Cutaneous abscess secondary prevention: Difference between revisions
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To prevent recurrent infections due to ''[[Staphylococcus aureus]]'', consider the following measures: | |||
*Topical [[mupirocin]] applied to the nares.<ref name="pmid18843708">{{cite journal |author=van Rijen M, Bonten M, Wenzel R, Kluytmans J |title=Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers |journal=Cochrane Database Syst Rev |volume= |issue=4 |pages=CD006216 |year=2008 |pmid=18843708 |doi=10.1002/14651858.CD006216.pub2 |url=}}</ref> In this [[randomized controlled trial]], patients used nasal mupirocin twice daily 5 days a month for 1 year.<ref name=Raz1996>{{cite journal | author = Raz R, Miron D, Colodner R, Staler Z, Samara Z, Keness Y | title = A 1-year trial of nasal mupirocin in the prevention of recurrent staphylococcal nasal colonization and skin infection. | journal = Arch Intern Med | volume = 156 | issue = 10 | pages = 1109-12 | year = 1996 | id = PMID 8638999}}</ref> The does is about 1 centimeter of ointment on a swab applied to each nares.<ref name="pmid10348762">{{cite journal |author=Harbarth S, Dharan S, Liassine N, Herrault P, Auckenthaler R, Pittet D |title=Randomized, placebo-controlled, double-blind trial to evaluate the efficacy of mupirocin for eradicating carriage of methicillin-resistant Staphylococcus aureus |journal=Antimicrob. Agents Chemother. |volume=43 |issue=6 |pages=1412–6 |year=1999 |month=June |pmid=10348762 |pmc=89288 |doi= |url=http://aac.asm.org/cgi/pmidlookup?view=long&pmid=10348762 |issn=}}</ref> | |||
*[[Chlorhexidine]] baths,<ref name=Watanakunakorn>{{cite journal | author = Watanakunakorn C, Axelson C, Bota B, Stahl C | title = Mupirocin ointment with and without chlorhexidine baths in the eradication of Staphylococcus aureus nasal carriage in nursing home residents. | journal = Am J Infect Control | volume = 23 | issue = 5 | pages = 306-9 | year = 1995 | id = PMID 8585642}}</ref> in a [[randomized controlled trial]], nasal recolonization with S. aureus occurred at 12 weeks in 24% of nursing home residents receiving mupirocin ointment alone (6/25) and in 15% of residents receiving mupirocin ointment plus chlorhexidine baths daily for the first three days of mupirocin treatment (4/27). Although these results did not reach [[statistical significance]], the baths are easy to do. | |||
==References== | ==References== | ||
Latest revision as of 14:11, 27 March 2017
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To prevent recurrent infections due to Staphylococcus aureus, consider the following measures:
- Topical mupirocin applied to the nares.[1] In this randomized controlled trial, patients used nasal mupirocin twice daily 5 days a month for 1 year.[2] The does is about 1 centimeter of ointment on a swab applied to each nares.[3]
- Chlorhexidine baths,[4] in a randomized controlled trial, nasal recolonization with S. aureus occurred at 12 weeks in 24% of nursing home residents receiving mupirocin ointment alone (6/25) and in 15% of residents receiving mupirocin ointment plus chlorhexidine baths daily for the first three days of mupirocin treatment (4/27). Although these results did not reach statistical significance, the baths are easy to do.
References
- ↑ van Rijen M, Bonten M, Wenzel R, Kluytmans J (2008). "Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers". Cochrane Database Syst Rev (4): CD006216. doi:10.1002/14651858.CD006216.pub2. PMID 18843708.
- ↑ Raz R, Miron D, Colodner R, Staler Z, Samara Z, Keness Y (1996). "A 1-year trial of nasal mupirocin in the prevention of recurrent staphylococcal nasal colonization and skin infection". Arch Intern Med. 156 (10): 1109–12. PMID 8638999.
- ↑ Harbarth S, Dharan S, Liassine N, Herrault P, Auckenthaler R, Pittet D (1999). "Randomized, placebo-controlled, double-blind trial to evaluate the efficacy of mupirocin for eradicating carriage of methicillin-resistant Staphylococcus aureus". Antimicrob. Agents Chemother. 43 (6): 1412–6. PMC 89288. PMID 10348762. Unknown parameter
|month=ignored (help) - ↑ Watanakunakorn C, Axelson C, Bota B, Stahl C (1995). "Mupirocin ointment with and without chlorhexidine baths in the eradication of Staphylococcus aureus nasal carriage in nursing home residents". Am J Infect Control. 23 (5): 306–9. PMID 8585642.