Tremor natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
[[Essential tremor]] and [[Parkinson's disease]] worsens with time, [[treatment]] helps to minimize symptoms. Physiologic tremors and drug-induced tremor do not worsen with time and can be controlled. Tremors may be mild or can be very [[disabling]] for some [[patients]]. [[Patients]] with tremors have shown to have decrease [[quality of life]] [[physically]] and [[mentally]] as compared to [[healthy]] [[population]]. | |||
==Natural history, Complications and Prognosis== | ==Natural history, Complications and Prognosis== | ||
===Natural History=== | |||
* | |||
' | *Tremor is not a life-threatening condition. However, if not symptomatically treated it can cause severe physical, mental and social [[disabilities]] depending on the intensity of tremors. | ||
*[[Patients]] with [[essential tremor]] have shown to have decrease [[quality of life]] [[physically and [[mentally]] as compared to [[healthy]] [[population]]<ref name="pmid16622851">{{cite journal| author=Lorenz D, Schwieger D, Moises H, Deuschl G| title=Quality of life and personality in essential tremor patients. | journal=Mov Disord | year= 2006 | volume= 21 | issue= 8 | pages= 1114-8 | pmid=16622851 | doi=10.1002/mds.20884 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16622851 }} </ref>. | *[[Essential tremor]] and [[Parkinson's disease]] generally worsen with time. [[Physiologic]] tremor and [[drug]] induced tremor do not worsen with time and can be controlled.<ref name="PuschmannWszolek2011">{{cite journal|last1=Puschmann|first1=Andreas|last2=Wszolek|first2=Zbigniew|title=Diagnosis and Treatment of Common Forms of Tremor|journal=Seminars in Neurology|volume=31|issue=01|year=2011|pages=065–077|issn=0271-8235|doi=10.1055/s-0031-1271312}}</ref> | ||
===Complications=== | |||
*Reduces [[quality of life]] | |||
*Can cause social [[disability]]. | |||
*May limit their physical activity | |||
*[[Patients]] with [[essential tremor]] have shown to have decrease [[quality of life]] [[physically]] and [[mentally]] as compared to [[healthy]] [[population|population.]] <ref name="pmid16622851">{{cite journal| author=Lorenz D, Schwieger D, Moises H, Deuschl G| title=Quality of life and personality in essential tremor patients. | journal=Mov Disord | year= 2006 | volume= 21 | issue= 8 | pages= 1114-8 | pmid=16622851 | doi=10.1002/mds.20884 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16622851 }} </ref> | |||
*[[Depression]]<ref name="SmeltereKuzņecovs2017">{{cite journal|last1=Smeltere|first1=Ligita|last2=Kuzņecovs|first2=Vladimirs|last3=Erts|first3=Renārs|title=Depression and social phobia in essential tremor and Parkinson's disease|journal=Brain and Behavior|volume=7|issue=9|year=2017|pages=e00781|issn=21623279|doi=10.1002/brb3.781}}</ref> | |||
===Prognosis=== | |||
*Tremors may be mild or can be very [[disabling]] for some [[patients]]. | |||
*[[Essential tremor]] is a gradually progressing [[disease]].The [[symptoms]] usually worsen with [[age]].<ref name="Elble2013">{{cite journal|last1=Elble|first1=Rodger J.|title=What is Essential Tremor?|journal=Current Neurology and Neuroscience Reports|volume=13|issue=6|year=2013|issn=1528-4042|doi=10.1007/s11910-013-0353-4}}</ref> | |||
*It has been observed that patients suffering from [[essential tremors]] are more likely to develop other forms of [[neurodegenerative]] disorders including, [[Parkinson's disease]], [[Alzheimer's disease]] as compared to average [[population]] especially if [[age]] of onset is after 65 years.<ref name="pmid23105950">{{cite journal| author=Rajput AH, Adler CH, Shill HA, Rajput A| title=Essential tremor is not a neurodegenerative disease. | journal=Neurodegener Dis Manag | year= 2012 | volume= 2 | issue= 3 | pages= 259-268 | pmid=23105950 | doi=10.2217/nmt.12.23 | pmc=3478956 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23105950 }} </ref> | |||
*[[Physiologic]] and [[drug]]-induced tremor with time do not worsen, They can be completely controlled by eliminating the causative drug for [[drug]]-induced tremor or controlling the enhancing factors for [[physiologic]] tremors.<ref name="PuschmannWszolek2011">{{cite journal|last1=Puschmann|first1=Andreas|last2=Wszolek|first2=Zbigniew|title=Diagnosis and Treatment of Common Forms of Tremor|journal=Seminars in Neurology|volume=31|issue=01|year=2011|pages=065–077|issn=0271-8235|doi=10.1055/s-0031-1271312}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | [[Category:Neurology]] | ||
[[Category:Primary care]] | |||
[[Category:Signs and symptoms]] | |||
[[Category:Medicine]] |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zehra Malik, M.B.B.S[2]
Overview
Essential tremor and Parkinson's disease worsens with time, treatment helps to minimize symptoms. Physiologic tremors and drug-induced tremor do not worsen with time and can be controlled. Tremors may be mild or can be very disabling for some patients. Patients with tremors have shown to have decrease quality of life physically and mentally as compared to healthy population.
Natural history, Complications and Prognosis
Natural History
- Tremor is not a life-threatening condition. However, if not symptomatically treated it can cause severe physical, mental and social disabilities depending on the intensity of tremors.
- Essential tremor and Parkinson's disease generally worsen with time. Physiologic tremor and drug induced tremor do not worsen with time and can be controlled.[1]
Complications
- Reduces quality of life
- Can cause social disability.
- May limit their physical activity
- Patients with essential tremor have shown to have decrease quality of life physically and mentally as compared to healthy population. [2]
- Depression[3]
Prognosis
- Tremors may be mild or can be very disabling for some patients.
- Essential tremor is a gradually progressing disease.The symptoms usually worsen with age.[4]
- It has been observed that patients suffering from essential tremors are more likely to develop other forms of neurodegenerative disorders including, Parkinson's disease, Alzheimer's disease as compared to average population especially if age of onset is after 65 years.[5]
- Physiologic and drug-induced tremor with time do not worsen, They can be completely controlled by eliminating the causative drug for drug-induced tremor or controlling the enhancing factors for physiologic tremors.[1]
References
- ↑ 1.0 1.1 Puschmann, Andreas; Wszolek, Zbigniew (2011). "Diagnosis and Treatment of Common Forms of Tremor". Seminars in Neurology. 31 (01): 065–077. doi:10.1055/s-0031-1271312. ISSN 0271-8235.
- ↑ Lorenz D, Schwieger D, Moises H, Deuschl G (2006). "Quality of life and personality in essential tremor patients". Mov Disord. 21 (8): 1114–8. doi:10.1002/mds.20884. PMID 16622851.
- ↑ Smeltere, Ligita; Kuzņecovs, Vladimirs; Erts, Renārs (2017). "Depression and social phobia in essential tremor and Parkinson's disease". Brain and Behavior. 7 (9): e00781. doi:10.1002/brb3.781. ISSN 2162-3279.
- ↑ Elble, Rodger J. (2013). "What is Essential Tremor?". Current Neurology and Neuroscience Reports. 13 (6). doi:10.1007/s11910-013-0353-4. ISSN 1528-4042.
- ↑ Rajput AH, Adler CH, Shill HA, Rajput A (2012). "Essential tremor is not a neurodegenerative disease". Neurodegener Dis Manag. 2 (3): 259–268. doi:10.2217/nmt.12.23. PMC 3478956. PMID 23105950.