Template:Antithrombotics: Difference between revisions

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{{Navbox
{{Navbox
| name = Antithrombotics
| name = Antithrombotics
| title = [[Antithrombotic]]s ([[thrombolytic drug|thrombolytics]], [[anticoagulant]]s and [[antiplatelet drug]]s) ([[ATC code B01|B01]])
| title = [[Antithrombotic]]s ([[Thrombolytic drug|thrombolytics]], [[anticoagulant]]s and [[antiplatelet drug]]s) ([[ATC code B01|B01]])
| groupstyle = background:MistyRose;
| state = {{{state<includeonly>|autocollapse</includeonly>}}}
| bodyclass = hlist


| group1 = [[Antiplatelet drug]]s
| group1 = [[Antiplatelet drug]]s
| list1 = {{Navbox subgroup
| list1 = {{Navbox|child
  | groupstyle = background-color: MistyRose


| group1 = [[Glycoprotein IIb/IIIa inhibitors]]
  | group1 = [[Glycoprotein IIb/IIIa inhibitors]]
| list1 = [[Abciximab]] [[Eptifibatide]] [[Tirofiban]]
  | list1 =
* [[Abciximab]]
* [[Eptifibatide]]
* [[Orbofiban]]
* [[Roxifiban]]
* [[Sibrafiban]]<sup>§</sup>
* [[Tirofiban]]


| group2 = [[ADP receptor]]/[[P2Y12|P2Y<sub>12</sub>]] inhibitors
  | group2 = [[P2Y12|ADP receptor/P2Y<sub>12</sub>]] [[Adenosine diphosphate receptor inhibitor|inhibitors]]
| list2 = ([[Thienopyridine]]s[[Clopidogrel]] [[Ticlopidine]] [[Prasugrel]]
  | list2 =
* [[Thienopyridine]]s
** [[Clopidogrel]]
** [[Prasugrel]]
** [[Ticlopidine]]
* [[Nucleotide]]/[[nucleoside]] analogs
** [[Cangrelor]]
** [[Elinogrel]]
** [[Ticagrelor]]


| group3 = [[Prostaglandin analogue]] ([[Prostacyclin|PGI2]])
  | group3 = [[Prostaglandin analogue]] ([[Prostacyclin|PGI2]])
| list3 = [[Beraprost]] [[Prostacyclin]] [[Iloprost]] [[Treprostinil]]
  | list3 =
* [[Beraprost]]
* [[Iloprost]]
* [[Prostacyclin]]
* [[Treprostinil]]


| group4 = [[Mechanism of action of aspirin|COX inhibitors]]
  | group4 = [[Mechanism of action of aspirin|COX inhibitors]]
| list4 = [[Aspirin|Acetylsalicylic acid/Aspirin]] # [[Aloxiprin]] [[Carbasalate calcium]]
  | list4 =
* [[Aspirin|Acetylsalicylic acid/Aspirin]]<sup>#</sup>
* [[Aloxiprin]]
* [[Carbasalate calcium]]
* [[Indobufen]]
* [[Triflusal]]


| group5 = Other
  | group5 = [[Thromboxane inhibitors]]
| list5 = [[Ditazole]] [[Cloricromen]] [[Dipyridamole]] •  [[Indobufen]] [[Picotamide]] [[Triflusal]]
  | list5 =
* [[Thromboxane synthase inhibitors]]
** [[Dipyridamole]] ([[Acetylsalicylic acid/dipyridamole|+ aspirin]])
** [[Picotamide]]
** [[Terbogrel]]
* [[Thromboxane receptor antagonist|Receptor antagonist]]s
** [[Terbogrel]]
** [[Terutroban]]<sup>§</sup>


}}
  | group6 = [[Phosphodiesterase inhibitor]]s
  | list6 =
* [[Cilostazol]]
* [[Dipyridamole]]
* [[Triflusal]]


| group2 = [[Anticoagulant]]s
  | group7 = Other
|  list2 = {{Navbox subgroup
  | list7 =
  | groupstyle = background-color: MistyRose
* [[Cloricromen]]
* [[Ditazole]]
* [[Vorapaxar]]


  | group1 = [[Vitamin K antagonist]]s<BR>(inhibit [[Thrombin|II]], [[Factor VII|VII]], [[Factor IX|IX]], [[Factor X|X]])
  }}
  | list1 = ''[[coumarin]]s:'' [[Acenocoumarol]] • [[Coumatetralyl]] • [[Dicoumarol]] (Dicumarol) • [[Ethyl biscoumacetate]] • [[Phenprocoumon]] • [[Warfarin]]


''[[1,3-indandione]]s:'' [[Clorindione]] • [[Diphenadione]] • [[Phenindione]]
| group2 = [[Anticoagulant]]s
| list2 = {{Navbox|child
  | evenodd = swap


''other:'' [[Tioclomarol]]  
  | group1 = [[Vitamin K antagonist]]s<br />(inhibit [[Thrombin|II]], [[Factor VII|VII]], [[Factor IX|IX]], [[Factor X|X]])
  | list1 =
* [[Coumarin]]s: [[Acenocoumarol]]
* [[Coumatetralyl]]
* [[Dicoumarol]]
* [[Ethyl biscoumacetate]]
* [[Phenprocoumon]]
* [[Warfarin]]<sup>#</sup>
* [[1,3-Indandione]]s: [[Clorindione]]
* [[Diphenadione]]
* [[Phenindione]]
* Other: [[Tioclomarol]]


| group2 = [[Factor Xa]] inhibitors<BR>(with some II inhibition)
  | group2 = [[Factor Xa]] inhibitors<br />(with some II inhibition)
| list2 = {{Navbox subgroup
  | list2 = {{Navbox|child
  | groupstyle = background-color: MistyRose


| group1 = [[Heparin]] group/<BR>[[glycosaminoglycan]]s/<BR>(bind [[antithrombin]])
    | group1 = [[Heparin]] group/<br />[[glycosaminoglycan]]s/<br />(bind [[antithrombin]])
| list1 = ''[[low molecular weight heparin]]'' ([[Bemiparin]], [[Certoparin]], [[Dalteparin]], [[Enoxaparin sodium|Enoxaparin]], [[Nadroparin]], [[Parnaparin]], [[Reviparin]], [[Tinzaparin]])
    | list1 =
* [[Low molecular weight heparin]]
** [[Bemiparin sodium|Bemiparin]]
** [[Certoparin sodium|Certoparin]]
** [[Dalteparin sodium|Dalteparin]]
** [[Enoxaparin sodium|Enoxaparin]]
** [[Nadroparin calcium|Nadroparin]]
** [[Parnaparin sodium|Parnaparin]]
** [[Reviparin sodium|Reviparin]]
** [[Tinzaparin sodium|Tinzaparin]]
* [[Oligosaccharide]]s
** [[Fondaparinux]]
** [[Idraparinux]]<sup>§</sup>
* [[Heparinoid]]s
** [[Danaparoid]]
** [[Dermatan sulfate]]
** [[Sulodexide]]


''[[oligosaccharide]]s'' ([[Fondaparinux]], [[Idraparinux]])
    | group2 = [[Direct Xa inhibitor]]s ("xabans")
    | list2 =
* [[Apixaban]]
* [[Betrixaban]]
* [[Darexaban]]<sup>§</sup>
* [[Edoxaban]]
* [[Otamixaban]]<sup>§</sup>
* [[Rivaroxaban]]


''[[heparinoid]]'' ([[Danaparoid]], [[Sulodexide]], [[Dermatan sulfate]])
  }}


| group7 = [[Direct factor Xa inhibitor]]s
<!-- group3 omitted to preserve alternating striping -->
|  list7 = ''xabans'' ([[Apixaban]], [[Otamixaban]], [[Rivaroxaban]])


}}
  | group4 = [[Direct thrombin inhibitor|Direct thrombin (IIa) inhibitor]]s
  | list4 =
* [[Direct thrombin inhibitor#Bivalent|Bivalent]]: [[Hirudin]]
** [[Bivalirudin]]
** [[Desirudin]]
** [[Lepirudin]]
* [[Direct thrombin inhibitor#Univalent|Univalent]]: [[Argatroban]]
* [[Dabigatran]]
* [[Efegatran]]
* [[Inogatran]]<sup>§</sup>
* [[Melagatran]]<sup>‡</sup>
* [[Ximelagatran]]<sup>‡</sup>


| group6 = [[Direct thrombin inhibitor|Direct thrombin (II) inhibitor]]s
  | group5 = Other
|  list6 = ''[[Direct_thrombin_inhibitor#Bivalent|bivalent]]:'' [[Hirudin]] ([[Bivalirudin]], [[Lepirudin]], [[Desirudin]])<BR>
  | list5 =
* [[Antithrombin|Antithrombin III]]
* [[Defibrotide]]
* [[Protein C]]
** [[Drotrecogin alfa]]<sup>‡</sup>
* [[Ramatroban]]
* [[REG1<!--instantly reversible aptamer-based direct FIXa inhibitor in IIb trials -->]]


''[[Direct_thrombin_inhibitor#Univalent|univalent]]:'' [[Argatroban]] • [[Dabigatran]] • [[Melagatran]] • [[Ximelagatran]]
}}


| group3 = [[Thrombolytic drug]]s/<br />[[fibrinolytic]]s
| list3 =
* [[Plasminogen activator]]s: [[Recombinant tissue plasminogen activators|r-tPA]]
** [[Alteplase]]
** [[Reteplase]]
** [[Tenecteplase]]
** [[Desmoteplase]]<sup>†</sup>
* UPA
** [[Saruplase]]
** [[Urokinase]]
* [[Anistreplase]]
* [[Monteplase]]
* [[Streptokinase]]<sup>#</sup>
* Other [[serine endopeptidase]]s: [[Ancrod]]
* [[Brinase]]
* [[Fibrinolysin]]


| group8 = Other
  | group4 = [[Anticoagulant|Non-medicinal]]
| list8 = [[Defibrotide]] • [[Ramatroban]] • [[Antithrombin|Antithrombin III]] • [[Protein C]] ([[Drotrecogin alfa]])
| list4 =
 
* [[Citrate]]
}}
* [[Ethylenediaminetetraacetic acid|EDTA]]
 
* [[Oxalate]]
| group5 = [[Thrombolytic drug]]s/<BR>[[fibrinolytic]]s
|  list5 = ''[[plasminogen activator]]s:'' ''TPA'' ([[Tissue plasminogen activator|Alteplase]], [[Reteplase]], [[Tenecteplase]]) • ''UPA'' ([[Urokinase]], [[Saruplase]]) • [[Streptokinase]] # • [[Anistreplase]] • [[Monteplase]]
 
''other [[serine endopeptidase]]s:'' [[Ancrod]] • [[Fibrinolysin]]
 
[[Brinase]]
 
 
| group8 = [[Anticoagulant#Anticoagulants outside the body|Non-medicinal]]
| list8 = [[Citrate]] [[EDTA]] [[Oxalate]]
 
| group9 =
| list9  = ''# = [[List of World Health Organization Essential Medicines|WHO-EM]]''


| belowstyle = background: transparent; padding: 0px;
| below = {{PharmNavFootnote}}


}}<noinclude>
}}<noinclude>
 
{{collapsible option}}
[[Category:Drug templates|{{PAGENAME}}]]
[[Category:Drug templates by ATC]]
</noinclude>
</noinclude>

Latest revision as of 08:52, 10 January 2019

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