SCAMP1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Secretory carrier-associated membrane protein 1''' is a [[protein]] that in humans is encoded by the ''SCAMP1'' [[gene]].<ref name="pmid9378760">{{cite journal | vauthors = Singleton DR, Wu TT, Castle JD | title = Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions | journal = Journal of Cell Science | volume = 110 ( Pt 17) | issue =  | pages = 2099–107 | date = September 1997 | pmid = 9378760 | pmc =  | doi = | series = 110 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SCAMP1 secretory carrier membrane protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9522| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Secretory carrier membrane protein 1
| HGNCid = 10563
| Symbol = SCAMP1
| AltSymbols =; SCAMP; SCAMP37
| OMIM = 606911
| ECnumber = 
| Homologene = 37975
| MGIid = 1349480
| GeneAtlas_image1 = PBB_GE_SCAMP1_212416_at_tn.png
| GeneAtlas_image2 = PBB_GE_SCAMP1_206667_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_SCAMP1_206668_s_at_tn.png
| Function =  
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} {{GNF_GO|id=GO:0030672 |text = synaptic vesicle membrane}} {{GNF_GO|id=GO:0042589 |text = zymogen granule membrane}}
| Process = {{GNF_GO|id=GO:0006887 |text = exocytosis}} {{GNF_GO|id=GO:0006892 |text = post-Golgi vesicle-mediated transport}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9522
    | Hs_Ensembl = ENSG00000085365
    | Hs_RefseqProtein = NP_438173
    | Hs_RefseqmRNA = NM_052822
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 5
    | Hs_GenLoc_start = 77692110
    | Hs_GenLoc_end = 77810634
    | Hs_Uniprot = O15126
    | Mm_EntrezGene = 107767
    | Mm_Ensembl = ENSMUSG00000021687
    | Mm_RefseqmRNA = NM_029153
    | Mm_RefseqProtein = NP_083429
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 13
    | Mm_GenLoc_start = 95302187
    | Mm_GenLoc_end = 95385980
    | Mm_Uniprot = Q3TD71
  }}
}}
'''Secretory carrier membrane protein 1''', also known as '''SCAMP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SCAMP1 secretory carrier membrane protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9522| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways.<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways.<ref name="entrez">{{cite web | title = Entrez Gene: SCAMP1 secretory carrier membrane protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9522| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
SCAMP1 has been shown to [[Protein-protein interaction|interact]] with [[ITSN1]]<ref name=pmid10777571>{{cite journal | vauthors = Fernández-Chacón R, Achiriloaie M, Janz R, Albanesi JP, Südhof TC | title = SCAMP1 function in endocytosis | journal = The Journal of Biological Chemistry | volume = 275 | issue = 17 | pages = 12752–6 | date = April 2000 | pmid = 10777571 | doi = 10.1074/jbc.275.17.12752 }}</ref> and [[AP1GBP1]].<ref name=pmid10777571/>
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1-2 | pages = 171–4 | date = January 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
| citations =
* {{cite journal | vauthors = Brand SH, Castle JD | title = SCAMP 37, a new marker within the general cell surface recycling system | journal = The EMBO Journal | volume = 12 | issue = 10 | pages = 3753–61 | date = October 1993 | pmid = 8404846 | pmc = 413657 | doi =  }}
*{{cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = April 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
*{{cite journal | author=Brand SH, Castle JD |title=SCAMP 37, a new marker within the general cell surface recycling system. |journal=EMBO J. |volume=12 |issue= 10 |pages= 3753-61 |year= 1993 |pmid= 8404846 |doi=  }}
* {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = April 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
* {{cite journal | vauthors = Wu TT, Castle JD | title = Evidence for colocalization and interaction between 37 and 39 kDa isoforms of secretory carrier membrane proteins (SCAMPs) | journal = Journal of Cell Science | volume = 110 ( Pt 13) | issue =  | pages = 1533–41 | date = July 1997 | pmid = 9224770 | doi =  | series = 110 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi= }}
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1-2 | pages = 149–56 | date = October 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Wu TT, Castle JD |title=Evidence for colocalization and interaction between 37 and 39 kDa isoforms of secretory carrier membrane proteins (SCAMPs). |journal=J. Cell. Sci. |volume=110 ( Pt 13) |issue=  |pages= 1533-41 |year= 1997 |pmid= 9224770 |doi=  }}
* {{cite journal | vauthors = Mao M, Fu G, Wu JS, Zhang QH, Zhou J, Kan LX, Huang QH, He KL, Gu BW, Han ZG, Shen Y, Gu J, Yu YP, Xu SH, Wang YX, Chen SJ, Chen Z | title = Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 14 | pages = 8175–80 | date = July 1998 | pmid = 9653160 | pmc = 20949 | doi = 10.1073/pnas.95.14.8175 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
* {{cite journal | vauthors = Wu TT, Castle JD | title = Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor | journal = Molecular Biology of the Cell | volume = 9 | issue = 7 | pages = 1661–74 | date = July 1998 | pmid = 9658162 | pmc = 25404 | doi = 10.1091/mbc.9.7.1661 }}
*{{cite journal  | author=Singleton DR, Wu TT, Castle JD |title=Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions. |journal=J. Cell. Sci. |volume=110 ( Pt 17) |issue=  |pages= 2099-107 |year= 1997 |pmid= 9378760 |doi=  }}
* {{cite journal | vauthors = Fernández-Chacón R, Achiriloaie M, Janz R, Albanesi JP, Südhof TC | title = SCAMP1 function in endocytosis | journal = The Journal of Biological Chemistry | volume = 275 | issue = 17 | pages = 12752–6 | date = April 2000 | pmid = 10777571 | doi = 10.1074/jbc.275.17.12752 }}
*{{cite journal | author=Mao M, Fu G, Wu JS, ''et al.'' |title=Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 14 |pages= 8175-80 |year= 1998 |pmid= 9653160 |doi= }}
* {{cite journal | vauthors = Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z | title = Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells | journal = Genome Research | volume = 10 | issue = 10 | pages = 1546–60 | date = October 2000 | pmid = 11042152 | pmc = 310934 | doi = 10.1101/gr.140200 }}
*{{cite journal | author=Wu TT, Castle JD |title=Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor. |journal=Mol. Biol. Cell |volume=9 |issue= 7 |pages= 1661-74 |year= 1999 |pmid= 9658162 |doi= }}
* {{cite journal | vauthors = Bell AW, Ward MA, Blackstock WP, Freeman HN, Choudhary JS, Lewis AP, Chotai D, Fazel A, Gushue JN, Paiement J, Palcy S, Chevet E, Lafrenière-Roula M, Solari R, Thomas DY, Rowley A, Bergeron JJ | title = Proteomics characterization of abundant Golgi membrane proteins | journal = The Journal of Biological Chemistry | volume = 276 | issue = 7 | pages = 5152–65 | date = February 2001 | pmid = 11042173 | doi = 10.1074/jbc.M006143200 }}
*{{cite journal | author=Fernández-Chacón R, Achiriloaie M, Janz R, ''et al.'' |title=SCAMP1 function in endocytosis. |journal=J. Biol. Chem. |volume=275 |issue= 17 |pages= 12752-6 |year= 2000 |pmid= 10777571 |doi= }}
* {{cite journal | vauthors = Fernández-Chacón R, Südhof TC | title = Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle-specific forms implicate SCAMPs in multiple membrane-trafficking functions | journal = The Journal of Neuroscience | volume = 20 | issue = 21 | pages = 7941–50 | date = November 2000 | pmid = 11050114 | doi =  }}
*{{cite journal | author=Zhang QH, Ye M, Wu XY, ''et al.'' |title=Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. |journal=Genome Res. |volume=10 |issue= 10 |pages= 1546-60 |year= 2001 |pmid= 11042152 |doi= }}
* {{cite journal | vauthors = Guo Z, Liu L, Cafiso D, Castle D | title = Perturbation of a very late step of regulated exocytosis by a secretory carrier membrane protein (SCAMP2)-derived peptide | journal = The Journal of Biological Chemistry | volume = 277 | issue = 38 | pages = 35357–63 | date = September 2002 | pmid = 12124380 | doi = 10.1074/jbc.M202259200 }}
*{{cite journal | author=Bell AW, Ward MA, Blackstock WP, ''et al.'' |title=Proteomics characterization of abundant Golgi membrane proteins. |journal=J. Biol. Chem. |volume=276 |issue= 7 |pages= 5152-65 |year= 2001 |pmid= 11042173 |doi= 10.1074/jbc.M006143200 }}
* {{cite journal | vauthors = Liu L, Guo Z, Tieu Q, Castle A, Castle D | title = Role of secretory carrier membrane protein SCAMP2 in granule exocytosis | journal = Molecular Biology of the Cell | volume = 13 | issue = 12 | pages = 4266–78 | date = December 2002 | pmid = 12475951 | pmc = 138632 | doi = 10.1091/mbc.E02-03-0136 }}
*{{cite journal | author=Fernández-Chacón R, Südhof TC |title=Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle-specific forms implicate SCAMPs in multiple membrane-trafficking functions. |journal=J. Neurosci. |volume=20 |issue= 21 |pages= 7941-50 |year= 2001 |pmid= 11050114 |doi=  }}
* {{cite journal | vauthors = Hillman RT, Green RE, Brenner SE | title = An unappreciated role for RNA surveillance | journal = Genome Biology | volume = 5 | issue = 2 | pages = R8 | year = 2005 | pmid = 14759258 | pmc = 395752 | doi = 10.1186/gb-2004-5-2-r8 }}
*{{cite journal | author=Guo Z, Liu L, Cafiso D, Castle D |title=Perturbation of a very late step of regulated exocytosis by a secretory carrier membrane protein (SCAMP2)-derived peptide. |journal=J. Biol. Chem. |volume=277 |issue= 38 |pages= 35357-63 |year= 2002 |pmid= 12124380 |doi= 10.1074/jbc.M202259200 }}
* {{cite journal | vauthors = Lin PJ, Williams WP, Luu Y, Molday RS, Orlowski J, Numata M | title = Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7 | journal = Journal of Cell Science | volume = 118 | issue = Pt 9 | pages = 1885–97 | date = May 2005 | pmid = 15840657 | doi = 10.1242/jcs.02315 }}
*{{cite journal | author=Liu L, Guo Z, Tieu Q, ''et al.'' |title=Role of secretory carrier membrane protein SCAMP2 in granule exocytosis. |journal=Mol. Biol. Cell |volume=13 |issue= 12 |pages= 4266-78 |year= 2003 |pmid= 12475951 |doi= 10.1091/mbc.E02-03-0136 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance. |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Lin PJ, Williams WP, Luu Y, ''et al.'' |title=Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7. |journal=J. Cell. Sci. |volume=118 |issue= Pt 9 |pages= 1885-97 |year= 2005 |pmid= 15840657 |doi= 10.1242/jcs.02315 }}
}}
{{refend}}
{{refend}}


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Latest revision as of 05:57, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Secretory carrier-associated membrane protein 1 is a protein that in humans is encoded by the SCAMP1 gene.[1][2]

Function

This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways.[2]

Interactions

SCAMP1 has been shown to interact with ITSN1[3] and AP1GBP1.[3]

References

  1. ↑ Singleton DR, Wu TT, Castle JD (September 1997). "Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions". Journal of Cell Science. 110. 110 ( Pt 17): 2099–107. PMID 9378760.
  2. ↑ 2.0 2.1 "Entrez Gene: SCAMP1 secretory carrier membrane protein 1".
  3. ↑ 3.0 3.1 Fernández-Chacón R, Achiriloaie M, Janz R, Albanesi JP, Südhof TC (April 2000). "SCAMP1 function in endocytosis". The Journal of Biological Chemistry. 275 (17): 12752–6. doi:10.1074/jbc.275.17.12752. PMID 10777571.

Further reading

Retrieved from "https://www.wikidoc.org/index.php?title=SCAMP1&oldid=1420304"