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{{Catecholaminergic polymorphic ventricular tachycardia}}
{{Catecholaminergic polymorphic ventricular tachycardia}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}}{{MRV}}
==Overview==
==Overview==
There is no established system for the classification of [disease name].
Catecholaminergic polymorphic ventricular tachycardia can be classified based upon the underlying pathogenic [[mutation]].
 
OR
 
[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
 
OR
 
[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
[Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
If the staging system involves specific and characteristic findings and features:
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
 
OR
 
The staging of [malignancy name] is based on the [staging system].
 
OR
 
There is no established system for the staging of [malignancy name].


==Classification==
==Classification==


There is no established system for the classification of [disease name].
[[CPVT]] may be classified based upon the underlying pathogenic [[mutation]] into the following subtypes:<ref name="Sumitomo2016">{{cite journal|last1=Sumitomo|first1=Naokata|title=Current topics in catecholaminergic polymorphic ventricular tachycardia|journal=Journal of Arrhythmia|volume=32|issue=5|year=2016|pages=344–351|issn=18804276|doi=10.1016/j.joa.2015.09.008}}</ref>
 
OR
 
[Disease name] may be classified according to [classification method] into [number] subtypes/groups:
*[Group1]
*[Group2]
*[Group3]
*[Group4]
 
OR
 
[Disease name] may be classified into [large number > 6] subtypes based on:
*[Classification method 1]
*[Classification method 2]
*[Classification method 3]
 
[Disease name] may be classified into several subtypes based on:  
*[Classification method 1]
*[Classification method 2]
*[Classification method 3]
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
'''If the staging system involves specific and characteristic findings and features:'''
 
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
 
OR
 
The staging of [malignancy name] is based on the [staging system].
 
OR


There is no established system for the staging of [malignancy name].
{| class="wikitable"
|-
! Type
! [[OMIM]]
! Gene
! Protein
! Mode of inheritance
! Locus
|-
| CPVT1
| {{OMIM2|604772}}
| ''[[ryanodine receptor 2|RyR2]]''
| [[Ryanodine receptor 2]]
| [[Autosomal dominant]]
| 1q42.1-q43
|-
| CPVT2
| {{OMIM2|611938}}
| ''[[Calsequestrin|CASQ2]]''
| [[Calsequestrin|Calsequestrin 2]]
| [[Autosomal recessive]]
| 1p13.3-p11
|-
| CPVT3
| {{OMIM2|614021}}
| ''Unknown''
| -
| [[Autosomal recessive]]
| 7p14–p22
|-
| CPVT4
| {{OMIM2|614916}}
| ''[[Calmodulin 1|CALM1]]''
| [[Calmodulin 1]]
| [[Autosomal dominant]]
| 14q32.11
|-
| CPVT5
| {{OMIM2|615441}}
| ''[[TRDN]]''
| [[Triadin]]
| [[Autosomal recessive]]
|  6q22.31
|}


==References==
==References==

Latest revision as of 15:27, 23 July 2020

Catecholaminergic polymorphic ventricular tachycardia Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mounika Reddy Vadiyala, M.B.B.S.[2]

Overview

Catecholaminergic polymorphic ventricular tachycardia can be classified based upon the underlying pathogenic mutation.

Classification

CPVT may be classified based upon the underlying pathogenic mutation into the following subtypes:[1]

Type OMIM Gene Protein Mode of inheritance Locus
CPVT1 604772 RyR2 Ryanodine receptor 2 Autosomal dominant 1q42.1-q43
CPVT2 611938 CASQ2 Calsequestrin 2 Autosomal recessive 1p13.3-p11
CPVT3 614021 Unknown - Autosomal recessive 7p14–p22
CPVT4 614916 CALM1 Calmodulin 1 Autosomal dominant 14q32.11
CPVT5 615441 TRDN Triadin Autosomal recessive 6q22.31

References

  1. ↑ Sumitomo, Naokata (2016). "Current topics in catecholaminergic polymorphic ventricular tachycardia". Journal of Arrhythmia. 32 (5): 344–351. doi:10.1016/j.joa.2015.09.008. ISSN 1880-4276.

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