Eczema laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Doing a routine laboratory testing for [[eczema]] is not mandatory. Although an elevated Level of [[IgE]] is associated with [[eczema]], it is not specific to this [[disease]]. Several other [[medical conditions]] manifest with elevated [[IgE]] levels such as [[allergy]], [[parasitic]] [[infections]], [[autoimmune diseases]], and certain [[carcinomas]]. <ref name="pmid24290431">{{cite journal| author=Eichenfield LF, Tom WL, Chamlin SL, Feldman SR, Hanifin JM, Simpson EL | display-authors=etal| title=Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. | journal=J Am Acad Dermatol | year= 2014 | volume= 70 | issue= 2 | pages= 338-51 | pmid=24290431 | doi=10.1016/j.jaad.2013.10.010 | pmc=4410183 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24290431 }} </ref> <ref name="pmid23473856">{{cite journal| author=Kabashima K| title=New concept of the pathogenesis of atopic dermatitis: interplay among the barrier, allergy, and pruritus as a trinity. | journal=J Dermatol Sci | year= 2013 | volume= 70 | issue= 1 | pages= 3-11 | pmid=23473856 | doi=10.1016/j.jdermsci.2013.02.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23473856 }} </ref> <ref name="pmid17040428">{{cite journal| author=Murat-Susić S, Lipozencić J, Zizić V, Husar K, Marinović B| title=Serum eosinophil cationic protein in children with atopic dermatitis. | journal=Int J Dermatol | year= 2006 | volume= 45 | issue= 10 | pages= 1156-60 | pmid=17040428 | doi=10.1111/j.1365-4632.2006.02865.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17040428 }} </ref> <ref name="pmid17579279">{{cite journal| author=Schulte-Herbrüggen O, Fölster-Holst R, von Elstermann M, Augustin M, Hellweg R| title=Clinical relevance of nerve growth factor serum levels in patients with atopic dermatitis and psoriasis. | journal=Int Arch Allergy Immunol | year= 2007 | volume= 144 | issue= 3 | pages= 211-6 | pmid=17579279 | doi=10.1159/000103994 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17579279 }} </ref> | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
*An elevated [[IgE]] level can also be associated with eczema. | *An elevated [[IgE]] level can also be associated with eczema. | ||
*Some ''in vitro'' skin tests may be done when suspecting an [[eczema]]. <ref name="pmid22805051">{{cite journal| author=Ring J, Alomar A, Bieber T, Deleuran M, Fink-Wagner A, Gelmetti C | display-authors=etal| title=Guidelines for treatment of atopic eczema (atopic dermatitis) part I. | journal=J Eur Acad Dermatol Venereol | year= 2012 | volume= 26 | issue= 8 | pages= 1045-60 | pmid=22805051 | doi=10.1111/j.1468-3083.2012.04635.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22805051 }} </ref> <ref name="pmid23374261">{{cite journal| author=Schneider L, Tilles S, Lio P, Boguniewicz M, Beck L, LeBovidge J | display-authors=etal| title=Atopic dermatitis: a practice parameter update 2012. | journal=J Allergy Clin Immunol | year= 2013 | volume= 131 | issue= 2 | pages= 295-9.e1-27 | pmid=23374261 | doi=10.1016/j.jaci.2012.12.672 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23374261 }} </ref> | |||
**[[Skin prick testing]] | |||
**[[Patch testing]] | |||
**[[Food allergy testing]] | |||
==References== | ==References== | ||
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Latest revision as of 18:28, 14 July 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.
Overview
Doing a routine laboratory testing for eczema is not mandatory. Although an elevated Level of IgE is associated with eczema, it is not specific to this disease. Several other medical conditions manifest with elevated IgE levels such as allergy, parasitic infections, autoimmune diseases, and certain carcinomas. [1] [2] [3] [4]
Laboratory Findings
- An elevated IgE level can also be associated with eczema.
- Some in vitro skin tests may be done when suspecting an eczema. [5] [6]
References
- ↑ Eichenfield LF, Tom WL, Chamlin SL, Feldman SR, Hanifin JM, Simpson EL; et al. (2014). "Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis". J Am Acad Dermatol. 70 (2): 338–51. doi:10.1016/j.jaad.2013.10.010. PMC 4410183. PMID 24290431.
- ↑ Kabashima K (2013). "New concept of the pathogenesis of atopic dermatitis: interplay among the barrier, allergy, and pruritus as a trinity". J Dermatol Sci. 70 (1): 3–11. doi:10.1016/j.jdermsci.2013.02.001. PMID 23473856.
- ↑ Murat-Susić S, Lipozencić J, Zizić V, Husar K, Marinović B (2006). "Serum eosinophil cationic protein in children with atopic dermatitis". Int J Dermatol. 45 (10): 1156–60. doi:10.1111/j.1365-4632.2006.02865.x. PMID 17040428.
- ↑ Schulte-Herbrüggen O, Fölster-Holst R, von Elstermann M, Augustin M, Hellweg R (2007). "Clinical relevance of nerve growth factor serum levels in patients with atopic dermatitis and psoriasis". Int Arch Allergy Immunol. 144 (3): 211–6. doi:10.1159/000103994. PMID 17579279.
- ↑ Ring J, Alomar A, Bieber T, Deleuran M, Fink-Wagner A, Gelmetti C; et al. (2012). "Guidelines for treatment of atopic eczema (atopic dermatitis) part I." J Eur Acad Dermatol Venereol. 26 (8): 1045–60. doi:10.1111/j.1468-3083.2012.04635.x. PMID 22805051.
- ↑ Schneider L, Tilles S, Lio P, Boguniewicz M, Beck L, LeBovidge J; et al. (2013). "Atopic dermatitis: a practice parameter update 2012". J Allergy Clin Immunol. 131 (2): 295-9.e1-27. doi:10.1016/j.jaci.2012.12.672. PMID 23374261.