Buerger's disease natural history, complications and prognosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Buerger's disease}} | {{Buerger's disease}} | ||
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==Overview== | ==Overview== | ||
==Natural History, Complications and Prognosis== | If left untreated, 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease. Common complications of Buerger disease include [[amputation]], [[gangrene]] and loss of [[Circulatory system|circulation]] beyond the affected hand or foot. [[Smoking cessation]] leads to an 8-fold decrease in the risk for [[amputation]]. [[Amputation]] is common and more severe in patients who continue to use [[tobacco]], which often leads to vascular insufficiency. Buerger's disease is rarely immediately fatal, but rather a life shortening disease. Prognosis of Buerger's disease varies from person to person, depending on the patient's life-style and the severity of the damaged vessels. | ||
==Natural History, Complications, and Prognosis== | |||
===Natural History=== | |||
*The symptoms of Buerger disease usually develop in the third to forth decade of life, and start with symptoms such as [[pallor]] and [[ischemia]] of the extremities.<ref name="pmid14718836">{{cite journal |vauthors=Ohta T, Ishioashi H, Hosaka M, Sugimoto I |title=Clinical and social consequences of Buerger disease |journal=J. Vasc. Surg. |volume=39 |issue=1 |pages=176–80 |date=January 2004 |pmid=14718836 |doi=10.1016/j.jvs.2003.08.006 |url=}}</ref><ref name="pmid15607407">{{cite journal |vauthors=Cooper LT, Tse TS, Mikhail MA, McBane RD, Stanson AW, Ballman KV |title=Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease) |journal=J. Am. Coll. Cardiol. |volume=44 |issue=12 |pages=2410–1 |date=December 2004 |pmid=15607407 |doi=10.1016/j.jacc.2004.09.029 |url=}}</ref> | |||
*If left untreated, approximately 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease. | |||
===Complications=== | |||
*Common complications of Buerger disease include:<ref name="pmid14718836">{{cite journal |vauthors=Ohta T, Ishioashi H, Hosaka M, Sugimoto I |title=Clinical and social consequences of Buerger disease |journal=J. Vasc. Surg. |volume=39 |issue=1 |pages=176–80 |date=January 2004 |pmid=14718836 |doi=10.1016/j.jvs.2003.08.006 |url=}}</ref><ref name="pmid15607407">{{cite journal |vauthors=Cooper LT, Tse TS, Mikhail MA, McBane RD, Stanson AW, Ballman KV |title=Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease) |journal=J. Am. Coll. Cardiol. |volume=44 |issue=12 |pages=2410–1 |date=December 2004 |pmid=15607407 |doi=10.1016/j.jacc.2004.09.029 |url=}}</ref> | |||
**[[Amputation]] | |||
**[[Gangrene]] | |||
**Loss of [[Circulatory system|circulation]] beyond the affected hand or foot | |||
===Prognosis=== | ===Prognosis=== | ||
Amputation is common and more severe in patients who continue to use tobacco | *[[Smoking cessation]] leads to an 8-fold decrease in the risk for amputation.<ref name="pmid14718836">{{cite journal |vauthors=Ohta T, Ishioashi H, Hosaka M, Sugimoto I |title=Clinical and social consequences of Buerger disease |journal=J. Vasc. Surg. |volume=39 |issue=1 |pages=176–80 |date=January 2004 |pmid=14718836 |doi=10.1016/j.jvs.2003.08.006 |url=}}</ref><ref name="pmid15607407">{{cite journal |vauthors=Cooper LT, Tse TS, Mikhail MA, McBane RD, Stanson AW, Ballman KV |title=Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease) |journal=J. Am. Coll. Cardiol. |volume=44 |issue=12 |pages=2410–1 |date=December 2004 |pmid=15607407 |doi=10.1016/j.jacc.2004.09.029 |url=}}</ref> | ||
*[[Amputation]] is common and more severe in patients who continue to use [[tobacco]], which often leads to vascular insufficiency. | |||
*Buerger's disease is rarely immediately fatal, but rather a life shortening disease. | |||
*Prognosis of Buerger's disease varies from person to person, depending on: | |||
**The patient's life-style | |||
**The severity of the damaged vessels | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Cardiovascular diseases]] | |||
[[Category:Angiology]] | |||
[[Category:Cardiology]] | |||
[[Category:Rheumatology]] | |||
[[Category:Up-To-Date]] | |||
Latest revision as of 16:49, 11 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
If left untreated, 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease. Common complications of Buerger disease include amputation, gangrene and loss of circulation beyond the affected hand or foot. Smoking cessation leads to an 8-fold decrease in the risk for amputation. Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency. Buerger's disease is rarely immediately fatal, but rather a life shortening disease. Prognosis of Buerger's disease varies from person to person, depending on the patient's life-style and the severity of the damaged vessels.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of Buerger disease usually develop in the third to forth decade of life, and start with symptoms such as pallor and ischemia of the extremities.[1][2]
- If left untreated, approximately 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease.
Complications
- Common complications of Buerger disease include:[1][2]
- Amputation
- Gangrene
- Loss of circulation beyond the affected hand or foot
Prognosis
- Smoking cessation leads to an 8-fold decrease in the risk for amputation.[1][2]
- Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency.
- Buerger's disease is rarely immediately fatal, but rather a life shortening disease.
- Prognosis of Buerger's disease varies from person to person, depending on:
- The patient's life-style
- The severity of the damaged vessels
References
- ↑ 1.0 1.1 1.2 Ohta T, Ishioashi H, Hosaka M, Sugimoto I (January 2004). "Clinical and social consequences of Buerger disease". J. Vasc. Surg. 39 (1): 176–80. doi:10.1016/j.jvs.2003.08.006. PMID 14718836.
- ↑ 2.0 2.1 2.2 Cooper LT, Tse TS, Mikhail MA, McBane RD, Stanson AW, Ballman KV (December 2004). "Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease)". J. Am. Coll. Cardiol. 44 (12): 2410–1. doi:10.1016/j.jacc.2004.09.029. PMID 15607407.