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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''DNA replication licensing factor MCM5''' is a [[protein]] that in humans is encoded by the ''MCM5'' [[gene]].<ref name="pmid8751386">{{cite journal | vauthors = Paul R, Hu B, Musahl C, Hameister H, Knippers R | title = Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5 | journal = Cytogenet Cell Genet | volume = 73 | issue = 4 | pages = 317–21 | date = Sep 1996 | pmid = 8751386 | pmc =  | doi = 10.1159/000134366 }}</ref><ref name="pmid10591208">{{cite journal | vauthors = Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP | title = The DNA sequence of human chromosome 22 | journal = Nature | volume = 402 | issue = 6761 | pages = 489–95 | date = Dec 1999 | pmid = 10591208 | pmc = | doi = 10.1038/990031 }}</ref><ref name="entrez">{{Cite web| title = Entrez Gene: MCM5 MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4174| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
| HGNCid = 6948
| Symbol = MCM5
| AltSymbols =; CDC46; MGC5315; P1-CDC46
| OMIM = 602696
| ECnumber = 
| Homologene = 4904
| MGIid = 103197
| GeneAtlas_image1 = PBB_GE_MCM5_216237_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_MCM5_201755_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0008094 |text = DNA-dependent ATPase activity}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0000074 |text = regulation of progression through cell cycle}} {{GNF_GO|id=GO:0006260 |text = DNA replication}} {{GNF_GO|id=GO:0006270 |text = DNA replication initiation}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 4174
    | Hs_Ensembl = ENSG00000100297
    | Hs_RefseqProtein = NP_006730
    | Hs_RefseqmRNA = NM_006739
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 22
    | Hs_GenLoc_start = 34126128
    | Hs_GenLoc_end = 34150494
    | Hs_Uniprot = P33992
    | Mm_EntrezGene = 17218
    | Mm_Ensembl = ENSMUSG00000005410
    | Mm_RefseqmRNA = NM_008566
    | Mm_RefseqProtein = NP_032592
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 8
    | Mm_GenLoc_start = 78005641
    | Mm_GenLoc_end = 78024177
    | Mm_Uniprot = Q52KC3
  }}
}}
'''MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)''', also known as '''MCM5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MCM5 MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4174| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.<ref name="entrez"/>
{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.<ref name="entrez">{{cite web | title = Entrez Gene: MCM5 MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4174| accessdate = }}</ref>
}}


==References==
== See also ==
{{reflist|2}}
*[[Mini Chromosome Maintenance]]
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal  | author=Burkhart R, Schulte D, Hu D, ''et al.'' |title=Interactions of human nuclear proteins P1Mcm3 and P1Cdc46. |journal=Eur. J. Biochem. |volume=228 |issue= 2 |pages= 431-8 |year= 1995 |pmid= 7705359 |doi=  }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | author=Hu B, Burkhart R, Schulte D, ''et al.'' |title=The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins. |journal=Nucleic Acids Res. |volume=21 |issue= 23 |pages= 5289-93 |year= 1994 |pmid= 8265339 |doi=  }}
*{{cite journal  | author=Paul R, Hu B, Musahl C, ''et al.'' |title=Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5. |journal=Cytogenet. Cell Genet. |volume=73 |issue= 4 |pages= 317-21 |year= 1996 |pmid= 8751386 |doi=  }}
*{{cite journal  | author=Ishimi Y, Ichinose S, Omori A, ''et al.'' |title=Binding of human minichromosome maintenance proteins with histone H3. |journal=J. Biol. Chem. |volume=271 |issue= 39 |pages= 24115-22 |year= 1996 |pmid= 8798650 |doi=  }}
*{{cite journal  | author=Fujita M, Kiyono T, Hayashi Y, Ishibashi M |title=In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP. |journal=J. Biol. Chem. |volume=272 |issue= 16 |pages= 10928-35 |year= 1997 |pmid= 9099751 |doi=  }}
*{{cite journal  | author=Tsuruga H, Yabuta N, Hashizume K, ''et al.'' |title=Expression, nuclear localization and interactions of human MCM/P1 proteins. |journal=Biochem. Biophys. Res. Commun. |volume=236 |issue= 1 |pages= 118-25 |year= 1997 |pmid= 9223437 |doi= 10.1006/bbrc.1997.6865 }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | author=Zhang JJ, Zhao Y, Chait BT, ''et al.'' |title=Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation. |journal=EMBO J. |volume=17 |issue= 23 |pages= 6963-71 |year= 1999 |pmid= 9843502 |doi= 10.1093/emboj/17.23.6963 }}
*{{cite journal  | author=Ohtani K, Iwanaga R, Nakamura M, ''et al.'' |title=Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F. |journal=Oncogene |volume=18 |issue= 14 |pages= 2299-309 |year= 1999 |pmid= 10327050 |doi= 10.1038/sj.onc.1202544 }}
*{{cite journal  | author=Dunham I, Shimizu N, Roe BA, ''et al.'' |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489-95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 }}
*{{cite journal  | author=DaFonseca CJ, Shu F, Zhang JJ |title=Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 6 |pages= 3034-9 |year= 2001 |pmid= 11248027 |doi= 10.1073/pnas.061487598 }}
*{{cite journal  | author=Going JJ, Keith WN, Neilson L, ''et al.'' |title=Aberrant expression of minichromosome maintenance proteins 2 and 5, and Ki-67 in dysplastic squamous oesophageal epithelium and Barrett's mucosa. |journal=Gut |volume=50 |issue= 3 |pages= 373-7 |year= 2002 |pmid= 11839717 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Kneissl M, Pütter V, Szalay AA, Grummt F |title=Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. |journal=J. Mol. Biol. |volume=327 |issue= 1 |pages= 111-28 |year= 2003 |pmid= 12614612 |doi=  }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Bouwmeester T, Bauch A, Ruffner H, ''et al.'' |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97-105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
*{{cite journal  | author=Ramachandran N, Hainsworth E, Bhullar B, ''et al.'' |title=Self-assembling protein microarrays. |journal=Science |volume=305 |issue= 5680 |pages= 86-90 |year= 2004 |pmid= 15232106 |doi= 10.1126/science.1097639 }}
*{{cite journal  | author=Yu Z, Feng D, Liang C |title=Pairwise interactions of the six human MCM protein subunits. |journal=J. Mol. Biol. |volume=340 |issue= 5 |pages= 1197-206 |year= 2004 |pmid= 15236977 |doi= 10.1016/j.jmb.2004.05.024 }}
*{{cite journal  | author=Jin J, Smith FD, Stark C, ''et al.'' |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436-50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 }}
}}
{{refend}}


{{gene-22-stub}}
== Interactions ==
{{WikiDoc Sources}}
 
MCM5 has been shown to [[Protein-protein interaction|interact]] with:
* [[Cell division cycle 7-related protein kinase]],<ref name = pmid12614612/>
* [[MCM2]],<ref name = pmid12614612/><ref name = pmid11248027/>
* [[MCM3]],<ref name = pmid12614612/><ref name = pmid11248027/>
* [[MCM7]],<ref name = pmid12614612/><ref name = pmid11248027>{{cite journal | vauthors = DaFonseca CJ, Shu F, Zhang JJ | title = Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 98 | issue = 6 | pages = 3034–9 | date = Mar 2001 | pmid = 11248027 | pmc = 30602 | doi = 10.1073/pnas.061487598 }}</ref><ref name = pmid9099751>{{cite journal | vauthors = Fujita M, Kiyono T, Hayashi Y, Ishibashi M | title = In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP | journal = J. Biol. Chem. | volume = 272 | issue = 16 | pages = 10928–35 | date = Apr 1997 | pmid = 9099751 | doi =  10.1074/jbc.272.16.10928}}</ref>
* [[ORC2L]],<ref name = pmid12614612>{{cite journal | vauthors = Kneissl M, Pütter V, Szalay AA, Grummt F | title = Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells | journal = J. Mol. Biol. | volume = 327 | issue = 1 | pages = 111–28 | date = Mar 2003 | pmid = 12614612 | doi =  10.1016/s0022-2836(03)00079-2}}</ref>
* [[ORC6L]],<ref name = pmid12614612/> and
* [[STAT1]].<ref name = pmid11248027/><ref name = pmid9843502>{{cite journal | vauthors = Zhang JJ, Zhao Y, Chait BT, Lathem WW, Ritzi M, Knippers R, Darnell JE | title = Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation | journal = EMBO J. | volume = 17 | issue = 23 | pages = 6963–71 | date = Dec 1998 | pmid = 9843502 | pmc = 1171044 | doi = 10.1093/emboj/17.23.6963 }}</ref>
 
== References ==
{{Reflist}}
 
== Further reading ==
{{Refbegin| 2}}
* {{cite journal | vauthors = Burkhart R, Schulte D, Hu D, Musahl C, Göhring F, Knippers R | title = Interactions of human nuclear proteins P1Mcm3 and P1Cdc46. | journal = Eur. J. Biochem. | volume = 228 | issue = 2 | pages = 431–8 | year = 1995 | pmid = 7705359 | doi = 10.1111/j.1432-1033.1995.tb20281.x }}
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
* {{cite journal | vauthors = Hu B, Burkhart R, Schulte D, Musahl C, Knippers R | title = The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins | journal = Nucleic Acids Res. | volume = 21 | issue = 23 | pages = 5289–93 | year = 1994 | pmid = 8265339 | pmc = 310560 | doi = 10.1093/nar/21.23.5289-a }}
* {{cite journal | vauthors = Ishimi Y, Ichinose S, Omori A, Sato K, Kimura H | title = Binding of human minichromosome maintenance proteins with histone H3 | journal = J. Biol. Chem. | volume = 271 | issue = 39 | pages = 24115–22 | year = 1996 | pmid = 8798650 | doi = 10.1074/jbc.271.39.24115 }}
* {{cite journal | vauthors = Fujita M, Kiyono T, Hayashi Y, Ishibashi M | title = In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP | journal = J. Biol. Chem. | volume = 272 | issue = 16 | pages = 10928–35 | year = 1997 | pmid = 9099751 | doi = 10.1074/jbc.272.16.10928 }}
* {{cite journal | vauthors = Tsuruga H, Yabuta N, Hashizume K, Ikeda M, Endo Y, Nojima H | title = Expression, nuclear localization and interactions of human MCM/P1 proteins | journal = Biochem. Biophys. Res. Commun. | volume = 236 | issue = 1 | pages = 118–25 | year = 1997 | pmid = 9223437 | doi = 10.1006/bbrc.1997.6865 }}
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
* {{cite journal | vauthors = Zhang JJ, Zhao Y, Chait BT, Lathem WW, Ritzi M, Knippers R, Darnell JE | title = Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation | journal = EMBO J. | volume = 17 | issue = 23 | pages = 6963–71 | year = 1999 | pmid = 9843502 | pmc = 1171044 | doi = 10.1093/emboj/17.23.6963 }}
* {{cite journal | vauthors = Ohtani K, Iwanaga R, Nakamura M, Ikeda M, Yabuta N, Tsuruga H, Nojima H | title = Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F | journal = Oncogene | volume = 18 | issue = 14 | pages = 2299–309 | year = 1999 | pmid = 10327050 | doi = 10.1038/sj.onc.1202544 }}
* {{cite journal | vauthors = DaFonseca CJ, Shu F, Zhang JJ | title = Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 98 | issue = 6 | pages = 3034–9 | year = 2001 | pmid = 11248027 | pmc = 30602 | doi = 10.1073/pnas.061487598 }}
* {{cite journal | vauthors = Going JJ, Keith WN, Neilson L, Stoeber K, Stuart RC, Williams GH | title = Aberrant expression of minichromosome maintenance proteins 2 and 5, and Ki-67 in dysplastic squamous oesophageal epithelium and Barrett's mucosa | journal = Gut | volume = 50 | issue = 3 | pages = 373–7 | year = 2002 | pmid = 11839717 | pmc = 1773132 | doi = 10.1136/gut.50.3.373 }}
* {{cite journal | vauthors = Kneissl M, Pütter V, Szalay AA, Grummt F | title = Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells | journal = J. Mol. Biol. | volume = 327 | issue = 1 | pages = 111–28 | year = 2003 | pmid = 12614612 | doi = 10.1016/S0022-2836(03)00079-2 }}
* {{cite journal | vauthors = Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G | title = A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway | journal = Nat. Cell Biol. | volume = 6 | issue = 2 | pages = 97–105 | year = 2004 | pmid = 14743216 | doi = 10.1038/ncb1086 }}
* {{cite journal | vauthors = Ramachandran N, Hainsworth E, Bhullar B, Eisenstein S, Rosen B, Lau AY, Walter JC, LaBaer J | title = Self-assembling protein microarrays | journal = Science | volume = 305 | issue = 5680 | pages = 86–90 | year = 2004 | pmid = 15232106 | doi = 10.1126/science.1097639 }}
* {{cite journal | vauthors = Yu Z, Feng D, Liang C | title = Pairwise interactions of the six human MCM protein subunits | journal = J. Mol. Biol. | volume = 340 | issue = 5 | pages = 1197–206 | year = 2004 | pmid = 15236977 | doi = 10.1016/j.jmb.2004.05.024 }}
* {{cite journal | vauthors = Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T | title = Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization | journal = Curr. Biol. | volume = 14 | issue = 16 | pages = 1436–50 | year = 2004 | pmid = 15324660 | doi = 10.1016/j.cub.2004.07.051 }}
{{Refend}}
 
 
{{Gene-22-stub}}

Latest revision as of 06:16, 4 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

DNA replication licensing factor MCM5 is a protein that in humans is encoded by the MCM5 gene.[1][2][3]

Function

The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.[3]

See also

Interactions

MCM5 has been shown to interact with:

References

  1. ↑ Paul R, Hu B, Musahl C, Hameister H, Knippers R (Sep 1996). "Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5". Cytogenet Cell Genet. 73 (4): 317–21. doi:10.1159/000134366. PMID 8751386.
  2. ↑ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
  3. ↑ 3.0 3.1 "Entrez Gene: MCM5 MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)".
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Kneissl M, Pütter V, Szalay AA, Grummt F (Mar 2003). "Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells". J. Mol. Biol. 327 (1): 111–28. doi:10.1016/s0022-2836(03)00079-2. PMID 12614612.
  5. ↑ 5.0 5.1 5.2 5.3 DaFonseca CJ, Shu F, Zhang JJ (Mar 2001). "Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma". Proc. Natl. Acad. Sci. U.S.A. 98 (6): 3034–9. doi:10.1073/pnas.061487598. PMC 30602. PMID 11248027.
  6. ↑ Fujita M, Kiyono T, Hayashi Y, Ishibashi M (Apr 1997). "In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP". J. Biol. Chem. 272 (16): 10928–35. doi:10.1074/jbc.272.16.10928. PMID 9099751.
  7. ↑ Zhang JJ, Zhao Y, Chait BT, Lathem WW, Ritzi M, Knippers R, Darnell JE (Dec 1998). "Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation". EMBO J. 17 (23): 6963–71. doi:10.1093/emboj/17.23.6963. PMC 1171044. PMID 9843502.

Further reading


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