OR10A5: Difference between revisions

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Latest revision as of 00:27, 7 September 2017

Olfactory receptor 10A5 is a protein that in humans is encoded by the OR10A5 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

References

↑ ^1.0 ^1.1 "Entrez Gene: OR10A5 olfactory receptor, family 10, subfamily A, member 5".

Buettner JA, Glusman G, Ben-Arie N, et al. (1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077.
Lane RP, Cutforth T, Young J, et al. (2001). "Genomic analysis of orthologous mouse and human olfactory receptor loci". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7390–5. doi:10.1073/pnas.131215398. PMC 34679. PMID 11416212.
Gaudin JC, Breuils L, Haertlé T (2002). "New GPCRs from a human lingual cDNA library". Chem. Senses. 26 (9): 1157–66. doi:10.1093/chemse/26.9.1157. PMID 11705801.
Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

OR10A5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[entrez-1] 1.0 ^1.1 "Entrez Gene: OR10A5 olfactory receptor, family 10, subfamily A, member 5".

[1]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
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+'''Olfactory receptor 10A5''' is a [[protein]] that in humans is encoded by the ''OR10A5'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR10A5 olfactory receptor, family 10, subfamily A, member 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=144124| accessdate = }}</ref>
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- | image =
- | image_source =
- | PDB =
- | Name = Olfactory receptor, family 10, subfamily A, member 5
- | HGNCid = 15131
- | Symbol = OR10A5
- | AltSymbols =; JCG6; OR10A1; OR11-403
- | OMIM = 608493
- | ECnumber =
- | Homologene = 17470
- | MGIid = 3030547
- | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
- | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
- | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 144124
-    | Hs_Ensembl = ENSG00000166363
-    | Hs_RefseqProtein = NP_835462
-    | Hs_RefseqmRNA = NM_178168
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 11
-    | Hs_GenLoc_start = 6823459
-    | Hs_GenLoc_end = 6824512
-    | Hs_Uniprot = Q9H207
-    | Mm_EntrezGene = 259036
-    | Mm_Ensembl = ENSMUSG00000073898
-    | Mm_RefseqmRNA = NM_147034
-    | Mm_RefseqProtein = NP_667245
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 7
-    | Mm_GenLoc_start = 106829785
-    | Mm_GenLoc_end = 106830759
-    | Mm_Uniprot =
-  }}
-}}
-'''Olfactory receptor, family 10, subfamily A, member 5''', also known as '''OR10A5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR10A5 olfactory receptor, family 10, subfamily A, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=144124| accessdate = }}</ref>
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 {{PBB_Summary
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-| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR10A5 olfactory receptor, family 10, subfamily A, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=144124| accessdate = }}</ref>
+| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR10A5 olfactory receptor, family 10, subfamily A, member 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=144124| accessdate = }}</ref>
 }}
@@ Line 57: / Line 12: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
@@ Line 63: / Line 18: @@
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Buettner JA, Glusman G, Ben-Arie N, ''et al.'' |title=Organization and evolution of olfactory receptor genes on human chromosome 11. |journal=Genomics |volume=53 |issue= 1 |pages= 56-68 |year= 1998 |pmid= 9787077 |doi= 10.1006/geno.1998.5422 }}
+*{{cite journal   |vauthors=Buettner JA, Glusman G, Ben-Arie N, etal |title=Organization and evolution of olfactory receptor genes on human chromosome 11. |journal=Genomics |volume=53 |issue= 1 |pages= 56–68 |year= 1998 |pmid= 9787077 |doi= 10.1006/geno.1998.5422 }}
-*{{cite journal  | author=Lane RP, Cutforth T, Young J, ''et al.'' |title=Genomic analysis of orthologous mouse and human olfactory receptor loci. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 13 |pages= 7390-5 |year= 2001 |pmid= 11416212 |doi= 10.1073/pnas.131215398 }}
+*{{cite journal   |vauthors=Lane RP, Cutforth T, Young J, etal |title=Genomic analysis of orthologous mouse and human olfactory receptor loci. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 13 |pages= 7390–5 |year= 2001 |pmid= 11416212 |doi= 10.1073/pnas.131215398  | pmc=34679 }}
-*{{cite journal  | author=Gaudin JC, Breuils L, Haertlé T |title=New GPCRs from a human lingual cDNA library. |journal=Chem. Senses |volume=26 |issue= 9 |pages= 1157-66 |year= 2002 |pmid= 11705801 |doi=  }}
+*{{cite journal  | vauthors=Gaudin JC, Breuils L, Haertlé T |title=New GPCRs from a human lingual cDNA library. |journal=Chem. Senses |volume=26 |issue= 9 |pages= 1157–66 |year= 2002 |pmid= 11705801 |doi=10.1093/chemse/26.9.1157  }}
-*{{cite journal  | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi=  }}
+*{{cite journal   |vauthors=Fuchs T, Malecova B, Linhart C, etal |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi=  }}
+*{{cite journal  | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993  }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
 }}
 {{refend}}
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 {{NLM content}}
-{{membrane-protein-stub}}
 {{Olfactory receptors}}
-[[Category:G protein coupled receptors]]
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+[[Category:Olfactory receptors]]
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OR10A5: Difference between revisions

Latest revision as of 00:27, 7 September 2017

Contents

See also

References

Further reading

External links

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