Chlortetracycline: Difference between revisions
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|IUPAC_name = (2''Z'',4''S'',4''aS'',5''aS'',6''S'',12''aS'')-2-(amino-hydroxy-<br>methylidene)-7-chloro-4-dimethylamino-6,10,11,12a-<br>tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-<br>1,3,12-trione | |IUPAC_name = (2''Z'',4''S'',4''aS'',5''aS'',6''S'',12''aS'')-2-(amino-hydroxy-<br>methylidene)-7-chloro-4-dimethylamino-6,10,11,12a-<br>tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-<br>1,3,12-trione | ||
| image=Chlortetracycline. | | image=Chlortetracycline Wiki Str.png | ||
| CAS_number=57-62-5 | | CAS_number=57-62-5 | ||
| ATC_prefix=D06 | | ATC_prefix=D06 | ||
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| routes_of_administration= Oral, [[Intravenous therapy|IV]], topical | | routes_of_administration= Oral, [[Intravenous therapy|IV]], topical | ||
}} | }} | ||
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{{SI}} | {{SI}} | ||
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== Overview == | |||
'''Chlortetracycline''' (trade name '''Aureomycin®''', [[Lederle]]) is a [[Tetracycline antibiotics|tetracycline]] [[antibiotic]], and was the first tetracycline to be discovered. It was discovered in [[1945]] by Dr [[Benjamin Duggar]] in a soil sample from [[Sanborn Field]] at the [[University of Missouri]], yielding an [[actinomycete]], ''Streptomyces aureofaciens'' (hence the name Aureomycin). In [[veterinary medicine]], it is commonly used to treat [[conjunctivitis]] in [[Felines|cats]].<ref name="Merck">{{cite book | title=Merck Veterinary Manual | url=http://merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/30200.htm }}</ref> | '''Chlortetracycline''' (trade name '''Aureomycin®''', [[Lederle]]) is a [[Tetracycline antibiotics|tetracycline]] [[antibiotic]], and was the first tetracycline to be discovered. It was discovered in [[1945]] by Dr [[Benjamin Duggar]] in a soil sample from [[Sanborn Field]] at the [[University of Missouri]], yielding an [[actinomycete]], ''Streptomyces aureofaciens'' (hence the name Aureomycin). In [[veterinary medicine]], it is commonly used to treat [[conjunctivitis]] in [[Felines|cats]].<ref name="Merck">{{cite book | title=Merck Veterinary Manual | url=http://merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/30200.htm }}</ref> | ||
==References== | ==References== | ||
<div class="references-small"> | <div class="references-small"> | ||
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{{TetracyclineAntiBiotics}} | {{TetracyclineAntiBiotics}} | ||
[[Category:Drug]] | |||
[[Category:Tetracycline antibiotics]] | [[Category:Tetracycline antibiotics]] | ||
Latest revision as of 14:19, 9 April 2015
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| Clinical data | |
|---|---|
| Routes of administration | Oral, IV, topical |
| ATC code | |
| Pharmacokinetic data | |
| Bioavailability | 30% |
| Protein binding | 50 to 55% |
| Metabolism | Hepatic (75%) |
| Elimination half-life | 5.6 to 9 hours |
| Excretion | Renal and biliary |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C22H23ClN2O8 |
| Molar mass | 478.879 g/mol |
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WikiDoc Resources for Chlortetracycline |
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Cochrane Collaboration on Chlortetracycline |
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Ongoing Trials on Chlortetracycline at Clinical Trials.gov Trial results on Chlortetracycline Clinical Trials on Chlortetracycline at Google
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US National Guidelines Clearinghouse on Chlortetracycline NICE Guidance on Chlortetracycline
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Chlortetracycline (trade name Aureomycin®, Lederle) is a tetracycline antibiotic, and was the first tetracycline to be discovered. It was discovered in 1945 by Dr Benjamin Duggar in a soil sample from Sanborn Field at the University of Missouri, yielding an actinomycete, Streptomyces aureofaciens (hence the name Aureomycin). In veterinary medicine, it is commonly used to treat conjunctivitis in cats.[1]
References
de:Chlortetracyclin sv:Aureomycin th:คลอเตตร้าซัยคลิน uk:Хлортетрациклін
- Pages with script errors
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Chemical articles with unknown parameter in Infobox drug
- Articles without EBI source
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- Drugs with no legal status
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- Drug
- Tetracycline antibiotics