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| | __NOTOC__ |
| {{Infobox_Disease | | | {{Infobox_Disease | |
| Name = {{PAGENAME}} | | | Name = {{PAGENAME}} | |
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| MeshID = | | | MeshID = | |
| }} | | }} |
| {{SI}} | | {{Eosinophilia}} |
| {{CMG}}; {{AOEIC}} {{LG}} | | {{CMG}}; {{AOEIC}} {{LG}}, George Leef MD |
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| == Overview ==
| | {{SK}} Eosinophil count raised (peripheral blood), hereditary eosinophilia |
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| *Eosinphilia refers to a group of idiopathic, neoplastic, infectious and allergic illnesses
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| *Eosinphilia is associated with abnormally high number of eosinphil granulocytes in the serum and/or tissue
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| * Reference range: '''0-450 ul'''
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| == Differential Diagnosis of Causes of {{PAGENAME}} == | | ==[[Eosinophilia overview|Overview]]== |
| ===By Organ System===
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| {|height:100px" border="1"
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| |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
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| |style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Endomyocardial fibrosis]], [[Cholesterol embolism]],
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| [[Loeffler endocarditis ]], [[Eosinophilic myocarditis]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Chemical / poisoning'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Dermatologic'''
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| |bgcolor="Beige"| [[Erythema multiforme]], [[Atopic dermatitis]], [[Dermatitis herpetiformis]], [[fasciitis|Eosinophilic fasciitis]], [[folliculitis|Eosinophilic pustular folliculitis]], [[Pemphigus vulgaris]], [[Psoriasis]], [[Systemic lupus erythematosus]], [[Scabies|Sarcoptes scabiei]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Drug Side Effect'''
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| |bgcolor="Beige"| [[Sulphonamides]], [[Allopurinol]], [[Amitriptyline]], [[Capreomycin]], [[Caspofungin]], [[Chlorpropamide]], [[Clomipramine]], [[Daptomycin]], [[Desipramine]], [[Dothiepin]], [[Doxycycline]], [[Enfuvirtide]], [[Etravirine]], [[Gold salts]], [[Granulocyte-macrophage colony stimulating factor]], [[Hydralazine]], [[Imipramine]], [[Interleukin 2]], [[Micafungin]], [[Minocycline]], [[Nalidixic acid]], [[Nitrofurantoin]], [[Nortriptyline]], [[Olanzapine]], [[Oxytetracycline]], [[Pentostatin]], [[Procarbazine]], [[Smoking|Tobacco smoking]], [[Tryptophan]], [[Vancomycin]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Ear Nose Throat'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Endocrine'''
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| |bgcolor="Beige"| [[Adrenal cortex insufficiency]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Environmental'''
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| |bgcolor="Beige"| An allergic reaction to an environmental antigen
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Gastroenterologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Genetic'''
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| |bgcolor="Beige"| [[Autoimmune lymphoproliferative syndrome|Autoimmune lymphoproliferative syndrome type 1]], [[Autoimmune lymphoproliferative syndrome|Autoimmune lymphoproliferative syndrome type 2]], [[Familial eosinophilia]], [[Kostmann disease]], [[Omenn syndrome]], [[Wiskott-Aldrich syndrome]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Hematologic'''
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| |bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Chronic myeloid leukaemia]], [[Hodgkin lymphoma]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Iatrogenic'''
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| |bgcolor="Beige"| [[Radiotherapy]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Infectious Disease'''
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| |bgcolor="Beige"| [[Acanthocheilonemiasis]], [[Alveolar hydatid disease]], [[Ancylostoma caninum]], [[Ancylostoma duodenale]], [[Angiostrongyliasis]], [[Anisakiasis]], [[Ascariasis]], [[Capillaria]], [[Clonorchiasis]], [[Coccidioidomycosis]], [[Dicrocoelium dendriticum fluke]], [[Dracunculiasis]], [[Echinococcus granulosus]], [[Fasciola hepatica]], [[Gnathostomiasis]], [[Heterophyiasis]], [[Lepromatous leprosy]], [[Loa loa filariasis]], [[Lymphatic filariasis]], [[Mansonelliasis]], [[Metagonimiasis]], [[Mycobacterium tuberculosis]], [[Onchocerciasis]], [[Opisthorchiasis]], [[Paragonimiasis]], [[Schistosoma haematobium]], [[Schistosoma mansoni]], [[Strongyloidiasis]], [[Toxocariasis]], [[Trichinella spiralis]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Musculoskeletal / Ortho'''
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| |bgcolor="Beige"| [[Polyarteritis nodosa]], [[Polymyositis]], [[Rheumatoid disease]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Neurologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Nutritional / Metabolic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Obstetric/Gynecologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue" | |
| | '''Oncologic'''
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| |bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Chronic myeloid leukaemia]], [[Hodgkin lymphoma]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Opthalmologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Overdose / Toxicity'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Psychiatric'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Pulmonary'''
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| |bgcolor="Beige"| [[Simple pulmonary eosinophilia]], [[Visceral larva migrans]], [[Allergic bronchopulmonary aspergillosis]], [[Extrinsic allergic alveolitis]], [[Tropical pulmonary eosinophilia]], [[Churg-Strauss syndrome]], [[Bronchial asthma]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Renal / Electrolyte'''
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| |bgcolor="Beige"| [[Interstitial nephritis]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Rheum / Immune / Allergy'''
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| |bgcolor="Beige"| [[Eosinophilia-myalgia syndrome]]
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Sexual'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Trauma'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Urologic'''
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| |bgcolor="Beige"| No underlying causes
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| |-
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| |-bgcolor="LightSteelBlue"
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| | '''Miscellaneous'''
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| |bgcolor="Beige"| [[Angiolymphoid hyperplasia with eosinophilia]], [[cellulitis|Eosinophilic cellulitis]], [[Hypereosinophilic syndrome]], [[Kimura disease]]
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| |-
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| |}
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|
| ===In alphabetical order <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:127-128 ISBN 1591032016 | | ==[[Eosinophilia historical perspective|Historical Perspective]]== |
| </ref>===
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| *[[Acanthocheilonemiasis]]
| | ==[[Eosinophilia pathophysiology|Pathophysiology]]== |
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| *[[Acute lymphoblastic leukemia ]]
| | ==[[Eosinophilia causes|Causes]]== |
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| *[[Acute eosinophilic leukemia ]]
| | ==[[Eosinophilia differential diagnosis|Differentiating Eosinophilia from other Diseases]]== |
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| *[[Chronic eosinophilic leukemia ]]
| | ==[[Eosinophilia epidemiology and demographics|Epidemiology and Demographics]]== |
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| *[[Addisons disease ]]
| | ==[[Eosinophilia risk factors|Risk Factors]]== |
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| *[[Adrenocortical insufficiency]]
| | ==[[Eosinophilia natural history, complications and prognosis|Natural History, Complications and Prognosis]]== |
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| *[[Aggressive systemic mastocytosis ]]
| | ==Diagnosis== |
| | [[Eosinophilia history and symptoms|History and Symptoms]] | [[Eosinophilia physical examination|Physical Examination]] | [[Eosinophilia laboratory findings|Laboratory Findings]] | [[Eosinophilia CT|CT]] | [[Eosinophilia other diagnostic studies|Other Diagnostic Studies]] |
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| *[[Aldesleukin ]]
| | ==Treatment== |
| | [[Eosinophilia medical therapy|Medical Therapy]] | [[Eosinophilia surgery|Surgery]] | [[Eosinophilia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Eosinophilia future or investigational therapies|Future or Investigational Therapies]] |
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| *[[Allergic bronchopulmonary aspergillosis ]]
| | ==Case Studies== |
| | | [[Eosinophilia case study one|Case #1]] |
| *[[Allergic Rhinitis]]
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| *[[Allopurinol ]]
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| *[[Alveolar hydatid disease ]]
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| *[[Amebiasis ]]
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| *[[Amikacin Sulfate ]]
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| *[[Amitriptyline ]]
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| *[[Ancylostoma caninum ]]
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| *[[Ancylostoma duodenale ]]
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| *[[Angiolymphoid hyperplasia with eosinophilia ]]
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| *[[Angiostrongyliasis ]]
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| *[[Anisakiasis ]]
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| *[[Ascariasis ]]
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| *[[Atopic dermatitis ]]
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| *[[Autoimmune lymphoproliferative syndrome type 1 ]]
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| *[[Autoimmune lymphoproliferative syndrome type 2 ]]
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| *[[Brain Tumors ]]
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| *[[Bronchial asthma ]]
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| *[[Brucellosis ]]
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| *[[Capastat Sulfate ]]
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| *[[Capillaria ]]
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| *[[Capreomycin ]]
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| *[[Caspofungin ]]
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| *[[Cat-scratch fever ]]
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| *[[Cefotaxime Sodium ]]
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| *[[Cefoxitin Sodium ]]
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| *[[Ceftazidime ]]
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| *[[Cefuroxime ]]
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| *[[Chlamydial pneumonia of infancy ]]
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| *[[Chlorpropamide ]]
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| *[[Cholesterol embolism ]]
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| *[[Chromosome 21 partial deletion ]]
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| *[[Chronic active hepatitis ]]
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| *[[Chronic eosinophilic pneumonia ]]
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| *[[Chronic myeloid leukaemia ]]
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| *[[Churg-Strauss syndrome ]]
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| *[[Cirrhosis ]]
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| *[[Cirrhosis of liver ]]
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| *[[Clomipramine]]
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| *[[Clonorchiasis ]]
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| *[[Coccidioidomycosis ]]
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| *[[CRF not on renal replacement therapy ]]
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| *[[Daptomycin ]]
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| *[[Dermatitis herpetiformis ]]
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| *[[Dermatomyositis ]]
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| *[[Desipramine ]]
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| *[[Dicrocoelium dendriticum fluke ]]
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| *[[Diffuse proliferative glomerular nephritis ]]
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| *[[Dothiepin ]]
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| *[[Doxycycline ]]
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| *[[Dracunculiasis ]]
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| *[[Dressler's syndrome ]]
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| *[[Duhring's disease ]]
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| *[[Echinococcus granulosus ]]
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| *[[Eczema ]]
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| *[[Endomyocardial fibrosis ]]
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| *[[Enfuvirtide ]]
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| *[[Eosinophilia – myalgia syndrome ]]
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| *[[Eosinophilic cellulitis ]]
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| *[[Eosinophilic cystitis ]]
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| *[[Eosinophilic fasciitis ]]
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| *[[Eosinophilic gastroenteritis ]]
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| *[[Eosinophilic myocarditis]]
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| *[[Eosinophilic panniculitis ]]
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| *[[Eosinophilic pustular folliculitis ]]
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| *[[Episodic angioedema with eosinophilia ]]
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| *[[Erythema multiforme ]]
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| *[[Etravirine ]]
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| *[[Exfoliative dermatitis ]]
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| *[[Extrinsic allergic alveolitis ]]
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| *[[Familial eosinophilia ]]
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| *[[Familial eosinophilia]]
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| *[[Familial reticuloendotheliosis with eosinophilia]]
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| *[[Fasciola hepatica ]]
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| *[[Gnathostomiasis ]]
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| *[[Gold salts ]]
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| *[[Graft versus host immunologic reactions ]]
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| *[[Granulocyte-macrophage colony stimulating factor ]]
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| *[[Hemodialysis ]]
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| *[[Heterophyiasis ]]
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| *[[Histiositosis with Cutaneous involvement ]]
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| *[[Hodgkin lymphoma ]]
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| *[[Hydralazine ]]
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| *[[Hypereosinophilic syndrome ]]
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| *[[Hyper-IgE syndrome ]]
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| *[[Idiopathic eosinophilic chronic pneumopathy ]]
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| *[[Idiopathic eosinophilic synovitis ]]
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| *[[IgA deficiency ]]
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| *[[Imipramine ]]
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| *[[Immunoblastic lymphadenopathy ]]
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| *[[Infectious lymphocytosis ]]
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| *[[Infectious mononucleosis ]]
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| *[[Inflammatory Bowel Disease ]]
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| *[[Interleukin 2 ]]
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| *[[Interstitial nephritis ]]
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| *[[Kimura disease ]]
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| *[[Kostmann syndrome]]
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| *[[Lepromatous leprosy ]]
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| *[[Loa loa filariasis ]]
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| *[[Loeffler endocarditis ]]
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| *[[L-Tryptophan use ]]
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| *[[Lymphatic filariasis ]]
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| *[[Lyphocin maolate ]]
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| *[[Magrassi- Leonardi syndrome ]]
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| *[[Malaria ]]
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| *[[Mansonelliasis ]]
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| *[[Metagonimiasis ]]
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| *[[Micafungin ]]
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| *[[Milk protein allergy ]]
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| *[[Minocycline ]]
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| *[[Mycobacterium tuberculosis ]]
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| *[[Nalidixic acid ]]
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| *[[Nitrofurantoin ]]
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| *[[Nortriptyline ]]
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| *[[Occupational lung diseases ]]
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| *[[Olanzapine ]]
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| *[[Omenn syndrome ]]
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| *[[Onchocerciasis ]]
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| *[[Opisthorchiasis ]]
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| *[[Oxytetracycline]]
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| *[[Paragonimiasis ]]
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| *[[Pemphigus vulgaris ]]
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| *[[Pentostatin ]]
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| *[[Peritoneal dialysis ]]
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| *[[Pneumocystis jirovecii infection ]]
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| *[[Polyarteritis nodosa ]]
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| *[[Polymyositis ]]
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| *[[Procarbazine ]]
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| *[[Progressive systemic sclerosis (scleroderma) ]]
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| *[[Psoriasis ]]
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| *[[RA ]]
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| *[[Radiation therapy ]]
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| *[[Radiotherapy]]
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| *[[Renal cell carcinoma]]
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| *[[Sarcoidosis ]]
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| *[[Sarcomas and carcinomas of Ovary/ Cervix Pancreas Lung, colon ]]
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| *[[Sarcoptes scabiei ]]
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| *[[Scarlet fever ]]
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| *[[Schistosoma haematobium ]]
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| *[[Schistosoma mansoni ]]
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| *[[Severe congenital Neutropenia ]]
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| *[[Shulman’s syndrome ]]
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| *[[Simple pulmonary eosinophilia ]]
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| *[[Sjögren's syndrome ]]
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| *[[SLE ]]
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| *[[Stevens - Johnson syndrome ]]
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| *[[Strongyloidiasis ]]
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| *[[Sulphonamides ]]
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| *[[Systemic lupus erythematosus ]]
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| *[[TAR syndrome]]
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| *[[Thrombocytopenia with absent radii]]
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| *[[Thrombotic thrombocytopenic purpura ]]
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| *[[Tobacco smoking ]]
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| *[[Toxocariasis ]]
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| *[[Trichinella spiralis ]]
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| *[[Tropical pulmonary eosinophilia ]]
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| *[[Tryptophan ]]
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| *[[Urticaria ]]
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| *[[Vancomycin Hydrochloride ]]
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| *[[Vancomycin]]
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| *[[Visceral larva migrans ]]
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| *[[Wiskott-Aldrich syndrome ]]
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| ==Related Chapters== | | ==Related Chapters== |
| Line 482: |
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| *[[Monocytosis]] | | *[[Monocytosis]] |
| *[[Lymphocytosis]] | | *[[Lymphocytosis]] |
|
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| == References ==
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| {{Reflist|2}}
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| [[Category:Laboratory Test]] | | [[Category:Laboratory Test]] |
| [[Category:Hematology]] | | [[Category:Hematology]] |
| [[Category:Infectious disease]]
| | |
| [[Category:Blood tests]] | | [[Category:Blood tests]] |
|
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