Cervical cancer other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
There are other important diagnostic tools for diagnosing cervical neoplasia, these are include colposcopy and biopsy, cold knife conization, endocervical curettage. Cervical biopsy is the confirmatory test for the diagnosis of cervical cancer or pre-cancer, this can be done in doctor's office via colposcopy. | There are other important diagnostic tools for diagnosing cervical neoplasia, these are include [[colposcopy]] and [[biopsy]], cold knife conization, endocervical [[curettage]]. Cervical biopsy is the confirmatory test for the diagnosis of cervical cancer or pre-cancer, this can be done in doctor's office via [[colposcopy]]. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Biopsy=== | ===Biopsy=== | ||
* This is often done through [[colposcopy]], a magnified visual inspection of the cervix aided by using an [[acetic acid]] solution to highlight abnormal cells on the surface of the cervix. | * This is often done through [[colposcopy]], a magnified visual inspection of the cervix aided by using an [[acetic acid]] solution to highlight abnormal cells on the surface of the [[cervix]]. | ||
* Other diagnostic procedures are [[loop electrical excision procedure]] (LEEP) and [[conization]], in which the inner lining of the cervix is removed to be examined pathologically. These are carried out if the biopsy confirms severe [[cervical intraepithelial neoplasia]].<ref name="pmid7920057">{{cite journal |vauthors=Chen RJ, Chang DY, Yen ML, Chow SN, Huang SC |title=Loop electrosurgical excision procedure for conization of the uterine cervix |journal=J. Formos. Med. Assoc. |volume=93 |issue=3 |pages=196–9 |date=March 1994 |pmid=7920057 |doi= |url=}}</ref> | * Other diagnostic procedures are [[loop electrical excision procedure]] (LEEP) and [[conization]], in which the inner lining of the cervix is removed to be examined pathologically. These are carried out if the biopsy confirms severe [[cervical intraepithelial neoplasia]].<ref name="pmid7920057">{{cite journal |vauthors=Chen RJ, Chang DY, Yen ML, Chow SN, Huang SC |title=Loop electrosurgical excision procedure for conization of the uterine cervix |journal=J. Formos. Med. Assoc. |volume=93 |issue=3 |pages=196–9 |date=March 1994 |pmid=7920057 |doi= |url=}}</ref> | ||
*'''[[Biopsy]]''': Most women have tissue removed in the doctor's office with local anesthesia. A pathologist checks the tissue under a microscope for abnormal cells. | *'''[[Biopsy]]''': Most women have tissue removed in the doctor's office with local anesthesia. A [[pathologist]] checks the tissue under a microscope for abnormal cells. | ||
**'''Punch biopsy:''' The doctor uses a sharp tool to pinch off small samples of cervical tissue. | **'''[[Punch biopsy]]:''' The doctor uses a sharp tool to pinch off small samples of [[cervical]] tissue. | ||
**'''Loop electrosurgical excision procedure(LEEP):''' The doctor uses an electric wire loop to slice off a thin, round piece of cervical tissue, this method allows deep excision of the transformation zone. | **'''[[Loop electrosurgical excision procedure]](LEEP):''' The doctor uses an electric wire loop to slice off a thin, round piece of [[cervical]] tissue, this method allows deep excision of the [[transformation zone]]. | ||
**'''Endocervical curettage:''' The doctor uses a curette (a small, spoon-shaped instrument) to scrape a small sample of tissue from the cervix. Some doctors may use a thin, soft brush instead of a curette. | **'''Endocervical [[curettage]]:''' The doctor uses a curette (a small, spoon-shaped instrument) to scrape a small sample of tissue from the cervix. Some doctors may use a thin, soft brush instead of a curette. | ||
**'''Conization:''' A conization, or cold knife cone biopsy, cone shaped samples are removed from cervix and allows for accurate examination of biopsy speciemen by pathologists.This can be done in doctor's office or in the hospital under general anesthesia. Most significant complication of this method is hemorrhage. There is relative contraindication for pregnant women and also conization increase the risk of preterm birth. <ref>{{cite journal|doi=10.1097/IGC.0000000000000991.}}</ref><ref name="pmid22899563">{{cite journal |vauthors=Castanon A, Brocklehurst P, Evans H, Peebles D, Singh N, Walker P, Patnick J, Sasieni P |title=Risk of preterm birth after treatment for cervical intraepithelial neoplasia among women attending colposcopy in England: retrospective-prospective cohort study |journal=BMJ |volume=345 |issue= |pages=e5174 |date=August 2012 |pmid=22899563 |pmc=3421237 |doi=10.1136/bmj.e5174 |url=}}</ref> | **'''[[Conization]]:''' A conization, or cold knife [[cone biopsy]], cone shaped samples are removed from [[cervix]] and allows for accurate examination of biopsy speciemen by [[pathologists]].This can be done in doctor's office or in the hospital under general anesthesia. Most significant complication of this method is [[hemorrhage]]. There is relative contraindication for pregnant women and also [[conization]] increase the risk of [[preterm birth]]. <ref>{{cite journal|doi=10.1097/IGC.0000000000000991.}}</ref><ref name="pmid22899563">{{cite journal |vauthors=Castanon A, Brocklehurst P, Evans H, Peebles D, Singh N, Walker P, Patnick J, Sasieni P |title=Risk of preterm birth after treatment for cervical intraepithelial neoplasia among women attending colposcopy in England: retrospective-prospective cohort study |journal=BMJ |volume=345 |issue= |pages=e5174 |date=August 2012 |pmid=22899563 |pmc=3421237 |doi=10.1136/bmj.e5174 |url=}}</ref> | ||
== See also== | == See also== | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Gynecology]] | [[Category:Gynecology]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Medicine]] | [[Category:Medicine]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]
Overview
There are other important diagnostic tools for diagnosing cervical neoplasia, these are include colposcopy and biopsy, cold knife conization, endocervical curettage. Cervical biopsy is the confirmatory test for the diagnosis of cervical cancer or pre-cancer, this can be done in doctor's office via colposcopy.
Other Diagnostic Studies
Biopsy
- This is often done through colposcopy, a magnified visual inspection of the cervix aided by using an acetic acid solution to highlight abnormal cells on the surface of the cervix.
- Other diagnostic procedures are loop electrical excision procedure (LEEP) and conization, in which the inner lining of the cervix is removed to be examined pathologically. These are carried out if the biopsy confirms severe cervical intraepithelial neoplasia.[1]
- Biopsy: Most women have tissue removed in the doctor's office with local anesthesia. A pathologist checks the tissue under a microscope for abnormal cells.
- Punch biopsy: The doctor uses a sharp tool to pinch off small samples of cervical tissue.
- Loop electrosurgical excision procedure(LEEP): The doctor uses an electric wire loop to slice off a thin, round piece of cervical tissue, this method allows deep excision of the transformation zone.
- Endocervical curettage: The doctor uses a curette (a small, spoon-shaped instrument) to scrape a small sample of tissue from the cervix. Some doctors may use a thin, soft brush instead of a curette.
- Conization: A conization, or cold knife cone biopsy, cone shaped samples are removed from cervix and allows for accurate examination of biopsy speciemen by pathologists.This can be done in doctor's office or in the hospital under general anesthesia. Most significant complication of this method is hemorrhage. There is relative contraindication for pregnant women and also conization increase the risk of preterm birth. [2][3]
See also
References
- ↑ Chen RJ, Chang DY, Yen ML, Chow SN, Huang SC (March 1994). "Loop electrosurgical excision procedure for conization of the uterine cervix". J. Formos. Med. Assoc. 93 (3): 196–9. PMID 7920057.
- ↑ . doi:10.1097/IGC.0000000000000991. Check
|doi=value (help). Missing or empty|title=(help) - ↑ Castanon A, Brocklehurst P, Evans H, Peebles D, Singh N, Walker P, Patnick J, Sasieni P (August 2012). "Risk of preterm birth after treatment for cervical intraepithelial neoplasia among women attending colposcopy in England: retrospective-prospective cohort study". BMJ. 345: e5174. doi:10.1136/bmj.e5174. PMC 3421237. PMID 22899563.