Nasopharyngeal carcinoma classification: Difference between revisions

	Nasopharyngeal carcinoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Nasopharyngeal carcinoma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Interventions
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Nasopharyngeal carcinoma classification On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Nasopharyngeal carcinoma classification All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Nasopharyngeal carcinoma classification
CDC on Nasopharyngeal carcinoma classification
Nasopharyngeal carcinoma classification in the news
Blogs on Nasopharyngeal carcinoma classification
Directions to Hospitals Treating Nasopharyngeal carcinoma
Risk calculators and risk factors for Nasopharyngeal carcinoma classification

VisualWikitext

Latest revision as of 22:53, 29 July 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]Faizan Sheraz, M.D. [3]

Overview

World health organization classified nasopharyngeal carcinoma into 3 types : keratinizing, nonkeratinizing (differentiated, undifferentiated) and basaloid squamous cell carcinoma.

Classification

World Health Organization (WHO) classification (2005) for nasopharyngeal carcinoma (NPC):^[1]^[2]

Classification	Former name	EBV	Prevalence	Prognosis
Keratinizing	Type 1, squamous cell carcinoma	-ve	almost 1/4 of NPC cases	poor
Nonkeratinizing, differentiated	Type 2, transitional carcinoma	+ve	less than 1/6 of NPC cases	good
Nonkeratinizing, undifferentiated	Type 3, lymphoepithelial carcinoma	+ve	most common	good
Basaloid squamous cell carcinoma (BSCC)			least common	poor

References

↑ Barnes, Leon (2005). Pathology and genetics of head and neck tumours. Lyon: IARC Press. ISBN 978-92-832-2417-4.
↑ Thompson, Lester (2011). Diagnostic pathology. Salt Lake City, Utah: Amirsys. ISBN 1931884617.

Template:WikiDoc Sources

[1] Barnes, Leon (2005). Pathology and genetics of head and neck tumours. Lyon: IARC Press. ISBN 978-92-832-2417-4.

[2] Thompson, Lester (2011). Diagnostic pathology. Salt Lake City, Utah: Amirsys. ISBN 1931884617.

[1]

[2]

@@ Line 1: / Line 1: @@
-__NOTOC__
-Please help WikiDoc by adding more content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.
 {{Nasopharyngeal carcinoma}}
-{{CMG}}
+{{CMG}}{{AE}}{{Homa}}{{Faizan}}
 ==Overview==
+[[World Health Organization|World health organization]] classified nasopharyngeal carcinoma into 3 types : keratinizing, nonkeratinizing (differentiated, undifferentiated) and basaloid squamous cell carcinoma.
 ==Classification==
-Nasopharyngeal carcinoma is classified as a malignant [[neoplasia|neoplasm]], or [[cancer]], arising from the [[mucosa]]l [[epithelium]] of the [[nasopharynx]], most often within the ''lateral nasopharyngeal recess'' or ''fossa of Rosenmüller''. There are three [[histopathology|microscopic]] subtypes of NPC: a well-differentiated ''[[keratin]]izing'' type, a moderately-differentiated ''nonkeratinizing'' type, and an ''undifferentiated'' type, which typically contains large numbers of non-cancerous [[lymphocytes]] (chronic inflammatory cells), thus giving rise to the name ''[[lymphoepithelioma]]''. The undifferentiated form is most common, and is most strongly associated with [[Epstein-Barr virus]] infection of the cancerous cells.<ref name="Weidner's">{{cite book |author=Richard Cote, Saul Suster, Lawrence Weiss, Noel Weidner (Editor) |title=Modern Surgical Pathology (2 Volume Set) |publisher=W B Saunders |location=London |year= |pages= |isbn=0-7216-7253-1 |oclc= |doi=}}</ref>
+[[World Health Organization]] ([[WHO]]) [[classification]] (2005) for nasopharyngeal carcinoma (NPC):<ref>{{cite book | last = Barnes | first = Leon | title = Pathology and genetics of head and neck tumours | publisher = IARC Press | location = Lyon | year = 2005 | isbn = 978-92-832-2417-4 }}</ref><ref>{{cite book | last = Thompson | first = Lester | title = Diagnostic pathology | publisher = Amirsys | location = Salt Lake City, Utah | year = 2011 | isbn = 1931884617 }}</ref>
-<gallery>
+{| class="wikitable"
-Image:Lymphoepithelioma met to LN 4.jpg|Undifferentiated nasopharyngeal carcinoma - low power
+! Classification
-Image:Lymphoepithelioma met to LN 1.jpg|Undifferentiated nasopharyngeal carcinoma - med. power
+! Former name
-Image:Lymphoepithelioma met to LN 2.jpg|Undifferentiated nasopharyngeal carcinoma - high power
+! EBV
-</gallery>
+! Prevalence
+! Prognosis
+|-
+| Keratinizing
+|Type 1, squamous cell carcinoma
+| -ve
+|almost 1/4 of NPC cases
+| poor
+|-
+| Nonkeratinizing, differentiated
+|Type 2, transitional carcinoma
+| +ve
+|less than 1/6 of NPC cases
+| good
+|-
+| Nonkeratinizing, undifferentiated
+|Type 3, lymphoepithelial carcinoma
+|<nowiki>+ve</nowiki>
+| most common
+|good
+|-
+| Basaloid squamous cell carcinoma (BSCC)
+|
+|
+| least common
+|poor
+|}
 ==References==
@@ Line 18: / Line 44: @@
 {{WikiDoc Sources}}
-[[Category:Disease]]
+[[Category:Up-To-Date]]
+[[Category:Medicine]]
-[[Category:Types of cancer]]
 [[Category:Oncology]]
+[[Category:Otolaryngology]]

Nasopharyngeal carcinoma classification: Difference between revisions

Latest revision as of 22:53, 29 July 2020

Overview

Classification

References

Navigation menu

Search