Buergers disease: Difference between revisions

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'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information, click [[Buerger's disease (patient information)|here]]'''


{{Infobox_Disease |
  Name          = Buerger's disease |
  Image          = Buerger's Disease.JPG|
  Caption        = Buerger's Disease of the Hand|
  DiseasesDB    = 1762 |
  ICD10          = {{ICD10|I|73|1|i|70}} |
  ICD9          = {{ICD9|443.1}} |
  ICDO          = |
  OMIM          = 211480 |
  MedlinePlus    = |
  MeshName      = Thromboangiitis+Obliterans |
  MeshNumber    = C14.907.137.870 |
}}
{{Buerger's disease}}
{{Buerger's disease}}
{{CMG}}
{{CMG}};{{AE}}{{HM}}


{{SK}} Thromboangiitis obliterans
{{SK}} Thromboangiitis obliterans; Winiwarter-Buerger disease; Buerger disease; Endarteritis obliterans


:''Not to be confused with [[Berger's disease]] (IgA nephropathy)''
'''Not to be confused with [[Berger's disease]] (IgA nephropathy)'''


==Overview==
==[[Buerger's disease overview|Overview]]==
==[[Buerger's disease historical perspective|Historical Perspective]]==


==Features==
==[[Buerger's disease pathophysiology|Pathophysiology]]==
There is a recurrent acute and chronic [[inflammation]] and [[thrombosis]] of [[artery|arteries]] and [[vein]]s of the hands and feet. The main symptom is [[Pain and nociception|pain]] in the affected areas. [[Ulceration]]s and [[gangrene]] in the extremities are common [[Complication (medicine)|complication]]s, often resulting in the need for [[amputation]] of the involved extremity.
==[[Buerger's disease causes|Causes]]==
==[[Buerger's disease differential diagnosis|Differentiating Buerger's Disease from other Diseases]]==


==[[Buerger's disease epidemiology and demographics|Epidemiology and Demographics]]==
==[[Buerger's disease risk factors|Risk Factors]]==
==[[Buerger's disease natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==Diagnosis==
==Diagnosis==
A concrete diagnosis of thromboangiitis obliterans is often difficult as it relies heavily on exclusion of the conditions. The commonly followed diagnostic criteria are below although the criteria tend to differ slightly from author to author. Olin (2000) proposes the following criteria:<ref>Olin JW. ''Thromboangiitis obliterans (Buerger's disease).'' N Engl J Med 2000;343:864-9. PMID 10995867.</ref>
[[Buerger's disease criteria|Diagnostic Criteria]] | [[Buerger's disease history and symptoms|History and Symptoms]] | [[Buerger's disease physical examination|Physical Examination]] | [[Buerger's disease laboratory findings|Laboratory Findings]] | [[Buerger's disease echocardiography or ultrasound|Ultrasound ]] | [[Buerger's disease other imaging findings|Other Imaging Findings]] | [[Buerger's disease other diagnostic studies|Other Diagnostic Studies]]
# Age younger than 45 years
# Current (or recent) history of tobacco use
# Presence of distal extremity ischemia (indicated by claudication, pain at rest, ischemic ulcers or gangrene) documented by noninvasive vascular testing such as ultrasound
# Exclusion of autoimmune diseases, hypercoagulable states, and diabetes mellitus by laboratory tests.
# Exclusion of a proximal source of emboli by echocardiography and arteriography
# Consistent arteriographic findings in the clinically involved and noninvolved limbs.
 
==Diagnostic Findings==
 
<div align="left">
<gallery heights="175" widths="175">
Image:Upper burgers1.jpg|Thromboangiitis Obliterans (Buerger's disease): Arterial vascular disease associated with smoking. Note the blackened tips of middle and pinky fingers. <br> (Image courtesy of Charlie Goldberg, M.D.)
</gallery>
</div>


==Treatment==
==Treatment==
Symptoms are treated as there is no treatment for the disease. Cessation of tobacco use may slow any further progression of the disease.  [[Vascular surgery]] can sometimes be helpful in treating limbs with poor perfusion secondary to this disease.  Use of vascular growth factor and stem cell injections have been showing promise in clinical studies.
[[Buerger's disease medical therapy|Medical Therapy]] | [[Buerger's disease surgery|Surgery]] | [[Buerger's disease primary prevention|Primary Prevention]] | [[Buerger's disease cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Buerger's disease future or investigational therapies|Future or Investigational Therapies]]
 
==References==
 
{{Reflist|2}}
 
==External Links==
 
[http://www.microsurgeon.org/buergers_disease.htm Buerger's Disease]]


==Case Studies==
[[Buerger's disease case study one|Case #1]]
{{Circulatory system pathology}}
{{Circulatory system pathology}}


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[[tr:Buerger hastalığı]]
[[zh:血栓闭塞性脉管炎]]
[[zh:血栓闭塞性脉管炎]]
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[[Category:Cardiovascular diseases]]
[[Category:Cardiovascular diseases]]
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[[Category:Cardiology]]
[[Category:Rheumatology]]
[[Category:Rheumatology]]
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Latest revision as of 16:05, 12 April 2018

For patient information, click here

Buerger's disease Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Buerger's Disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

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History and Symptoms

Physical Examination

Laboratory Findings

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Synonyms and keywords: Thromboangiitis obliterans; Winiwarter-Buerger disease; Buerger disease; Endarteritis obliterans

Not to be confused with Berger's disease (IgA nephropathy)

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Buerger's Disease from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria | History and Symptoms | Physical Examination | Laboratory Findings | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1


de:Endangiitis obliterans he:מחלת בירגר nl:Ziekte van Buerger sv:Morbus Buerger


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