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__NOTOC__
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''.
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''.
{{Paget's disease of the breast}}
{{CMG}}; {{AE}} {{Preeti}}


{{Infobox_Disease |
{{SK}} Paget disease of the nipple; Paget disease of the breast; Paget's disease of the nipple; Mammary Paget’s Disease; Paget Disease - Breast; Paget’s Disease of the Nipple; Paget's Disease - Breast
  Name          = {{PAGENAME}} |
  Image          = Paget disease of the breast 1.jpg|
  Caption        = Paget's disease of the breast <br> <small> [http://www.peir.net Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] </small>|
  DiseasesDB    = 9500 |
  ICD10          = {{ICD10|C|50||c|50}} |
  ICD9          = {{ICD9|174}} |
  ICDO          = M8540/3 |
  OMIM          = |
  MedlinePlus    = |
  eMedicineSubj  = derm |
  eMedicineTopic = 305 |
  MeshID        = D010144 |
}}
{{SI}}
{{CMG}}


{{Editor Help}}
==[[Paget's disease of the breast overview|Overview]]==
==[[Paget's disease of the breast historical perspective|Historical Perspective]]==
==[[Paget's disease of the breast classification|Classification]]==


==Overview==
==[[Paget's disease of the breast pathophysiology|Pathophysiology]]==


'''Paget's disease of the [[breast]]''', also known as '''Paget's disease of the [[nipple]]''', is a condition that outwardly may have the appearance of [[eczema]] - with skin changes involving the nipple of the breast. Because of its seemingly innocuous and surface appearance, it often presents late, but it is a condition that may be fatal.
==[[Paget's disease of the breast causes|Causes]]==


[[Extramammary Paget's disease]] (EMPD) has the same histologic features as Paget's disease of the breast but different locations.
==[[Paget's disease of the breast differential diagnosis|Differentiating Paget's disease of the breast from other Diseases]]==
==Symptoms==
Usually only affecting one nipple, The first symptom is usually an eczema-like rash. The skin of the nipple and areola may be red and inflamed. Some women have an itching or burning sensation. Fluid (discharge) may leak from the abnormal area of cells. The nipple may turn inwards (be inverted). There may or may not be a lump in the breast there may be redness, oozing and crusting, and a sore that does not heal.


==Diagnosis==
==[[Paget's disease of the breast epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Paget's disease of the breast risk factors|Risk Factors]]==


Recommended tests are a [[mammogram]] and a [[biopsy]] to confirm the diagnosis, and cytology may also be helpful.
==[[Paget's disease of the breast screening|Screening]]==


==Pathological Findings==
==[[Paget's disease of the breast natural history, complications and prognosis|Natural History, Complications and Prognosis]]==  


[http://www.peir.net Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology]


<div align="left">
==[[Paget's disease of the breast historical perspective|Historical perspective]]==
<gallery heights="175" widths="175">
==Diagnosis==
Image:Paget disease of the breast 2.jpg|Paget's disease, nipple; Crusted eroded surface, typical lesion. Always with carcinoma.
[[Paget's disease of the breast staging|Staging]] | [[Paget's disease of the breast history and symptoms|History and Symptoms]] | [[Paget's disease of the breast physical examination|Physical Examination]] | [[Paget's disease of the breast ultrasonography|Ultrasonography]] | [[Paget's disease of the breast other imaging findings|Other Imaging Findings]] | [[Paget's disease of the breast other diagnostic studies|Other Diagnostic Studies]]
</gallery>
</div>


==Treatment==
==Treatment==
Treatment usually involves some kind of [[mastectomy]] to surgically remove the tumour. [[Chemotherapy]] and/or [[radiotherapy]] may be necessary.
[[Paget's disease of the breast medical therapy|Medical Therapy]] | [[Paget's disease of the breast surgery|Surgery]] | [[Paget's disease of the breast radiation therapy|Radiation therapy]] | [[Paget's disease of the breast cost-effectiveness of therapy|Cost-Effectiveness of Therapyy]] | [[Paget's disease of the breast future or investigational therapies|Future or Investigational Therapies]]


==History==
==Case Studies==
The condition is named after Sir [[James Paget]], an English [[surgery|surgeon]] who first described it in 1874.
:[[Paget's disease of the breast case study one|Case #1]]


==External links==
==External links==
*[http://www.cancer.gov/cancertopics/factsheet/Sites-Types/pagets-breast National Cancer Institute fact sheet]
*[http://www.cancer.gov/cancertopics/factsheet/Sites-Types/pagets-breast National Cancer Institute fact sheet]
* [http://www.snopes.com/medical/disease/paget.asp Snopes]
* [http://www.mayoclinic.com/health/pagets-disease-of-the-breast/DS00771 Overview at mayoclinic.com]
* [http://etmd.medctr.ucla.edu/ETMD%2Fmd%20info%2Fphotos%2Fpaget.html Image at medctr.ucla.edu]


{{Epithelial neoplasms}}
{{Breast neoplasia}}
{{Breast neoplasia}}
{{SIB}}
[[it:Malattia di Paget del capezzolo]]
[[pl:Rak Pageta]]


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[[Category:Disease]]
[[Category:Breast cancer]]
[[Category:Breast cancer]]
[[Category:Epidermal nevi, neoplasms, cysts]]
[[Category:Epidermal nevi, neoplasms, cysts]]
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[[Category:Mature chapter]]
[[it:Malattia di Paget del capezzolo]]
[[Category:Up-To-Date]]
[[pl:Rak Pageta]]
[[Category:Oncology]]
 
[[Category:Medicine]]
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[[Category:Surgery]]

Latest revision as of 23:19, 24 February 2019

For patient information click here.

Paget's disease of the breast Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Paget's disease of the breast from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Biopsy

Ultrasonography

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Preeti Singh, M.B.B.S.[2]

Synonyms and keywords: Paget disease of the nipple; Paget disease of the breast; Paget's disease of the nipple; Mammary Paget’s Disease; Paget Disease - Breast; Paget’s Disease of the Nipple; Paget's Disease - Breast

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Paget's disease of the breast from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Historical perspective

Diagnosis

Staging | History and Symptoms | Physical Examination | Ultrasonography | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Radiation therapy | Cost-Effectiveness of Therapyy | Future or Investigational Therapies

Case Studies

Case #1

External links

Template:Breast neoplasia it:Malattia di Paget del capezzolo


Template:WikiDoc Sources