Sexcord/ stromal ovarian tumors classification: Difference between revisions
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{{Sexcord/ stromal ovarian tumors}} | {{Sexcord/ stromal ovarian tumors}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{M.N}} | ||
==Overview== | ==Overview== | ||
Sexcord/ stromal ovarian tumors may be classified according to WHO into 3 subtypes: | Sexcord/ stromal ovarian tumors may be classified according to [[WHO]] into 3 subtypes: pure stromal tumors, pure sexcord tumors, mixed stromal and sexcord tumors. [[Histological]] [[classification]] of sexcord-stromal ovarian tumors includes [[granulosa]] stromal cell tumors, [[Sertoli-Leydig cell tumour|sertoli leydig cell tumors]], gynandroblastoma, and unclassified. | ||
==Classification== | ==Classification== | ||
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** Sclerosing [[stromal]] [[tumor]] | ** Sclerosing [[stromal]] [[tumor]] | ||
** [[Signet ring|Signet-ring]] [[stromal]] [[tumor]] | ** [[Signet ring|Signet-ring]] [[stromal]] [[tumor]] | ||
** [[Microcytic|Microcy]]<nowiki/>stic [[stromal]] [[tumor]] | **<nowiki/>[[Microcytic|Microcy]]<nowiki/>stic [[stromal]] [[tumor]] | ||
** [[Leydig cell tumor]] | ** [[Leydig cell tumor|Leydig]] <nowiki/>[[Leydig cell tumor|cell tumor]] | ||
** Steroid cell tumor | ** Steroid cell tumor | ||
** Steroid cell tumor, [[malignant]] | ** Steroid cell tumor, [[malignant]] | ||
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** Retiform with heterologous elements | ** Retiform with heterologous elements | ||
* Sex cord-stromal tumours, NOS | * Sex cord-stromal tumours, NOS | ||
|- | |||
| colspan="2" |NOS, not otherwise specified | |||
|} | |} | ||
{| class="wikitable" | {| class="wikitable" | ||
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|'''Granulosa‐stromal cell tumors''' | |'''Granulosa‐stromal cell tumors''' | ||
| | | | ||
*Granulosa cell tumor | *[[Granulosa cell tumor]] | ||
*Tumors in the | *[[Tumors]] in the [[thecoma]]‐[[fibroma]] group | ||
**Thecoma | **[[Thecoma]] | ||
**Fibroma | **[[Fibroma]] | ||
**Unclassified | **Unclassified | ||
|- | |- | ||
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| | | | ||
*Well‐differentiated | *Well‐differentiated | ||
**Sertoli cell tumor | **[[Sertoli Cell Tumor|Sertoli cell tumor]] | ||
**Sertoli cell tumor with lipid storage | **[[Sertoli Cell Tumor|Sertoli cell tumor]] with [[lipid]] storage | ||
**Sertoli–Leydig cell tumor (tubular adenoma with Leydig cells) | **[[Sertoli-Leydig cell tumour|Sertoli–Leydig cell tumor]] (tubular adenoma with [[Leydig cells]]) | ||
*Of intermediate differentiation | *Of intermediate differentiation | ||
*Poorly differentiated (sarcomatoid) | *Poorly differentiated (sarcomatoid) | ||
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'''International Agency for Research on Cancer Histologic Groups of Ovarian Tumors''' | '''International Agency for Research on Cancer Histologic Groups of Ovarian Tumors''' | ||
Classification from '''International agency for research on cancer''' is summarized in the table: <ref name="pmid26894303">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications |journal=Arch. Gynecol. Obstet. |volume=293 |issue=4 |pages=695–700 |date=April 2016 |pmid=26894303 |doi=10.1007/s00404-016-4035-8 |url=}}</ref><ref name="urlonlinelibrary.wiley.com">{{cite web |url=https://onlinelibrary.wiley.com/doi/pdf/10.1002/cncr.11345 |title=onlinelibrary.wiley.com |format= |work= |accessdate=}}</ref><ref name="pmid26556905">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer |journal=Geburtshilfe Frauenheilkd |volume=75 |issue=10 |pages=1021–1027 |date=October 2015 |pmid=26556905 |pmc=4629993 |doi=10.1055/s-0035-1558079 |url=}}</ref> | Classification from '''International agency for research on cancer''' is summarized in the table: <ref name="pmid26894303">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications |journal=Arch. Gynecol. Obstet. |volume=293 |issue=4 |pages=695–700 |date=April 2016 |pmid=26894303 |doi=10.1007/s00404-016-4035-8 |url=}}</ref><ref name="urlonlinelibrary.wiley.com">{{cite web |url=https://onlinelibrary.wiley.com/doi/pdf/10.1002/cncr.11345 |title=onlinelibrary.wiley.com |format= |work= |accessdate=}}</ref><ref name="pmid26556905">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer |journal=Geburtshilfe Frauenheilkd |volume=75 |issue=10 |pages=1021–1027 |date=October 2015 |pmid=26556905 |pmc=4629993 |doi=10.1055/s-0035-1558079 |url=}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
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|- | |- | ||
| | | | ||
* Carcinoma | * [[Carcinoma]] | ||
** Serous carcinoma | ** [[Serous]] [[carcinoma]] | ||
** Mucinous | ** [[Mucinous carcinoma]] | ||
** Endometrioid carcinoma | ** [[Endometrial cancer|Endometrioid carcinoma]] | ||
** Clear cell carcinoma | ** [[Clear cell endometrial cancer|Clear cell carcinoma]] | ||
** Adenocarcinoma NOS | ** Adenocarcinoma NOS | ||
** Other specified carcinomas | ** Other specified carcinomas | ||
** Unspecified carcinoma | ** Unspecified carcinoma | ||
* Sex cord-stromal tumors | * Sex cord-stromal tumors | ||
* Germ cell tumors | * [[Germ cell tumors]] | ||
* Other specified cancers (including malignant Brenner tumor, mullerian mixed tumor, and carcinosarcoma) | * Other specified cancers (including malignant [[Brenner tumor of ovary|Brenner tumor]], mullerian mixed tumor, and carcinosarcoma) | ||
* Unspecified cancer | * Unspecified cancer | ||
|} | |} | ||
Latest revision as of 17:24, 29 May 2019
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Sexcord/ stromal ovarian tumors Microchapters |
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Differentiating Sexcord/ Stromal Ovarian Tumors from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Sexcord/ stromal ovarian tumors classification On the Web |
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American Roentgen Ray Society Images of Sexcord/ stromal ovarian tumors classification |
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Risk calculators and risk factors for Sexcord/ stromal ovarian tumors classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2]
Overview
Sexcord/ stromal ovarian tumors may be classified according to WHO into 3 subtypes: pure stromal tumors, pure sexcord tumors, mixed stromal and sexcord tumors. Histological classification of sexcord-stromal ovarian tumors includes granulosa stromal cell tumors, sertoli leydig cell tumors, gynandroblastoma, and unclassified.
Classification
WHO classification for ovarian sex cord-stromal tumors:[1][2][3][4][5]
- Pure stromal tumors
- Fibroma
- Cellular fibroma
- Thecoma
- Luteinized thecoma associated with sclerosing peritonitis
- Fibrosarcoma
- Sclerosing stromal tumor
- Signet-ring stromal tumor
- Microcystic stromal tumor
- Leydig cell tumor
- Steroid cell tumor
- Steroid cell tumor, malignant
- Pure sex cord tumors
- Adult granulosa cell tumor
- Juvenile granulosa cell tumor
- Sertoli cell tumor
- Sex cord tumor with annular tubules
- Mixed sex cord-stromal tumors
- Sertoli-Leydig cell tumors
- Well-differentiated
- Moderately differentiated with heterologous elements
- Poorly differentiated with heterologous elements
- Retiform with heterologous elements
- Sex cord-stromal tumours, NOS
- Sertoli-Leydig cell tumors
| Types | Subtypes |
| Pure stromal tumors |
|
| Pure sex cord tumors |
|
| Mixed sex cord-stromal tumors |
|
| NOS, not otherwise specified | |
| Types | Subtypes |
| Granulosa‐stromal cell tumors | |
| Sertoli–Leydig cell tumors |
|
| Gynandroblastoma | No specific subtypes |
| Unclassified | No specific subtypes |
International Agency for Research on Cancer Histologic Groups of Ovarian Tumors
Classification from International agency for research on cancer is summarized in the table: [2][7][3]
| Ovarian tumors |
|---|
|
References
- ↑ 1.0 1.1 Horta M, Cunha TM (2015). "Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists". Diagn Interv Radiol. 21 (4): 277–86. doi:10.5152/dir.2015.34414. PMC 4498422. PMID 26054417.
- ↑ 2.0 2.1 2.2 Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (April 2016). "The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications". Arch. Gynecol. Obstet. 293 (4): 695–700. doi:10.1007/s00404-016-4035-8. PMID 26894303.
- ↑ 3.0 3.1 3.2 Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (October 2015). "Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer". Geburtshilfe Frauenheilkd. 75 (10): 1021–1027. doi:10.1055/s-0035-1558079. PMC 4629993. PMID 26556905.
- ↑ 4.0 4.1 McCluggage WG (August 2011). "Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis". Pathology. 43 (5): 420–32. doi:10.1097/PAT.0b013e328348a6e7. PMID 21716157.
- ↑ 5.0 5.1 Chen, Vivien W.; Ruiz, Bernardo; Killeen, Jeffrey L.; Cot�, Timothy R.; Wu, Xiao Cheng; Correa, Catherine N.; Howe, Holly L. (2003). "Pathology and classification of ovarian tumors". Cancer. 97 (S10): 2631–2642. doi:10.1002/cncr.11345. ISSN 0008-543X. replacement character in
|last4=at position 4 (help) - ↑ Fuller, P.J.; Leung, D.; Chu, S. (2017). "Genetics and genomics of ovarian sex cord-stromal tumors". Clinical Genetics. 91 (2): 285–291. doi:10.1111/cge.12917. ISSN 0009-9163.
- ↑ "onlinelibrary.wiley.com".