U wave alternans: Difference between revisions
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==Overview== | ==Overview== | ||
U wave alternans is defined as beat to beat variation in the amplitude or axis of the [[U wave]]. | |||
==Classification== | |||
U wave alternans is one of several types of repolarization alternans which also includes [[ST segment alternans]] and [[T wave alternans]]. | |||
==Pathophysiology== | ==Pathophysiology== | ||
The underlying molecular mechanism is thought to involve abnormalities in calcium handling. | |||
==Causes== | ==Causes== | ||
*[[Alcoholism]] | |||
*[[Hypocalcemia]] | |||
*[[Hypokalemia]]<ref>Mullican WS Jr, Fisch C: Post extrasystolic alternans of the U wave due to hypokalemia. Am Heart J 68:383, 1964.</ref> | |||
*[[Hypomagnesemia]] | |||
*[[Pericardial effusion]] | |||
==Epidemiology and Demographics== | |||
U wave alternans is very rare. | |||
==Natural History, Complications, Prognosis== | |||
U wave alternans has been associated with an increased susceptibility to [[ventricular arrhythmias]].<ref>Mullican WS Jr, Fisch C: Post extrasystolic alternans of the U wave due to hypokalemia. Am Heart J 68:383, | |||
1964.</ref><ref>Tali Bashour; Jorge C. Rios; Patrick A. Gorman. CHEST.1973;64(3):377-379. doi:10.1378/chest.64.3.377</ref> | |||
==Treatment== | |||
Repletion of magnesium and calcium reversed the electrocardiographic abnormality and reduced ventricular irritability. <ref>Tali Bashour; Jorge C. Rios; Patrick A. Gorman. CHEST.1973;64(3):377-379. doi:10.1378/chest.64.3.377</ref> | |||
==References== | ==References== | ||
Latest revision as of 23:27, 8 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Related chapter: electrical alternans
Overview
U wave alternans is defined as beat to beat variation in the amplitude or axis of the U wave.
Classification
U wave alternans is one of several types of repolarization alternans which also includes ST segment alternans and T wave alternans.
Pathophysiology
The underlying molecular mechanism is thought to involve abnormalities in calcium handling.
Causes
Epidemiology and Demographics
U wave alternans is very rare.
Natural History, Complications, Prognosis
U wave alternans has been associated with an increased susceptibility to ventricular arrhythmias.[2][3]
Treatment
Repletion of magnesium and calcium reversed the electrocardiographic abnormality and reduced ventricular irritability. [4]
References
- ↑ Mullican WS Jr, Fisch C: Post extrasystolic alternans of the U wave due to hypokalemia. Am Heart J 68:383, 1964.
- ↑ Mullican WS Jr, Fisch C: Post extrasystolic alternans of the U wave due to hypokalemia. Am Heart J 68:383, 1964.
- ↑ Tali Bashour; Jorge C. Rios; Patrick A. Gorman. CHEST.1973;64(3):377-379. doi:10.1378/chest.64.3.377
- ↑ Tali Bashour; Jorge C. Rios; Patrick A. Gorman. CHEST.1973;64(3):377-379. doi:10.1378/chest.64.3.377