

• Hypernatremia

• Hypokalemia

• Hyponatremia

Esophageal web

• Esophageal web

G

Gastrointestinal bleeding

• Gastrointestinal bleeding

• Upper Gastrointestinal bleeding

• Lower Gastrointestinal bleeding

Gastroesophageal reflux disease (GERD)

• Nausea, vomiting, and heartburn

• Dysphagia, odynophagia, and heart burn

Glomerular disease

• Glomerular disease

H

Hemoptysis

• Hemoptysis and cough

Hyperkalemia

• Hyperkalemia

Hypernatremia

• Hypernatremia

Hyperventilation

• Hyperventilation

Hypoglycemia

• Hypoglycemia

• Autonomic hyperactivity symptoms

• Neurological symptoms in neonates

• Coma and consciousness alterations

Hypokalemia

• Hypokalemia

Hyponatremia

• Hyponatremia

Hypoventilation

• Hypoventilation

I

Insulinoma

• Hypoglycemia

J

Jaundice

• Jaundice

• Jaundice and RUQ pain

• Jaundice and pruritis

• Jaundice and fever

• Jaundice, fever, and RUQ pain

• Jaundice, pruritis and RUQ pain

K

Kaposi's sarcoma

• Kaposi's sarcoma

Kidney stone

• Kidney stone

L

Leukocytosis

• Leukocytosis

Low back pain

• Low back pain

Lung cancer

• Lung cancer

• Cavitary lung lesion

M

Malabsorption

• Malabsorption

Menetrier's disease

• Menetrier's disease

Metabolic acidosis

• Metabolic acidosis

• High anion gap metabolic acidosis

• High osmolar gap metabolic acidosis

• Metabolic acidosis and lactic acidosis

Metabolic alkalosis

• Metabolic alkalosis

Muscle weakness

• Muscle weakness

• Distal muscle weakness

• Inflammatory myopathy

• Muscle weakness and Fever

• Muscle weakness and Myalgia

• Muscle weakness and Gait abnormality

• Muscle weakness and Neuropathy

• Muscle weakness and stiffness

• Muscle weakness and Myoglobinuria

• Muscle weakness and Atrophy

• Proximal muscle weakness

O

Obstructive lung disease

• Obstructive lung disease

Oliguria

• Oliguria

• Oliguria with thirst

• Oliguria with muscle weakness

• Oliguria with vomiting

• Oliguria with diarrhea

• Oliguria with tachypnea

• Oliguria with edema

• Oliguria with fatigue and thirst

• Oliguria with fatigue and tachypnea

• Oliguria with fatigue and edema

• Oliguria with fatigue, vomiting, and diarrhea

• Oliguria with fatigue, somatic pain, vomiting, and diarrhea

• Oliguria with fatigue, somatic pain, vomiting, diarrhea, and edema

Oral lesions

• Oral ulcer

Osteoporosis

• Osteoporosis

P

Pancytopenia

• Pancytopenia

Plasma cell disorder

• Plasma cell disorder

Pharyngitis

• Pharyngitis

Polycystic kidney disease

• Polycystic kidney disease

Polycythemia

• Polycythemia

Polycythemia vera

• Polycythemia vera

Polymyalgia rheumatica

• Fatigue and chronic pain

• Muscle pain

Polymyositis

• Polymyositis

Portal hypertension

• Portal hypertension

Psittacosis

• Psittacosis

Pyloric stenosis

• Pyloric stenosis

Pyuria

• Pyuria

R

Reactive arthritis

• Arthralgia

• Rash and Arthritis

Respiratory acidosis

• Respiratory acidosis

Respiratory alkalosis

• Respiratory alkalosis

Respiratory failure

• Respiratory failure

Restrictive lung disease

• Dyspnea, cough, hemoptysis, and fever

S

Salivary gland swelling

• Salivary gland swelling

SAPHO syndrome

• Bone pain, edema, and erythema

Sialolithiasis

• Salivary gland swelling

Splenomegaly

• Splenomegaly

Stomach cancer

• Abdominal pain, weight loss, and loss of appetite

T

Thrombocytopenia

• Thrombocytopenia

Thrombocytosis

• Thrombocytosis

Tongue cancer

• Tongue cancer

U

Urinary incontinence

• Urge incontinence

• Stress incontinence

• Functional incontinence

• Overflow incontinence

• Mixed incontinence

V

Vasculitis

Large-sized vessel vasculitis

• Large-sized vessel vasculitis

• Large-sized vessel vasculitis with weight loss

• Large-sized vessel vasculitis with arthralgia

• Large-sized vessel vasculitis with claudication

• Large-sized vessel vasculitis with hypertension

Medium-sized vessel vasculitis

• Medium-sized vessel vasculitis

• Medium-sized vessel vasculitis with headache

• Medium-sized vessel vasculitis with fever

• Medium-sized vessel vasculitis with weight loss

• Medium-sized vessel vasculitis with arthralgia

• Medium-sized vessel vasculitis with claudication

• Medium-sized vessel vasculitis with bruit

• Medium-sized vessel vasculitis with hypertension

• Medium-sized vessel vasculitis with focal neurological sign

• Medium-sized vessel vasculitis with headache, fever, and focal neurological sign

• Medium-sized vessel vasculitis with headache, fever, weight loss, and arthralgia

• Medium-sized vessel vasculitis with headache, fever, weight loss, arthralgia, claudication, bruit, and hypertension

Small-sized vessel vasculitis

• Small-sized vessel vasculitis

• Small-sized vessel vasculitis with headache

• Small-sized vessel vasculitis with fever

• Small-sized vessel vasculitis with weight loss

• Small-sized vessel vasculitis with arthralgia

• Small-sized vessel vasculitis with claudication

• Small-sized vessel vasculitis with hypertension

• Small-sized vessel vasculitis with focal neurological sign

• Small-sized vessel vasculitis with fever and headache

• Small-sized vessel vasculitis with fever and weight loss

• Small-sized vessel vasculitis with fever and arthralgia

• Small-sized vessel vasculitis with fever and claudication

• Small-sized vessel vasculitis with fever and focal neurological sign

• Small-sized vessel vasculitis with fever, weight loss, and arthralgia

• Small-sized vessel vasculitis with fever, weight loss, and focal neurological sign

• Small-sized vessel vasculitis with fever, headache, weight loss, arthralgia, and claudication

• Small-sized vessel vasculitis with fever, headache,weight loss, arthralgia, claudication, hypertension, and focal neurological sign

Variable-sized vessel vasculitis

• Variable-sized vessel vasculitis

Single organ vasculitis

• Single organ vasculitis

VIPoma

• Chronic watery diarrhea

W

Wheezing

• Wheezing

• Wheezing and cough

• Wheezing and fever

• Wheezing and slurred speech

• Wheezing, cough, and fever

Z

Zenker's diverticulum

• Zenker's diverticulum