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==Overview==
==Overview==
[[Head]] [[MRI]] may be helpful in the [[diagnosis]] of the cause of amnesia in some cases including, [[Alzheimer's disease]], or [[brain]] [[trauma]]. In majority of the cases of amnesia the [[brain]] appears normal on [[MRI]].


==MRI==
==MRI==
*[[Psychogenic amnesia]] is defined by the lack of structural damage to the brain, but upon [[Medical imaging|functional imaging]], abnormal brain activity can be seen. Tests using [[functional magnetic resonance imaging]] suggest that patients with psychogenic amnesia are unable to retrieve emotional memories normally during the amnesic period, suggesting that changes in the limbic functions are related to the symptoms of psychogenic amnesia.<ref name = Yang>{{cite journal |author=Yang JC, Jeong GW, Lee MS, ''et al'' |title=Functional MR imaging of psychogenic amnesia: a case report |journal=Korean J Radiol |volume=6 |issue=3 |pages=196–9 |year=2005 |pmid=16145296 |doi=}}</ref>
*[[Psychogenic amnesia]] is defined by the lack of structural damage to the brain, but upon [[Medical imaging|functional imaging]], abnormal brain activity can be seen. Tests using [[functional magnetic resonance imaging]] suggest that patients with psychogenic amnesia are unable to retrieve emotional memories normally during the amnesic period, suggesting that changes in the limbic functions are related to the symptoms of psychogenic amnesia.<ref name = Yang>{{cite journal |author=Yang JC, Jeong GW, Lee MS, ''et al'' |title=Functional MR imaging of psychogenic amnesia: a case report |journal=Korean J Radiol |volume=6 |issue=3 |pages=196–9 |year=2005 |pmid=16145296 |doi=}}</ref>
*In transient [[epileptic]] amnesia [[MRI]] is usually normal. However, in some [[patients]] [[frontal]] and [[temporal lobe]] abnormalities have been observed.<ref name="pmid31555199">{{cite journal| author=Ramanan VK, Morris KA, Graff-Radford J, Jones DT, Burkholder DB, Britton JW | display-authors=etal| title=Transient Epileptic Amnesia: A Treatable Cause of Spells Associated With Persistent Cognitive Symptoms. | journal=Front Neurol | year= 2019 | volume= 10 | issue=  | pages= 939 | pmid=31555199 | doi=10.3389/fneur.2019.00939 | pmc=6724577 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31555199  }} </ref>
*In transient [[epileptic]] amnesia [[MRI]] is usually normal. However, in some [[patients]] [[frontal]] and [[temporal lobe]] abnormalities have been observed.<ref name="pmid31555199">{{cite journal| author=Ramanan VK, Morris KA, Graff-Radford J, Jones DT, Burkholder DB, Britton JW | display-authors=etal| title=Transient Epileptic Amnesia: A Treatable Cause of Spells Associated With Persistent Cognitive Symptoms. | journal=Front Neurol | year= 2019 | volume= 10 | issue=  | pages= 939 | pmid=31555199 | doi=10.3389/fneur.2019.00939 | pmc=6724577 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31555199  }} </ref>
*[[Brain]] [[MRI]] findings suggestive of [[Alzheimer's disease]] include, reduction in [[hippocampal]] volume and [[atrophy]]  of [[medial]] [[temporal lobe]] <ref name="pmid22951070">{{cite journal| author=Whitwell JL, Dickson DW, Murray ME, Weigand SD, Tosakulwong N, Senjem ML et al.| title=Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study. | journal=Lancet Neurol | year= 2012 | volume= 11 | issue= 10 | pages= 868-77 | pmid=22951070 | doi=10.1016/S1474-4422(12)70200-4 | pmc=3490201 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22951070  }} </ref> <ref name="pmid1643466">{{cite journal| author=Brook RH| title=Improving practice: the clinician's role. | journal=Br J Surg | year= 1992 | volume= 79 | issue= 7 | pages= 606-7 | pmid=1643466 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1643466  }} </ref> <ref name="pmid17923614">{{cite journal| author=Barkhof F, Polvikoski TM, van Straaten EC, Kalaria RN, Sulkava R, Aronen HJ et al.| title=The significance of medial temporal lobe atrophy: a postmortem MRI study in the very old. | journal=Neurology | year= 2007 | volume= 69 | issue= 15 | pages= 1521-7 | pmid=17923614 | doi=10.1212/01.wnl.0000277459.83543.99 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17923614  }} </ref>


==References==
==References==

Latest revision as of 01:53, 25 March 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zehra Malik, M.B.B.S[2]

Overview

Head MRI may be helpful in the diagnosis of the cause of amnesia in some cases including, Alzheimer's disease, or brain trauma. In majority of the cases of amnesia the brain appears normal on MRI.

MRI

References

  1. Yang JC, Jeong GW, Lee MS; et al. (2005). "Functional MR imaging of psychogenic amnesia: a case report". Korean J Radiol. 6 (3): 196–9. PMID 16145296.
  2. Ramanan VK, Morris KA, Graff-Radford J, Jones DT, Burkholder DB, Britton JW; et al. (2019). "Transient Epileptic Amnesia: A Treatable Cause of Spells Associated With Persistent Cognitive Symptoms". Front Neurol. 10: 939. doi:10.3389/fneur.2019.00939. PMC 6724577 Check |pmc= value (help). PMID 31555199.
  3. Whitwell JL, Dickson DW, Murray ME, Weigand SD, Tosakulwong N, Senjem ML; et al. (2012). "Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study". Lancet Neurol. 11 (10): 868–77. doi:10.1016/S1474-4422(12)70200-4. PMC 3490201. PMID 22951070.
  4. Brook RH (1992). "Improving practice: the clinician's role". Br J Surg. 79 (7): 606–7. PMID 1643466.
  5. Barkhof F, Polvikoski TM, van Straaten EC, Kalaria RN, Sulkava R, Aronen HJ; et al. (2007). "The significance of medial temporal lobe atrophy: a postmortem MRI study in the very old". Neurology. 69 (15): 1521–7. doi:10.1212/01.wnl.0000277459.83543.99. PMID 17923614.

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