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{{Search infobox}}
__NOTOC__
{{CMG}}


{{SK}} painful swallowing
'''For patient information on this topic, click [[odynophagia (patient information)|here]].'''
{{Odynophagia}}
{{CMG}}; {{AE}} {{SKA}}


==Overview==
{{SK}} Painful swallowing, Pain during swallowing, Odenophagia, Odinophagia, Odenophagia.
'''Odynophagia''' is defined as painful swallowing.


== Causes==
==[[Odynophagia overview|Overview]]==
===Causes in Alphabetical Order. <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref> <ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>===
==[[Odynophagia historical perspective|Historical Perspective]]==
==[[Odynophagia pathophysiology|Pathophysiology]]==
==[[Odynophagia causes|Causes]]==
==[[Odynophagia differential diagnosis|Differentiating Odynophagia from other Conditions]]==
==[[Odynophagia epidemiology and demographics|Epidemiology and Demographics]]==
==[[Odynophagia risk factors|Risk Factors]]==
==[[Odynophagia natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==Diagnosis==
[[Odynophagia history and symptoms|History and Symptoms]] | [[Odynophagia physical examination|Physical Examination]] | [[Odynophagia laboratory findings|Laboratory Findings]] | [[Odynophagia electrocardiogram|Electrocardiogram]] | [[Odynophagia chest x ray|Chest X Ray]] | [[Odynophagia CT|CT]] | [[Odynophagia MRI|MRI]] | [[Odynophagia echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Odynophagia other imaging findings|Other Imaging Findings]] | [[Odynophagia other diagnostic studies|Other Diagnostic Studies]]


* [[Abscess]]es
==Treatment==
* [[Achalasia]]
* [[Aerophagia]]
* [[Agranulocytosis]]
* [[Alcoholism]]
* Allergic swelling
* [[Amyloidosis]]
* [[Amyotrophic Lateral Sclerosis]] (ALS)
* Angina tonsillaris
* Anxiety disorders
* [[Aortic aneurysm]]
* Aspiration of foreign body
* [[Barret's Syndrome]]
* [[Behcet's Syndrome]]
* [[Botulism]]
* [[Brainstem stroke]]
* [[Bronchial carcinoma]]
* [[Bulbar palsy]]
* [[Candidiasis]]
* Cascade stomach
* Central hypoglossal nerve paralysis
* Central vagal nucleus lesion
* [[Cerebrovascular accident]] ([[CVA]])
* [[Chagas Disease]]
* Chemical burns
* [[CREST syndrome]] ('''c'''alcinosis '''r'''aynaud's phenomenon '''e'''sophagus '''s'''clerodactyly '''t'''elangiectasias)
* [[Cytomegalovirus]] ([[CMV]])
* [[Dermatomyositis]]
* [[Diabetic neuropathy]]
* [[Diphtheria]]
* [[Diverticulum]]
* [[Left Atrial Enlargement|Enlarged left atrium]]
* [[Esophageal cancer]]
* Esophageal [[Crohn's disease]]
* [[Esophageal diverticulum]]
* Esophageal moniliasis
* Esophageal [[sarcoidosis]]
* [[Esophageal spasm]]
* Esophageal trauma
* [[Esophagotracheal fistula]]
* Extreme spinal curvature
* Fibrosis
* Food bolus
* Gastric tumors
* [[Gastritis]]
* [[Gastroparesis]]
* [[Global hystericus]]
* Globus syndrome
* [[Goiter]]
* [[Graft versus host reaction]]
* [[Guillain-Barre Syndrome]]
* [[Herpangina]]
* [[Herpes simplex virus]] ([[HSV]])
* [[Hiatal hernia]]
* [[Huntington's chorea]]
* [[Hyperthyroidism]]
* [[Hypokalemia]]
* [[Hypothyroidism]]
* Idiopathic [[human immunodeficiency virus]][[HIV]] ulcers
* Impaired sensitivity in the larynx
* Intramural pseudodiverticulosis
* [[Laryngeal cancer]]
* Lateral funiculus angina
* [[Leiomyoma]]
* [[Ludwig's angina]]
* Lymph granulomatosis
* [[Lymphadenopathy]]
* Medication-induced [[esophagitis]]
* [[Mononucleosis]]
* [[Multiple Sclerosis]]
* [[Mumps]]
* [[Myasthenia Gravis]]
* Neoplastic (external compression)
* [[Nutcracker esophagus]]
* Oral [[candidiasis]]
* Osteophytes
* Palatoplegia after damage to the vagal nerve or the accessory nerve
* [[Paraneoplastic syndrome]]
* [[Parkinson's Disease]]
* Peptic stenosis
* [[Peripheral neuropathy]]
* Peripheral tongue paralysis with lesions of the hypoglossal nerve
* [[Pharyngitis]]
* Pleural and pericardial causes
* [[Plummer-Vinson Syndrome]]
* [[Poliomyelitis]]
* [[Polyradiculitis]]
* [[Pseudoachalasia]]
* [[Pseudobulbar paralysis]]
* [[Pyloric stenosis]]
* [[Rabies]]
* [[Radiation esophagitis]]
* [[Reflux esophagitis]]
* [[Rheumatoid Arthritis]]
* [[Scarlet Fever]]
* [[Schatzki ring]]
* [[Scleroderma]]
* [[Stevens-Johnson Syndrome]]
* [[Stomatitis]]
* [[Syringobulbia]]
* [[Systemic Lupus Erythematosus]]
* [[Tetanus]]
* Tonsillar abscess
* [[Typhoid fever]] angina
* Vascular abnormality
* [[Vincent's angina]]
* [[Zenker's Diverticulum]]


== Diagnosis ==
[[Odynophagia medical therapy|Medical Therapy]] | [[Odynophagia surgery|Surgery]] | [[Odynophagia primary prevention|Primary Prevention]] | [[Odynophagia secondary prevention|Secondary Prevention]] | [[Odynophagia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Odynophagia future or investigational therapies|Future or Investigational Therapies]]
 
=== History and Symptoms ===
* Onset
* Severity
* Duration
* Dysphagia with liquids versus solids
* Psychiatric history
* Prior episodes
* Substance exposure
* History of neck and head problems
 
=== Laboratory Findings ===
 
==== Electrolyte and Biomarker Studies ====
* Creatinine phosphokinase (CPK) can be used to rule out cardiac ischemia as a cause.
 
=== Electrocardiogram ===
Can be used to assess for left atrial enlargement.
 
=== Chest X Ray ===
Can used to rule out lung cancer and other mass lesions as well as left atrial enlargement.
 
=== MRI and CT ===
* MRI of brain can be used to exclude CVA and mass lesions of the head and neck.
 
=== Echocardiography or Ultrasound ===
Can be used to rule out an aneurysm or left atrial enlargement as a cause.
 
=== Other Diagnostic Studies ===
* [[Esophagogastroduodenoscopy]] (OGD)
* [[Biopsy]]
* [[Barium swallow]]
* [[Electromyogram]] ([[EMG]])
* Nerve conduction tests
* Esophageal manometry
 
== Treatment ==
* Endoscopy (acute and chronic mechanical obstructions)
* Speech therapy (ALS and stroke patients)
 
== Pharmacotherapy ==
* Proton pump inhibitors or promotility agents, weight loss, avoidance of offending foods (gastroesophageal reflux disease)
* Anticholinergics (ALS, stroke, lower esophageal spasms)
* Muscarinic agents (myasthenia gravis)
* Glucocorticoids (myasthenia gravis and polymyositis)
* Antispasmodics, botulinum toxin injection (lower esophageal spasm)
 
== Surgery and Device Based Therapy ==
* Thoracic surgery, possible balloon dilation (chronic mechanical obstruction)
 
== References ==
{{Reflist}}
 
{{SIB}}


==Case Studies==
[[Odynophagia case study one|Case #1]]


[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:Musculoskeletal Disease]]
[[Category:Musculoskeletal Disease]]
[[Category:Symptoms]]
[[Category:Signs and symptoms]]
[[Category:Signs and symptoms]]


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Latest revision as of 16:20, 27 February 2018


For patient information on this topic, click here.

Odynophagia Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Odynophagia from other Conditions

Epidemiology and Demographics

Screening

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]

Synonyms and keywords: Painful swallowing, Pain during swallowing, Odenophagia, Odinophagia, Odenophagia.

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Odynophagia from other Conditions

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1


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