Transposition of the great vessels causes: Difference between revisions
New page: {{Template:Transposition of the great vessels}} {{CMG}} ==Causes== The cause of most congenital heart defects is unknown. Factors in the mother that may increase the risk of this conditi... |
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{{Template:Transposition of the great vessels}} | {{Template:Transposition of the great vessels}} | ||
{{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [mailto:psingh13579@gmail.com]; {{CZ}}; [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu];[[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu] | |||
==Overview== | |||
The causes for transposition of the great arteries is unknown and is presumed to be multifactorial. The embryology likely involves abnormal persistence of the subaortic conus with resorption or underdevelopment of the subpulmonary conus (infundibulum). This abnormality aligns the aorta anterior and superior with the right ventricle during development. | |||
==Causes== | ==Causes== | ||
*The etiology for transposition of the great arteries is unknown and is presumed to be multifactorial.<ref name="Praagh2010">{{cite journal|last1=Praagh|first1=Richard Van|title=Normally and Abnormally Related Great Arteries|journal=World Journal for Pediatric and Congenital Heart Surgery|volume=1|issue=3|year=2010|pages=364–385|issn=2150-1351|doi=10.1177/2150135110380239}}</ref> | |||
* | *The embryology likely involves abnormal persistence of the subaortic conus with resorption or underdevelopment of the infundibulum. This abnormality aligns the [[aorta]] anterior and superior with the [[right ventricle]] during development. | ||
*Generally, TGA is not known to be associated with any specific single gene defect, but some studies have shown possible genetic association in some cases of TGA, involving deletions of chromosome 22q11. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category: | [[Category:Disease]] | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category:Congenital heart disease]] | [[Category:Congenital heart disease]] | ||
Latest revision as of 17:01, 25 February 2020
Transposition of the great vessels Microchapters |
Classification |
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Differentiating Transposition of the great vessels from other Diseases |
Diagnosis |
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Surgery |
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Transposition of the great vessels causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4];Kristin Feeney, B.S. [5]
Overview
The causes for transposition of the great arteries is unknown and is presumed to be multifactorial. The embryology likely involves abnormal persistence of the subaortic conus with resorption or underdevelopment of the subpulmonary conus (infundibulum). This abnormality aligns the aorta anterior and superior with the right ventricle during development.
Causes
- The etiology for transposition of the great arteries is unknown and is presumed to be multifactorial.[1]
- The embryology likely involves abnormal persistence of the subaortic conus with resorption or underdevelopment of the infundibulum. This abnormality aligns the aorta anterior and superior with the right ventricle during development.
- Generally, TGA is not known to be associated with any specific single gene defect, but some studies have shown possible genetic association in some cases of TGA, involving deletions of chromosome 22q11.
References
- ↑ Praagh, Richard Van (2010). "Normally and Abnormally Related Great Arteries". World Journal for Pediatric and Congenital Heart Surgery. 1 (3): 364–385. doi:10.1177/2150135110380239. ISSN 2150-1351.