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| | __NOTOC__ |
| | [[Image:164px-Coarct_3d.gif|Left|thumb|250px|Coarctation of aorta by CMR]] |
| '''For patient information click [[{{PAGENAME}} (patient information)|here]]''' | | '''For patient information click [[{{PAGENAME}} (patient information)|here]]''' |
| {{Infobox_Disease | | | {{Aortic coarctation}} |
| Name = {{PAGENAME}} |
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| Image = Coarctation-of-the-aorta-MRI-003.jpg|
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| Caption = |
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| DiseasesDB = 2876 |
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| ICD10 = {{ICD10|Q|25|1|q|20}} |
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| ICD9 = {{ICD9|747.10}} |
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| ICDO = |
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| OMIM = 120000 |
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| MedlinePlus = |
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| eMedicineSubj = med |
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| eMedicineTopic = 154 |
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| MeshID = D001017 |
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| }}
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| [[Image:Coarctation.png|thumb|right|Sketch showing heart with coarctation of the aorta. A: Coarctation (narrowing) of the aorta. 1:inferior caval vein, 2:right pulmonary veins, 3: right pulmonary artery, 4:superior caval vein, 5:left pulmonary artery, 6:left pulmonary veins, 7:right ventricle, 8:left ventricle, 9:pulmonary artery, 10:Aorta
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| ]]
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| {{SI}}
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| {{SI}}
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| {{CMG}}
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| '''Associate Editor-In-Chief:''' {{CZ}} | | {{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]][mailto:psingh13579@gmail.com], {{CZ}}; '''Assistant Editor(s)-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]][mailto:kfeeney@elon.edu] |
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| {{Editor Help}} | | {{SK}} coarct; coarctation of the aorta |
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| | == [[Aortic coarctation overview|Overview]] == |
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| ==[[Aortic coarctation overview | Overview]]== | | == [[Aortic coarctation historical perspective|Historical Perspective]] == |
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| ==[[Aortic coarctation history | History]]== | | == [[Aortic coarctation classification|Classification]] == |
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| ==[[Aortic coarctation epidemiology and demographics | Epidemiology and demographics]]== | | == [[Aortic coarctation pathophysiology|Pathophysiology]] == |
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| ==[[Aortic coarctation classification | Classification]]== | | == [[Aortic coarctation causes|Causes]] == |
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| ==[[Aortic coarctation anatomy | Anatomy]]== | | == [[Aortic coarctation differential diagnosis|Differentiating Aortic Coarctation from other Diseases]] == |
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| ==[[Aortic coarctation pathophysiology | Pathophysiology]]== | | == [[Aortic coarctation epidemiology and demographics|Epidemiology and Demographics]] == |
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| ==[[Aortic coarctation natural history | Natural History]]== | | == [[Aortic coarctation risk factors|Risk Factors]] == |
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| ==[[Aortic coarctation genetics | Genetics]]== | | == [[Aortic coarctation screening|Screening]] == |
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| ==[[Aortic coarctation complications | Complications]]== | | == [[Aortic coarctation natural history, complications and prognosis|Natural History, Complications and Prognosis]] == |
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| | == Diagnosis == |
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| ==[[Aortic coarctation associated conditions | Associated conditions]]==
| | [[Aortic coarctation history and symptoms|History and Symptoms]] | [[Aortic coarctation physical examination|Physical Examination]] | [[Aortic coarctation electrocardiogram|Electrocardiogram]] | [[Aortic coarctation chest x-ray|Chest X Ray]] | [[Aortic coarctation CT|CT]] | [[Aortic coarctation MRI|MRI]] | [[Aortic coarctation angiography|Angiography]] | [[Aortic coarctation echocardiography|Echocardiography]] |
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| ==Diagnosis== | | == [[Aortic coarctation treatment|Treatment]] == |
| [[Aortic coarctation symptoms | Symptoms]] | [[Aortic coarctation physical examination | Physical examination]] | |
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| ===Laboratory Findings===
| | [[Aortic coarctation medical therapy|Medical Therapy]] | [[Aortic coarctation surgery|Surgery]] | [[Aortic coarctation primary prevention|Primary Prevention]] | [[Aortic coarctation secondary prevention|Secondary Prevention]] | [[Aortic coarctation cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Aortic coarctation future or investigational therapies|Future or Investigational Therapies]] |
| ===Electrocardiogram=== | | ==Case Studies== |
| With severe coarctation, left ventricular hypertrophy [[LVH]] may be present.
| | [[Aortic coarctation case study one|Case #1]] |
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| ===Chest X Ray===
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| Irregularities or notching of the inferior margins of the posterior ribs results from collateral flow through dilated and pulsatile intercostal arteries. These collaterals appear after 6 years of age if the coarctation is significant.
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| Post-stenotic dilation of the aorta results in a classic 'reverse 3 sign' on [[x-ray]]. The characteristic bulging of the sign is caused by dilatation of the aorta due to an indrawing of the [[aorta|aortic wall]] at the site of [[cervical]] [[rib]] obstruction, with consequent post-stenotic dilation. This physiology results in the reversed '3' image for which the sign is named.<ref name="medstudy">{{cite book|last=Sabatine|first=Marc|title = Pocket Medicine|publisher=Lippincott Williams & Wilkins|date=February 15, 2000|pages=256 pages|isbn=0781716497}}</ref><ref>{{cite web|url=http://www.amazon.com/dp/007146431X/|title=General Surgery ABSITE and Board Review (Pearls of Wisdom)|author=Blecha, Matthew J.|date=August 30, 2005|publisher=McGraw-Hill|isbn=978-0071464314}}</ref><ref>{{cite web|url=http://www.amazon.com/dp/0976155273/|title=Quick Essentials: Emergency Medicine, 2nd Edition|author=Brady Pregerson|date=October 1, 2006|publisher=ED Insight Books|isbn=0976155273}}</ref>
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| Chest X-ray below showing 3 sign and arrows pointing to notching of ribs.
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| [[Image:COA_x-ray.jpg]] [[Image:COA x-ray labeled.jpg]]
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| ===Echocardiography===
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| *Useful in determining associated abnormalities.
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| *Weyman et al were able to visualize this area and make the diagnosis on 2D echo in 16/18 patients.
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| *Confirmation by cardiac catheterization is unnecessary. Only done when the diagnosis is unclear, which is rare. It is mandatory in the infant to determine preoperative anatomy.
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| <googlevideo>-1958798054061108175&hl=en</googlevideo>
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| <googlevideo>-5952201527214554387&hl=en</googlevideo>
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| ===Angiography===
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| <youtube v=yvwCL3D8MFM />
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| ===MRI===
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| Magnetic resonance imaging (MRI) can define the location and severity of a coarctation. MRI can also detect associated cardiac abnormalities and is used for serial follow-up after surgical repair or balloon angioplasty. MR angiography has almost completely replaced invasive catheter based techniques for evaluating re coarctation. In adults with untreated coarctation blood often reaches the lower body through collaterals, eg. internal thoracic arteries via. the subclavian arteries. Those can be seen on MR or [[angiography]].
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| [[Image:Coarctation and PDA.png|center|thumb|250px|Schematic drawing of alternative locations of a coarctation of the aorta, relative to the ductus arteriosus. A: ductal coarctation, B: preductal coarctation, C: postductal coarctation. 1: Aorta ascendens, 2: Arteria pulmonalis, 3: Ductus arteriosus, 4: Aorta descendens, 5: Trunchus brachiocephalicus, 6: Arteria carotis communis sinister, 7: Arteria subclavia sinister]]
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| <div align="left">
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| <gallery heights="225" widths="225">
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| Image:Coarctation-of-the-aorta-MRI-003.jpg|[Courtesy of RadsWiki and copylefted]
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| Image:Coarctation-of-the-aorta-MRI-002.jpg|[Courtesy of RadsWiki and copylefted]
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| Image:Aortic coarctation MRI 001.jpg|<br> <small> [http://www.peir.net Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] </small>
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| </gallery>
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| </div>
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| ===CT===
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| <small> CT images shown below are courtesy of Cafer Zorkun and copylefted </small>
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| <div align="left">
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| <gallery heights="150" widths="150">
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| Image:Coarctation-of-the-aorta-CT-002.jpg|Aortic Coarctation
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| Image:Coarctation-of-the-aorta-CT-003.jpg|Aortic Coarctation
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| Image:Coarctation-of-the-aorta-CT-004.jpg|Aortic Coarctation
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| Image:Coarctation-of-the-aorta-CT-005.jpg|Aortic Coarctation
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| </gallery>
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| </div>
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| ==Therapy==
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| Therapy is conservative if the patient is asymptomatic. If symptoms or [[hypertension]] are present, treatment for coarctation may be surgical or catheter based. The treatment choice depends on the patients age, the location of the coarctation and other associated anomalies. Recoartctaion after previous surgery is treated percutaneously with either balloon dilation and/or stenting.
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| == References ==
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| {{reflist}}
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| ==External links==
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| * A case of coarctation of the aorta was published in the [[New England Journal of Medicine]] in 2007 showing chest X-Rays and MRT Images.<ref>{{cite journal | author = Quiros-Lopez R, Garcia-Alegria J | title = A medical mystery -- high blood pressure | journal = N Engl J Med | volume = 356 | issue = 25 | pages = 2630 | year = 2007 | id = PMID 17582073}}</ref>
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| * [http://heart.seattlechildrens.org/conditions_treated/coarctation_of_the_aorta.asp Aortic Coarctation information] from Seattle Children's Hospital Heart Center
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| * [http://www.childrenscentralcal.org/content.asp?id=939&parent=1&groupid=G0044 Overview and diagram at childrenscentralcal.org]
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| * [http://www.kumc.edu/instruction/medicine/pedcard/cardiology/pedcardio/coarctationdiagram.gif Diagram at kumc.edu]
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| * [http://www.med.umich.edu/cvc/mchc/parcoa.htm Overview and diagram at umich.edu]
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| * [http://www.nlm.nih.gov/medlineplus/ency/article/000191.htm]
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| {{Congenital malformations and deformations of circulatory system}}
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| {{SIB}}
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| [[Category:Cardiology]]
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| [[Category:Pediatrics]]
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| [[Category:DiseaseState]]
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| {{Link FA|nn}}
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| [[de:Aortenisthmusstenose]]
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| [[fr:Coarctation de l'aorte]] | | [[fr:Coarctation de l'aorte]] |
| [[it:Coartazione dell'aorta]]
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| [[no:Koarktasjon av aorta]]
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| [[nn:Koarktasjon]]
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| [[pl:Koarktacja aorty]] | | [[pl:Koarktacja aorty]] |
| [[sr:Коарктација аорте]]
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| [[tr:Aort koarktasyonu]] | | [[tr:Aort koarktasyonu]] |
| [[uk:Коарктація аорти]]
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| [[ro:Coarctaţia de Aortă]]
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| {{WikiDoc Help Menu}} | | {{WikiDoc Help Menu}} |
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| {{WikiDoc Sources}} | | {{WikiDoc Sources}} |
| | [[CME Category::Cardiology]] |
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| | [[Category:Cardiology]] |
| | [[Category:Pediatrics]] |
| | [[Category:Disease]] |
| | [[Category:Congenital heart disease]] |
