Pre-eclampsia natural history, complications and prognosis: Difference between revisions
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{{Pre-eclampsia}} | {{Pre-eclampsia}} | ||
{{CMG}}; {{AE}} {{ | {{CMG}}; {{AE}} {{Sara.Zand}} {{Ochuko}} | ||
==Overview== | |||
[[Preeclampsic]] patients are usually asymptomatic and may deteriorate rapidly without any specific signs and symptoms. Early clinical feature after 20 weeks of [[gestation]] include [[blood pressure]] ≥ 140/90 mmHg, [[proteinuria]], evidence of maternal organ involvement. Common complications of [[preeclampsia]] include: [[intrauterin growth retardation]] ([[IUGR]]), [[uteroplacental insufficiency]], [[fetal]] [[asphyxia]] or [[fetal death]], maternal [[seizures]], and [[maternal death]]. Long term complication of [[preeclampsia]] include: [[chronic hypertension]], [[diabetes mellitus]], [[ischemic heart disease]], [[cerebrovascular disease]], [[kidney disease]], [[thromboembolism]], [[hypothyroidism]], and [[impaired memory]]. Prognosis is generally good after [[delivery]] and controlling maternal [[hypertension]]. The five-year mortality rate of the patients with [[preeclampsia]] is approximately 0.4%. | |||
==Natural History, Complications and Prognosis== | |||
*[[Preeclampsic]] patients are usually asymptomatic and may deteriorate rapidly without any specific signs and symptoms. <ref name="BrownMagee2018">{{cite journal|last1=Brown|first1=Mark A.|last2=Magee|first2=Laura A.|last3=Kenny|first3=Louise C.|last4=Karumanchi|first4=S. Ananth|last5=McCarthy|first5=Fergus P.|last6=Saito|first6=Shigeru|last7=Hall|first7=David R.|last8=Warren|first8=Charlotte E.|last9=Adoyi|first9=Gloria|last10=Ishaku|first10=Salisu|title=Hypertensive Disorders of Pregnancy|journal=Hypertension|volume=72|issue=1|year=2018|pages=24–43|issn=0194-911X|doi=10.1161/HYPERTENSIONAHA.117.10803}}</ref> | |||
* Early clinical feature after 20 weeks of [[gestation]] include [[blood pressure]] ≥ 140/90 mmHg, [[proteinuria]], evidence of maternal organ involvement. | |||
*Common complications of [[preeclampsia]] include: | |||
:* [[Intrauterin growth retardation]] ([[IUGR]]) | |||
:* [[Uteroplacental insufficiency]] | |||
:* [[Fetal]] [[asphyxia]] or [[fetal death]] | |||
:* Maternal [[seizures]] | |||
:* [[Maternal death]] | |||
*Long term complication of [[preeclampsia]] include:<ref name="Williams2011">{{cite journal|last1=Williams|first1=David|title=Long-Term Complications of Preeclampsia|journal=Seminars in Nephrology|volume=31|issue=1|year=2011|pages=111–122|issn=02709295|doi=10.1016/j.semnephrol.2010.10.010}}</ref> | |||
* [[ | :* [[Chronic hypertension]] | ||
* [[ | :* [[Diabetes mellitus]] | ||
* [[ | :* [[Ischemic heart disease]] | ||
* [[ | :* [[Cerebrovascular disease]] | ||
* [[ | :* [[Kidney disease]] | ||
* | :* [[Thromboembolism]] | ||
:* [[Hypothyroidism ]] | |||
:* [[Impaired memory]] | |||
*[[Prognosis]] is generally good after [[delivery]] with controlling maternal [[hypertension]]. The 5 year mortality rate of the patients with [[preeclampsia]] is approximately 0.4%.<ref name="Sibai2002">{{cite journal|last1=Sibai|first1=Baha M|title=The Magpie Trial|journal=The Lancet|volume=360|issue=9342|year=2002|pages=1329|issn=01406736|doi=10.1016/S0140-6736(02)11321-3}}</ref> | |||
==References== | ==References== | ||
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[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category: | [[Category:Up-to-date]] | ||
Latest revision as of 14:58, 15 March 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Ogheneochuko Ajari, MB.BS, MS [3]
Overview
Preeclampsic patients are usually asymptomatic and may deteriorate rapidly without any specific signs and symptoms. Early clinical feature after 20 weeks of gestation include blood pressure ≥ 140/90 mmHg, proteinuria, evidence of maternal organ involvement. Common complications of preeclampsia include: intrauterin growth retardation (IUGR), uteroplacental insufficiency, fetal asphyxia or fetal death, maternal seizures, and maternal death. Long term complication of preeclampsia include: chronic hypertension, diabetes mellitus, ischemic heart disease, cerebrovascular disease, kidney disease, thromboembolism, hypothyroidism, and impaired memory. Prognosis is generally good after delivery and controlling maternal hypertension. The five-year mortality rate of the patients with preeclampsia is approximately 0.4%.
Natural History, Complications and Prognosis
- Preeclampsic patients are usually asymptomatic and may deteriorate rapidly without any specific signs and symptoms. [1]
- Early clinical feature after 20 weeks of gestation include blood pressure ≥ 140/90 mmHg, proteinuria, evidence of maternal organ involvement.
- Common complications of preeclampsia include:
- Long term complication of preeclampsia include:[2]
- Prognosis is generally good after delivery with controlling maternal hypertension. The 5 year mortality rate of the patients with preeclampsia is approximately 0.4%.[3]
References
- ↑ Brown, Mark A.; Magee, Laura A.; Kenny, Louise C.; Karumanchi, S. Ananth; McCarthy, Fergus P.; Saito, Shigeru; Hall, David R.; Warren, Charlotte E.; Adoyi, Gloria; Ishaku, Salisu (2018). "Hypertensive Disorders of Pregnancy". Hypertension. 72 (1): 24–43. doi:10.1161/HYPERTENSIONAHA.117.10803. ISSN 0194-911X.
- ↑ Williams, David (2011). "Long-Term Complications of Preeclampsia". Seminars in Nephrology. 31 (1): 111–122. doi:10.1016/j.semnephrol.2010.10.010. ISSN 0270-9295.
- ↑ Sibai, Baha M (2002). "The Magpie Trial". The Lancet. 360 (9342): 1329. doi:10.1016/S0140-6736(02)11321-3. ISSN 0140-6736.